Regulation of p53 - insights into a complex process

Influence of tetramerisation on site-specific post-translational modifications of p53: comparison of human and murine p53 tumour suppressor protein.

(2010) Lorna Jane Warnock et al.   CANCER BIOLOGY & THERAPY

Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation†

(2009) Lisa M. Miller Jenkins et al.   BIOCHEMISTRY

Tpl-2 kinase downregulates the activity of p53 and enhances signaling pathways leading to activation of activator protein 1 induced by EGF

(2009) P. Khanal et al.   CARCINOGENESIS

FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53

(2009) Anna Maria Ochocka et al.   FEBS LETTERS

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis

(2009) Chunyan Tian et al.   NATURE CELL BIOLOGY

Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP

(2009) Yifeng Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thymine–DNA glycosylase interacts with and functions as a coactivator of p53 family proteins

(2008) Eun-Joo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

14-3-3  Down-regulates p53 in Mammary Epithelial Cells and Confers Luminal Filling

(2008) C. G. Danes et al.   CANCER RESEARCH

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Proteasome activator PA28γ regulates p53 by enhancing its MDM2-mediated degradation

(2008) Zhuo Zhang et al.   EMBO JOURNAL

The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2–DAXX–HAUSP complex

(2008) Min Sup Song et al.   EMBO JOURNAL

RYBP stabilizes p53 by modulating MDM2

(2008) Deng Chen et al.   EMBO REPORTS

Critical Role of Cysteine Residue 81 of Macrophage Migration Inhibitory Factor (MIF) in MIF-induced Inhibition of p53 Activity

(2008) Haiyoung Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MSL2 Promotes Mdm2-independent Cytoplasmic Localization of p53

(2008) Jan-Philipp Kruse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role for 53BP1 Tudor Domain Recognition of p53 Dimethylated at Lysine 382 in DNA Damage Signaling

(2008) Ioulia Kachirskaia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycophenolic Acid Activation of p53 Requires Ribosomal Proteins L5 and L11

(2008) Xiao-Xin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of ANKRD11 as a p53 coactivator

(2008) P. M. Neilsen et al.   JOURNAL OF CELL SCIENCE

Necdin Regulates p53 Acetylation via Sirtuin1 to Modulate DNA Damage Response in Cortical Neurons

(2008) K. Hasegawa et al.   JOURNAL OF NEUROSCIENCE

Aberrant Expression of Nucleostemin Activates p53 and Induces Cell Cycle Arrest via Inhibition of MDM2

(2008) M.-S. Dai et al.   MOLECULAR AND CELLULAR BIOLOGY

Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage

(2008) A. M. Gamper et al.   MOLECULAR AND CELLULAR BIOLOGY

Mdm2 and Mdm4 Loss Regulates Distinct p53 Activities

(2008) J. A. Barboza et al.   MOLECULAR CANCER RESEARCH

Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

(2008) Ssang-Taek Lim et al.   MOLECULAR CELL

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

(2008) Yaara Ofir-Rosenfeld et al.   MOLECULAR CELL

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

(2008) Julia K. Kurash et al.   MOLECULAR CELL

Arginine methylation regulates the p53 response

(2008) Martin Jansson et al.   NATURE CELL BIOLOGY

Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax

(2008) S. Patel et al.   NUCLEIC ACIDS RESEARCH

14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers

(2008) S. Rajagopalan et al.   NUCLEIC ACIDS RESEARCH

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

(2008) H F Horn et al.   ONCOGENE

PML enhances the regulation of p53 by CK1 in response to DNA damage

(2008) O Alsheich-Bartok et al.   ONCOGENE

Twist and p53 reciprocally regulate target genes via direct interaction

(2008) M Shiota et al.   ONCOGENE

Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage

(2008) X. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2

(2008) Y. Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK

(2008) K. A. Boehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53

(2008) J. M. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Recognition of Phosphorylated Transactivation Domains of p53 by Different p300 Domains

(2007) Smarajit Polley et al.   JOURNAL OF MOLECULAR BIOLOGY