Article
Materials Science, Multidisciplinary
Ozge Varlik, Yapincak Goncu, A. Y. Nuran
Summary: Titanium diboride-chitosan composite coatings were successfully produced by electrophoretic deposition techniques. The effect of process parameters on the coatings was investigated and the suspension properties and deposition mechanism were discussed. The results showed that the coatings had a uniform and crack-free morphology, and the chitosan content significantly affected the adhesion behavior.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Materials Science, Multidisciplinary
Arman Molaei, MardAli Yousefpour
Summary: Composite coatings of chitosan-bioglass-hydroxyapatite-halloysite nanotube were successfully produced by electrophoretic deposition, demonstrating good corrosion resistance and apatite-inducing ability in corrected simulated body fluid.
Article
Materials Science, Coatings & Films
Sandeep Singh, Gurpreet Singh, Niraj Bala
Summary: The study fabricated a composite coating of CS-HA-BG-Fe3O4 with bioactivity, high corrosion resistance, and excellent cell proliferation, suitable for biomedical applications.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Applied
Mengna Tian, Zhangfei Lin, Wenyan Tang, Wenpeng Wu, Li Wang, Jinglai Zhang
Summary: Electrophoretic deposition was used to prepare bioactive glass-chitosan coating loaded with tetracycline on AZ31B magnesium alloy. The coating exhibited improved corrosion resistance, antibacterial activity, and osteogenic induction properties. It has potential for application in medical devices and bone implant materials.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Biochemistry & Molecular Biology
Ezgi Kizilkonca, Emrah Torlak, F. Bedia Erim
Summary: The effects of cerium oxide nanoparticles on chitosan-based films were investigated, showing enhanced antibacterial activity. These composite films, based on chitosan, exhibit flexibility, antibacterial efficacy, and good mechanical strength, making them suitable for packaging or coating materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
C. Zanca, S. Carbone, B. Patella, F. Lopresti, G. Aiello, V Brucato, F. Carfi Pavia, V La Carrubba, R. Inguanta
Summary: In this study, composite coatings of chitosan and silver nanoparticles were developed as antibacterial coatings for orthopedic implants. The coatings were deposited on AISI 304L using the galvanic deposition method. Physical-chemical characterizations showed that the coatings had uniform and porous surface structures with incorporated silver nanoparticles. Corrosion tests demonstrated improved corrosion protection compared to the bare AISI 304L. The ability of the coating to release silver ions in the simulated body fluid was also evaluated and showed a switch in release mechanism after 3 hours.
Article
Polymer Science
Arash Ghalayani Esfahani, Maria Sartori, Chiara Bregoli, Jacopo Fiocchi, Carlo Alberto Biffi, Ausonio Tuissi, Gianluca Giavaresi, Alessandro Presentato, Rosa Alduina, Angela De Luca, Alessia Cabrini, Cristina De Capitani, Milena Fini, Emanuele Gruppioni, Marino Lavorgna, Alfredo Ronca
Summary: Prosthetic reconstruction can provide functional and aesthetic benefits to individuals with hand and finger injuries. This study developed a new silver-doped chitosan coating as a potential solution for infection therapy. The coatings exhibited impressive biological and physical properties.
Article
Materials Science, Multidisciplinary
Elisa Zanchi, Antonio Gianfranco Sabato, Mari Carmen Monterde, Lucile Bernadet, Marc Torrell, Jose Antonio Calero, Albert Tarancon, Federico Smeacetto
Summary: Developing cost-effective and durable interconnects is crucial for commercializing solid oxide cells. This study reviews and discusses the microstructural and electrical characteristics of MnCo2O4 spinel coatings on ferritic stainless steel using electrophoretic deposition. The results show improved performance and durability with a low cost, making it a promising approach for complex-shaped interconnects.
MATERIALS & DESIGN
(2023)
Article
Materials Science, Multidisciplinary
Jun Zhang, Shaojun Chu, Weiliang Jin, Fei Cai, Hongmin Zhu, Saijun Xiao
Summary: This paper presents a novel process for preparing TiB2 coatings by synthesizing TiB2 nanoparticles and subsequent electrophoretic deposition. The thickness of the coatings increased with the rise of cell voltages, and the hardness and elastic modulus values also increased with elevated electrophoretic voltages.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Materials Science, Ceramics
Jie Pang, Qian Kou, Chuntao Ge, Lingling Xie, Weiliang Jin, Wenjuan Qi, Jun Zhang, Hongmin Zhu, Saijun Xiao
Summary: A novel method for preparing ZrB2 coatings by combining molten salt synthesis of ZrB2 nanoparticles and subsequent electrophoretic deposition has been proposed. Nanoscale ZrB2 particles were produced by borothermal reduction of ZrO2, and then deposited onto graphite substrates using electrophoretic deposition in the same molten system. The prepared ZrB2 coatings exhibited good high-temperature oxidation resistance.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2023)
Article
Chemistry, Applied
Sandeep Singh, Gurpreet Singh, Niraj Bala
Summary: In this study, iron oxide particles were combined with hydroxyapatite to produce a coating that enhanced the antimicrobial and bioactive properties of magnesium implants. The composite coating was found to be blood compatible and could potentially be widely utilized in biomedical implant applications.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Materials Science, Ceramics
R. Askarnia, S. Roueini Fardi, M. Sobhani, H. Staji
Summary: Ternary HA/chitosan/graphene oxide (GO) coating was successfully deposited on AZ91D magnesium alloy as bone implants. The addition of GO resulted in increased hardness, improved HA growth, decreased corrosion rate, and enhanced antibacterial properties of the composite coatings.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Coatings & Films
Muhammad Asim Akhtar, Camilla E. Mariotti, Bice Conti, Aldo R. Boccaccini
Summary: In this study, chitosan-bioactive glass-ferulic acid composite coatings were successfully fabricated using AC-EPD technique. The coatings exhibited good biocompatibility and antibacterial properties, enhancing the viability of MG-63 human osteoblast-like cells. Furthermore, the coatings formed a hydroxyapatite surface layer after incubation in simulated body fluid.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Physical
Hyeri Kang, Yoonsu Park, Yun-Kun Hong, Songhun Yoon, Min-Ho Lee, Don-Hyung Ha
Summary: This study investigates the influence of different solvent ratios (hexane, toluene, and chloroform) on charge formation in EPD systems. The results show that increasing the ratio of toluene to hexane leads to thicker and rougher NP films, while increasing the ratio of chloroform to hexane reduces film thickness significantly. Solvent choice plays a key role in determining the morphology and processability of NP films fabricated via EPD.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Physical
Ahmad Saadati, Behnam Nourmohammadi Khiarak, Ayda Asaadi Zahraei, Aida Nourbakhsh, Hurieh Mohammadzadeh
Summary: In this study, magnesium alloys were coated with hydroxyapatite/chitosan using electrophoretic deposition method with different graphene oxide content. It was found that adding 1% graphene oxide and applying 150V potential significantly improved the corrosion resistance of the magnesium alloys. The microstructure of the coatings showed a significant relationship with their corrosion resistance, potentially due to the formation of well dispersed, low porosity, and relatively dense composite coatings.
SURFACES AND INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Waseem Kitana, Indra Apsite, Jonas Hazur, Aldo R. Boccaccini, Leonid Ionov
Summary: This study reports a 4D biofabrication-based concept for the fabrication of a T-shaped vascular bifurcation using 3D printed shape-changing layers. The tubular structures with various diameters were formed by controlling the parameters precisely. The fabricated T-junction showed minimal leakages and supported excellent cell growth. This approach has the potential to fabricate fully automatic self-actuated vascular bifurcations.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Engineering, Biomedical
Ana Paula Nogueira Alves, Marcela Arango-Ospina, Rodrigo Luiz Moraes Saldanha Oliveira, Igor Maia Ferreira, Elisangela Guzi de Moraes, Malte Hartmann, Antonio Pedro Novaes de Oliveira, Aldo Roberto Boccaccini, Eliandra de Sousa Triches
Summary: Bone infection is a major challenge in orthopedics, and 3D printing can produce customized scaffolds to stimulate bone growth. The combination of bioceramics with tea tree oil as an antimicrobial agent shows potential for tissue growth stimulation and infection treatment. Coating the 3D-printed beta-TCP/S53P4 BG scaffolds with gelatin/tea tree oil exhibits good antibacterial activity and cell viability.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2023)
Article
Engineering, Biomedical
A. Weizel, T. Distler, R. Detsch, A. R. Boccaccini, H. Seitz, S. Budday
Summary: Numerical simulations using appropriate material models and parameters are valuable for understanding the effects of mechanical stimulation on hydrogels for cartilage replacement. In this study, hyperviscoelastic material parameters for human articular cartilage and two replacement materials were identified using COMSOL Multiphysics (R) v. 5.6. The results revealed that ADA-GEL and ChondroFiller(liquid) exhibit faster stress relaxation and lower relaxation time constants compared to cartilage. Additionally, ADA-GEL and ChondroFiller(liquid) have a predominant elastic response, while cartilage has a predominant viscoelastic response.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Review
Engineering, Biomedical
Oznur Demir-Oguz, Aldo R. Boccaccini, Dagnija Loca
Summary: Calcium phosphate bone cements (CPCs) have valuable properties such as bioactivity, osteoconductivity, injectability, and moldability, but their low mechanical performance limits their clinical application. Adding bioactive glasses (BGs) as a secondary powder phase can improve the injectable properties of CPCs and enhance the degradation rate, in vitro osteogenic differentiation, cell response, and tissue-material interaction.
BIOACTIVE MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Baiyan Sui, Zhiyan Xu, Zhiyu Xue, Yong Xiang, Tian Zhou, Ana M. Beltraïn, Kai Zheng, Xin Liu, Aldo R. Boccaccini
Summary: A postgrafting strategy mediated by polydopamine (PDA) coating is proposed to incorporate different metal elements into mesoporous silicate bioactive glass nanoparticles (MBG NPs) while maintaining their stability. However, the PDA coating reduces the ion-binding free energy of MBG NPs for calcium and phosphate ions, resulting in minimal deposition of calcium phosphate clusters on the PDA@MBG NP surface after immersion in simulated body fluid for 7 days, indicating a lack of hydroxyapatite mineralization.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Mahshid Monavari, Shahin Homaeigohar, Rucha Medhekar, Qaisar Nawaz, Mehran Monavari, Kai Zheng, Aldo R. Boccaccini
Summary: In this study, a wound dressing composed of an alginate dialdehyde-gelatin (ADA-GEL) hydrogel incorporated by astaxanthin (ASX) and 70B borate bioactive glass (BBG) microparticles was developed through 3D printing. The composite hydrogel construct, stiffened by ASX and BBG particles, showed prolonged degradation and steady release of ASX, promoting cell adhesion, proliferation, and migration for faster wound healing.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Engineering, Biomedical
Florencia Diaz, Nicholas Forsyth, Aldo R. Boccaccini
Summary: This review evaluates the work done in the last decade toward the production of aligned pore structures by AIT, focusing on optimizing the biomechanical properties by modifying the pore structure, categorizing by material type and application. The review also discusses related topics including growth factor incorporation, drug delivery applications, and immune system response studies.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Polymer Science
Arturo E. Aguilar-Rabiela, Shahin Homaeigohar, Eduin I. Gonzalez-Castillo, Mirna L. Sanchez, Aldo R. Boccaccini
Summary: Composite biomaterials combining different biomaterials with unequal release rates have shown potential for drug delivery applications. In this study, mesoporous bioactive glass nanoparticles (MBGN) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microspheres loaded with Astaxanthin (ASX) were synthesized and compared in terms of ASX release kinetic, ASX entrapment efficiency, and cell viability. The release behavior could be fine-tuned by adjusting the MBGN content in the composite particles, and the composite microspheres exhibited a more prolonged release profile with sustained cytocompatibility.
Article
Chemistry, Analytical
Uwe Frank, Jana Dienstbier, Florentin Tischer, Simon E. E. Wawra, Lukas Gromotka, Johannes Walter, Frauke Liers, Wolfgang Peukert
Summary: The increasing complexity in particle science and technology requires the ability to deal with multidimensional property distributions. We present the theoretical background for multidimensional fractionations by transferring the concepts known from one dimensional to higher dimensional separations. Examples of technical realizations for shape-selective separation in a hydrocyclone and for density-selective separation in a disc separator are given.
Article
Materials Science, Ceramics
Fatih E. Bastan, Behlul Sen, Sule Ozgenc, Ana M. Beltran, Aldo R. Boccacini
Summary: In recent years, the morphology of nanoparticles has been modified to optimize their specific properties for various applications. Plate-like particles that mimic the microstructure of nacre have shown exceptional mechanical performance. However, creating equiaxed hydroxyapatite (HA) plates with an oriented architecture remains a significant challenge.
CERAMICS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Marta Clerici, Vera Citro, Amy L. Byrne, Tina P. Dale, Aldo R. Boccaccini, Giovanna Della Porta, Nicola Maffulli, Nicholas R. Forsyth
Summary: By comparing and contrasting different tendon cell populations, this study found that type II tendon stem cells (TSCs) are the most promising population for expansion due to their enhanced proliferative potential, multipotency, and maintenance of a tendon-specific profile. Furthermore, physoxia promotes enhanced proliferation and maintenance of a tenogenic profile in all tendon-derived cell populations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biotechnology & Applied Microbiology
Yuyun Yang, Yuejun Liu, Laiming Song, Xiufang Cui, Juncen Zhou, Guo Jin, Aldo R. Boccaccini, Sannakaisa Virtanen
Summary: Iron-oxide-based biomagnetic nanocomposites have significant potential for biomedical applications such as MRI and cancer treatment. By modifying their properties and structure, their performance can be optimized. However, rigorous evaluation of their biosafety is needed before clinical translation.
TRENDS IN BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Jana Schulik, Sahar Salehi, Aldo R. Boccaccini, Stefan Schruefer, Dirk W. Schubert, Andreas Arkudas, Annika Kengelbach-Weigand, Raymund E. Horch, Rafael Schmid
Summary: This study compared the mechanical properties and the behavior of human umbilical vein endothelial cells (HUVECs) in three hydrogels (Alg/HA/Gel, ADA-GEL, and GelMA) for vascular tissue engineering. ADA-GEL and GelMA showed promising results for cell survival, migration, and sprouting, while Alg/HA/Gel did not provide a good environment for long-term survival of HUVECs.
BIOENGINEERING-BASEL
(2023)
Article
Nanoscience & Nanotechnology
Shahin Homaeigohar, Mhd Adel Assad, Amir Hossein Azari, Farnaz Ghorbani, Chloe Rodgers, Matthew J. Dalby, Kai Zheng, Rongyao Xu, Mady Elbahri, Aldo. R. Boccaccini
Summary: The biohybrid nanofibers developed in this study can stimulate the adhesion and proliferation of fibroblast and endothelial cells, showing potential for promoting wound healing and antibacterial activity.
ACS APPLIED BIO MATERIALS
(2023)
Article
Materials Science, Ceramics
Susanta Sengupta, Liliana Liverani, Dusan Galusek, Aldo R. Boccaccini
Summary: Borosilicate glass fibers fabricated by electrospinning in combination with sol-gel processing showed good bioactivity and non-cytotoxic nature in simulated body fluid.
