Journal
CRITICAL REVIEWS IN BIOTECHNOLOGY
Volume 32, Issue 3, Pages 218-234Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/07388551.2011.604838
Keywords
Sulforaphane; glucoraphanin; chemoprevention; purification; analysis; bioactivity; antioxidant; anticarcinogenic; anti-inflammatory
Categories
Funding
- National Natural Fund of China [20806005]
- Chinese Universities Scientific Fund [ZZ1025]
Ask authors/readers for more resources
Epidemiological data show that a diet rich in fruits and vegetables can reduce the risk from a number of cancers and chronic diseases. Sulforaphane (SF), a phytochemical constituent of cruciferous vegetables, has been widely researched in recent decades as a potential chemopreventive compound. Nonexistent in intact vegetables, natural SF, is formed from glucoraphanin hydrolyzed by myrosinase. This review summarizes and compares different analysis, isolation and purification methods engaged in SF research. Major important chemopreventive properties of SF investigated in existing research are reviewed and discussed, including antioxidant, anticarcinogenic and anti-inflammatory functions. Considering the potential applications of SF in the future, metabolism, stability and formulation developments of SF are also discussed. Research opportunities are identified based on the review of existing studies to facilitate future explorations on SF, a promising natural compound in chemopreventive therapy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available