The role of mechanochemistry and supramolecular design in the development of pharmaceutical materials

Softening and Hardening of Macro- and Nano-Sized Organic Cocrystals in a Single-Crystal Transformation

(2011) Chandana Karunatilaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Cocrystal Strategy to Tune the Luminescent Properties of Stilbene-Type Organic Solid-State Materials

(2011) Dongpeng Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanosynthesis of the Metallodrug Bismuth Subsalicylate from Bi2O3 and Structure of Bismuth Salicylate without Auxiliary Organic Ligands

(2011) Vânia André et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanochemistry: opportunities for new and cleaner synthesis

(2011) Stuart L. James et al.   CHEMICAL SOCIETY REVIEWS

Ionic Co-crystals of Organic Molecules with Metal Halides: A New Prospect in the Solid Formulation of Active Pharmaceutical Ingredients

(2011) Dario Braga et al.   CRYSTAL GROWTH & DESIGN

Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals

(2011) N. Jagadeesh Babu et al.   CRYSTAL GROWTH & DESIGN

Highly soluble olanzapinium maleate crystalline salts

(2011) Ranjit Thakuria et al.   CRYSTENGCOMM

A rational approach to screen for hydrated forms of the pharmaceutical derivative magnesium naproxen using liquid-assisted grinding

(2011) Tomislav Friščić et al.   CRYSTENGCOMM

Crystal engineering: origins, early adventures and some current trends

(2011) John Meurig Thomas   CRYSTENGCOMM

Successful prediction of a model pharmaceutical in the fifth blind test of crystal structure prediction

(2011) Andrei V. Kazantsev et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploiting powder X-ray diffraction for direct structure determination in structural biology: The P2X4 receptor trafficking motif YEQGL

(2011) Kotaro Fujii et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Crystal Structure of D-Ribose-At Last!

(2010) Dubravka Šišak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supramolecular Catalysis in the Organic Solid State through Dry Grinding

(2010) Anatoliy N. Sokolov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pharmaceutical Nano-Cocrystals: Sonochemical Synthesis by Solvent Selection and Use of a Surfactant

(2010) John R. G. Sander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards an environmentally-friendly laboratory: dimensionality and reactivity in the mechanosynthesis of metal–organic compounds

(2010) Vjekoslav Štrukil et al.   CHEMICAL COMMUNICATIONS

Mechanochemistry of magnesium oxide revisited: facile derivatisation of pharmaceuticals using coordination and supramolecular chemistry

(2010) Ernest H. H. Chow et al.   CHEMICAL COMMUNICATIONS

From unexpected reactions to a new family of ionic co-crystals: the case of barbituric acid with alkali bromides and caesium iodide

(2010) Dario Braga et al.   CHEMICAL COMMUNICATIONS

Selective transformation pathways between crystalline forms of an organic material established from powder X-ray diffraction analysis

(2010) Kotaro Fujii et al.   CHEMICAL COMMUNICATIONS

The Richest Collection of Tautomeric Polymorphs: The Case of 2-Thiobarbituric Acid

(2010) Michele R. Chierotti et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Comparison of Cocrystal Structure Solutions from Powder and Single Crystal Techniques

(2010) Saul H. Lapidus et al.   CRYSTAL GROWTH & DESIGN

Cocrystal Eutectic Constants and Prediction of Solubility Behavior

(2010) David J. Good et al.   CRYSTAL GROWTH & DESIGN

A stepwise mechanism and the role of water in the liquid-assisted grinding synthesis of metal–organic materials

(2010) Fiona C. Strobridge et al.   CRYSTENGCOMM

Remarkable reversal of melting point alternation by co-crystallization

(2010) Dario Braga et al.   CRYSTENGCOMM

New solid forms of artemisinin obtained through cocrystallisation

(2010) Shyam Karki et al.   CRYSTENGCOMM

Thermally induced crystal-to-crystal transformations accompanied by changes in the magnetic properties of a CuII-p-hydroquinonate polymer

(2010) Ngoc Hien Phan et al.   CRYSTENGCOMM

Supramolecular metathesis: co-former exchange in co-crystals of pyrazine with (R,R)-, (S,S)-, (R,S)- and (S,S/R,R)-tartaric acid

(2010) Dario Braga et al.   CRYSTENGCOMM

Advantages of cocrystallization in the field of solid-state pharmaceutical chemistry: l-Proline and MnCl2

(2010) Anaëlle Tilborg et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Transmission Electron Microscopy of Pharmaceutical Materials

(2010) Mark D. Eddleston et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Powder Crystallography by Combined Crystal Structure Prediction and High-Resolution1H Solid-State NMR Spectroscopy

(2010) Elodie Salager et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computation and NMR crystallography of terbutaline sulfate

(2010) Robin K. Harris et al.   MAGNETIC RESONANCE IN CHEMISTRY

Improving Mechanical Properties of Crystalline Solids by Cocrystal Formation: New Compressible Forms of Paracetamol

(2009) Shyam Karki et al.   ADVANCED MATERIALS

Ion- and Liquid-Assisted Grinding: Improved Mechanochemical Synthesis of Metal-Organic Frameworks Reveals Salt Inclusion and Anion Templating

(2009) Tomislav Friščić et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hetero-Seeding and Solid Mixture to Obtain New Crystalline Forms

(2009) Dario Braga et al.   CHEMISTRY-A EUROPEAN JOURNAL

Molecular Crystal Prediction Approach by Molecular Similarity: Data Mining on Molecular Aggregation Predictors and Crystal Descriptors

(2009) Jose Fayos   CRYSTAL GROWTH & DESIGN

Understanding and Predicting the Effect of Cocrystal Components and pH on Cocrystal Solubility

(2009) Sarah J. Bethune et al.   CRYSTAL GROWTH & DESIGN

Cambridge Structural Database Analysis of Molecular Complementarity in Cocrystals

(2009) László Fábián   CRYSTAL GROWTH & DESIGN

Crystal Forms of the Antibiotic 4-Aminosalicylic Acid: Solvates and Molecular Salts with Dioxane, Morpholine, and Piperazine

(2009) Vânia André et al.   CRYSTAL GROWTH & DESIGN

Synthesis and Structural Characterization of Cocrystals and Pharmaceutical Cocrystals: Mechanochemistry vs Slow Evaporation from Solution

(2009) David R. Weyna et al.   CRYSTAL GROWTH & DESIGN

Recent Advances in Understanding the Mechanism of Cocrystal Formation via Grinding

(2009) Tomislav Friščić et al.   CRYSTAL GROWTH & DESIGN

Effects of Crystal Form on Solubility and Pharmacokinetics: A Crystal Engineering Case Study of Lamotrigine

(2009) Miranda L. Cheney et al.   CRYSTAL GROWTH & DESIGN

Drug-containing coordination and hydrogen bonding networks obtained mechanochemically

(2009) Dario Braga et al.   CRYSTENGCOMM

The mechanochemical synthesis of podand anion receptors

(2009) Adam N. Swinburne et al.   CRYSTENGCOMM

Cocrystal Controlled Solid-State Synthesis. A Green Chemistry Experiment for Undergraduate Organic Chemistry

(2009) Miranda L. Cheney et al.   JOURNAL OF CHEMICAL EDUCATION

Structural and thermal characterization of zolpidem hemitartrate hemihydrate (form E) and its decomposition products by laboratory x-ray powder diffraction

(2009) Ivan Halasz et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Using Cocrystals To Systematically Modulate Aqueous Solubility and Melting Behavior of an Anticancer Drug

(2009) Christer B. Aakeröy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Powder NMR crystallography of thymol

(2009) Elodie Salager et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Third structure determination by powder diffractometry round robin (SDPDRR-3)

(2009) A. Le Bail et al.   POWDER DIFFRACTION

Polymorphs and Polymorphic Cocrystals of Temozolomide

(2008) N. Jagadeesh Babu et al.   Chemistry-An Asian Journal

Mechanically Induced Phase Change in Barbituric Acid

(2008) Michele R. Chierotti et al.   CRYSTAL GROWTH & DESIGN

Effect of the Counterion on the Solubility of Isostructural Pharmaceutical Lamotrigine Salts

(2008) Judit Galcera et al.   CRYSTAL GROWTH & DESIGN

Simple and quantitative mechanochemical preparation of the first zinc and copper complexes of the neuroleptic drug gabapentin

(2008) Dario Braga et al.   CRYSTENGCOMM

Screening strategies based on solubility and solution composition generate pharmaceutically acceptable cocrystals of carbamazepine

(2008) Scott L. Childs et al.   CRYSTENGCOMM

A rapid thermal method for cocrystal screening

(2008) Enxian Lu et al.   CRYSTENGCOMM

The role of solvent in mechanochemical and sonochemical cocrystal formation: a solubility-based approach for predicting cocrystallisation outcome

(2008) Tomislav Friščić et al.   CRYSTENGCOMM

Control and interconversion of cocrystal stoichiometry in grinding: stepwise mechanism for the formation of a hydrogen-bonded cocrystal

(2008) Shyam Karki et al.   CRYSTENGCOMM

A Stepwise Mechanism for the Mechanochemical Synthesis of Halogen-Bonded Cocrystal Architectures

(2008) Dominik Cinčić et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanochemical assembly of hybrid organic–organometallic materials. Solid–solid reactions of 1,1′-di-pyridyl-ferrocene with organic acids

(2008) Dario Braga et al.   NEW JOURNAL OF CHEMISTRY