An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride

Vinyl acetate monomer (VAM) genotoxicity profile: Relevance for carcinogenicity

(2013) Richard J. Albertini   CRITICAL REVIEWS IN TOXICOLOGY

Polymorphisms in the coding region of X-ray repair complementing group 4 and aflatoxin B1-related hepatocellular carcinoma

(2013) Xi-Dai Long et al.   HEPATOLOGY

A New LC-MS/MS Method for the Quantification of Endogenous and Vinyl Chloride-Induced 7-(2-Oxoethyl)Guanine in Sprague–Dawley Rats

(2012) Esra Mutlu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

(2012) A. Mangerich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary modulation of the biotransformation and genotoxicity of aflatoxin B1

(2012) Kerstin Gross-Steinmeyer et al.   TOXICOLOGY

The rainbow trout liver cancer model: Response to environmental chemicals and studies on promotion and chemoprevention

(2011) David E. Williams   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Present and future directions of translational research on aflatoxin and hepatocellular carcinoma. A review

(2011) Gerald N. Wogan et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

DNA repair gene XRCC7 polymorphisms (rs#7003908 and rs#10109984) and hepatocellular carcinoma related to AFB1 exposure among Guangxi population, China

(2011) Xi-Dai Long et al.   HEPATOLOGY RESEARCH

Dietary supplementation with whey protein and ginseng extract counteracts oxidative stress and DNA damage in rats fed an aflatoxin-contaminated diet

(2011) Sekena H. Abdel-Aziem et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Aflatoxin B1-DNA Adduct Formation and Mutagenicity in Livers of Neonatal Male and Female B6C3F1 Mice

(2011) Leslie L. Woo et al.   TOXICOLOGICAL SCIENCES

Sulforaphane-Mediated Reduction of Aflatoxin B1-N7-Guanine in Rat Liver DNA: Impacts of Strain and Sex

(2011) Jeannette L. A. Fiala et al.   TOXICOLOGICAL SCIENCES

Development and Application of an LC-MS/MS Method for the Detection of the Vinyl Chloride-Induced DNA AdductN2,3-Ethenoguanine in Tissues of Adult and Weanling Rats Following Exposure to [13C2]-VC

(2010) Esra Mutlu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Monitoring of Endometrial K-ras Mutation in Tamoxifen-Treated Patients With Breast Cancer

(2010) Hiroshi Tsujioka et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial

(2010) D Serrano et al.   PHARMACOGENOMICS JOURNAL

Sulforaphane- and Phenethyl Isothiocyanate–Induced Inhibition of Aflatoxin B1–Mediated Genotoxicity in Human Hepatocytes: Role of GSTM1 Genotype and CYP3A4 Gene Expression

(2010) Kerstin Gross-Steinmeyer et al.   TOXICOLOGICAL SCIENCES

Endogenous versus Exogenous DNA Adducts: Their Role in Carcinogenesis, Epidemiology, and Risk Assessment

(2010) J. A. Swenberg et al.   TOXICOLOGICAL SCIENCES

Aflatoxin: A 50-Year Odyssey of Mechanistic and Translational Toxicology

(2010) T. W. Kensler et al.   TOXICOLOGICAL SCIENCES

Gene–environment interactions between DNA repair polymorphisms and exposure to the carcinogen vinyl chloride

(2009) Yongliang Li et al.   BIOMARKERS

Differences in Metabolite-Mediated Toxicity of Tamoxifen in Rodents versus Humans Elucidated with DNA/Microsome Electro-Optical Arrays and Nanoreactors

(2009) Linlin Zhao et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nonlinear Cancer Response at Ultralow Dose: A 40800-Animal ED001Tumor and Biomarker Study

(2009) George S. Bailey et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pharmacogenomics of Tamoxifen Therapy

(2009) H. Brauch et al.   CLINICAL CHEMISTRY

Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens

(2009) Alan R. Boobis et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Key Events Dose-Response Framework: A Cross-Disciplinary Mode-of-Action Based Approach to Examining Dose-Response and Thresholds

(2009) Elizabeth Julien* et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization

(2009) Annie M. Jarabek et al.   CRITICAL REVIEWS IN TOXICOLOGY

Creating context for the use of DNA adduct data in cancer risk assessment: II. Overview of methods of identification and quantitation of DNA damage

(2009) Matthew W. Himmelstein et al.   CRITICAL REVIEWS IN TOXICOLOGY

Tamoxifen-Induced Adduct Formation and Cell Stress in Human Endometrial Glands

(2009) H. Andersson et al.   DRUG METABOLISM AND DISPOSITION

Is tamoxifen a genotoxic carcinogen in women?

(2009) K. Brown   MUTAGENESIS

ECETOC workshop on the biological significance of DNA adducts: Summary of follow-up from an Expert Panel Meeting

(2009) Lynn H. Pottenger et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The formation and biological significance of N7-guanine adducts

(2009) Gunnar Boysen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Transgenic Expression of Aflatoxin Aldehyde Reductase (AKR7A1) Modulates Aflatoxin B1 Metabolism but not Hepatic Carcinogenesis in the Rat

(2009) Bill D. Roebuck et al.   TOXICOLOGICAL SCIENCES

Hemangiosarcoma in Rodents: Mode-of-Action Evaluation and Human Relevance

(2009) Samuel M. Cohen et al.   TOXICOLOGICAL SCIENCES

Subchronic mycotoxicoses in Wistar rats: Assessment of the in vivo and in vitro genotoxicity induced by fumonisins and aflatoxin B1, and oxidative stress biomarkers status

(2009) M.G. Theumer et al.   TOXICOLOGY

Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1

(2009) Zoran Ilic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Polymorphism of XRCC3 Codon 241 and AFB1-Related Hepatocellular Carcinoma in Guangxi Population, China

(2008) Xi Dai Long et al.   ANNALS OF EPIDEMIOLOGY

Human Aflatoxin Albumin Adducts Quantitatively Compared by ELISA, HPLC with Fluorescence Detection, and HPLC with Isotope Dilution Mass Spectrometry

(2008) L. F. McCoy et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Long-term Stability of Human Aflatoxin B1 Albumin Adducts Assessed by Isotope Dilution Mass Spectrometry and High-Performance Liquid Chromatography-Fluorescence

(2008) P. F. Scholl et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hepatitis B virus infection contributes to oxidative stress in a population exposed to aflatoxin B1 and high-risk for hepatocellular carcinoma

(2008) Zhi-Ming Liu et al.   CANCER LETTERS

Protection Against Aflatoxin B1-Induced Cytotoxicity by Expression of the Cloned Aflatoxin B1-Aldehyde Reductases Rat AKR7A1 and Human AKR7A3

(2008) Sridevi Bodreddigari et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Quantification of Urinary Aflatoxin B1Dialdehyde Metabolites Formed by Aflatoxin Aldehyde Reductase Using Isotope Dilution Tandem Mass Spectrometry

(2008) Denise N. Johnson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Butylated hydroxytoluene chemoprevention of aflatoxicosis – Effects on aflatoxin B1 bioavailability, hepatic DNA adduct formation, and biliary excretion

(2008) J.A. Guarisco et al.   FOOD AND CHEMICAL TOXICOLOGY

Mutagenicity of tamoxifen DNA adducts in human endometrial cells and in silico prediction of p53 mutation hotspots

(2008) E. Liapis et al.   NUCLEIC ACIDS RESEARCH

Quantifiable mRNA transcripts for tamoxifen-metabolising enzymes in human endometrium

(2008) Maneesh N. Singh et al.   TOXICOLOGY

Discriminating the molecular basis of hepatotoxicity using the large-scale characteristic molecular signatures of toxicants by expression profiling analysis

(2008) Jung Woo Eun et al.   TOXICOLOGY

Biomarkers in Toxicology and Risk Assessment: Informing Critical Dose–Response Relationships

(2007) James A. Swenberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Polymorphism of XRCC1 and the frequency of mutation in codon 249 of thep53 gene in hepatocellular carcinoma among guangxi population, China

(2007) Xi Dai Long et al.   MOLECULAR CARCINOGENESIS