4.3 Article Proceedings Paper

Biomineralization of struvite crystals by Proteus mirabilis from artificial urine and their mesoscopic structure

Journal

CRYSTAL RESEARCH AND TECHNOLOGY
Volume 45, Issue 12, Pages 1283-1289

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/crat.201000344

Keywords

growth from solutions; biomineralization; bacteria induced growth; infectious urinary stones

Funding

  1. Polish Ministry of Science and Higher Education (MNiSzW) [N N202 033437]

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In order to investigate the mineralization of struvite we performed the experiment of struvite growth process from artificial urine. The crystallization process was induced by Proteus mirabilis, as these bacteria are mainly isolated from infectious stones. The crystallization process occurred at conditions mimicking the real urinary tract infection. Our results show that struvite exhibits polar properties. This feature of struvite crystals is potentially very important in the case of binding additives which may either enhance or inhibit crystallization process. It seems also that the differences in the polarity of opposite faces of c-axis play important role in directing the struvite mesoscopic arrangement. We also described recent developments concerning curcumin - pigment extracted from the roots of turmeric commonly known as a spice added to various food preparations. Curcumin exhibited the effect against Proteus mirabilis inhibiting the activity of urease and consequently decreasing the efficiency of struvite growth. Therefore, curcumin belongs to phytoterapheutic components, which may be the alternative with relation to the antibiotic therapy. The paper concludes with a future outlook and goals in this field of research. (C) 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

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