Article
Medicine, General & Internal
Raja M. Chinthamuneedi, Sandeep Phaltane, Meher P. Chinthamuneedi, Srinivas Kondalsamy-Chennakesavan, Benjamin K. Cheung
Summary: This study evaluated the effectiveness of modifications to rapid response team (RRT) activation criteria in preventing RRT activation and the impact on adverse events caused by treatment delays. The results showed that modifications to criteria did not affect the rate of RRT activation but had detrimental effects on patient safety, particularly in medical patients.
INTERNAL MEDICINE JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Qiuxia Zhang, Khuan Lee, Zawiah Mansor, Iskasymar Ismail, Yi Guo, Qiao Xiao, Poh Ying Lim
Summary: This study conducted a systematic review to understand the effect of rapid response teams (RRT) on patient outcomes. The results showed that, despite variation in context and intervention type, most studies demonstrated that RRT positively impacts patient outcomes.
Article
Critical Care Medicine
Quelly Mae Rivadillo Ramos, Ki Hong Kim, Jeong Ho Park, Sang Do Shin, Kyoung Jun Song, Ki Jeong Hong
Summary: This study found that in out-of-hospital cardiac arrest (OHCA) patients in Korea, those with lower socioeconomic status were associated with longer emergency medical service (EMS) response times and lower rates of dual dispatch response.
Article
Emergency Medicine
Tae Han Kim, Jin Hee Jung, Kyoung Jun Song, Ki Jeong Hong, Joo Jeong, Stephen Gyung Won Lee
Summary: This study evaluated the association between pediatric age and dispatcher recognition in out-of-hospital cardiac arrest (OHCA) cases. The findings showed that patients aged 7-18 years old had a lower rate of cardiac arrest recognition and dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) instruction provision compared to those under one year old. It suggests the importance of developing tailored protocols based on age and cause of arrest to improve dispatcher performance in pediatric OHCA cases.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Multidisciplinary Sciences
Ahmed N. Balshi, Mohammed A. Al-Odat, Abdulrahman M. Alharthy, Rayan A. Alshaya, Hanan M. Alenzi, Alhadzia S. Dambung, Huda Mhawish, Saad M. Altamimi, Waleed Th. Aletreby
Summary: Automated activation of the RRT significantly reduced CPR events and rates, improved CPR success rate, reduced hospital length of stay and mortality, but increased the number of RRT activations. There were no differences in unplanned ICU admission or readmission.
Article
Multidisciplinary Sciences
Lorena Micheline Alves Silva, Diego Marques Moroco, Jose Paulo Pintya, Carlos Henrique Miranda
Summary: Implementing a rapid response team (RRT) triggered by the modified early warning score (MEWS) in high-risk wards offering ED support is associated with decreased in-hospital mortality rate, as observed in this study.
Article
Public, Environmental & Occupational Health
Jianing Xu, Xuejie Dong, Hongfan Yin, Zhouyu Guan, Zhenghao Li, Fangge Qu, Tian Chen, Caifeng Wang, Qiong Fang, Lin Zhang
Summary: The study designed an innovative team-based CPR educational plan to improve team collaboration and resuscitation quality. The training significantly improved teamwork performance and CPR operation skills.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Timothy Morgenthaler, Emily A. Linginfelter, Peter C. Gay, Sandra E. Anderson, Daniel Herold, Virginia Brown, Joseph M. Nienow
Summary: As more patients rely on mechanical or electronic technologies for treatment, medical device recalls can have significant impacts on patients, causing anxiety, extra costs, and interruptions of care. Having an established and well-organized medical device recall plan in place allows for a rapid and effective response, reducing the burden on healthcare providers and alleviating patient anxiety through clear communication.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2022)
Review
Nursing
Stephanie K. Sprogis, Judy Currey, Daryl Jones, Julie Considine
Summary: This review explores the use of the pre-Medical Emergency Team tier of Rapid Response Systems in recognizing and responding to early clinical deterioration in adult ward patients. Findings suggest that there is disparity between clinical practice and pre-MET escalation protocols, and there is a need for further research to understand barriers and facilitators influencing the use of pre-MET strategies targeted at patient deterioration.
INTENSIVE AND CRITICAL CARE NURSING
(2021)
Article
Critical Care Medicine
Stephanie K. Sprogis, Judy Currey, Daryl Jones, Julie Considine
Summary: The study aimed to describe the structure and processes of the pre-MET RRS tier in an acute care setting. Findings revealed that while the structures and processes were largely consistent with national guidelines, there were internal inconsistencies in preMET activation criteria and unclear recommendations for modifying criteria.
AUSTRALIAN CRITICAL CARE
(2021)
Article
Critical Care Medicine
Stephanie K. Sprogis, Judy Currey, Daryl Jones, Julie Considine
Summary: This study aimed to explore clinicians' use of the pre-MET tier. Observations identified multiple gaps between pre-MET policy and clinicians' use, highlighting the need for optimization and addressing system-based barriers to recognizing and responding to pre-MET deterioration.
AUSTRALIAN CRITICAL CARE
(2023)
Article
Critical Care Medicine
Justin Yap, Morgan Haines, Armin Nowroozpoor, Richard Armour, Allessandra Luongo, Gurwinder Sidhu, Frank Scheuermeyer, Jacob Hutton, Jennie Helmer, Jennifer Bolster, Joseph Puyat, Jim Christenson, Brian Grunau
Summary: This study investigated the reasons for non-treatment of out-of-hospital cardiac arrests (OHCA) by emergency medical services (EMS) and found that a prolonged interval from the event until EMS assessment was the predominant reason for withholding treatment. Additionally, a proportion of OHCAs involved illicit drug use.
Article
Critical Care Medicine
Stephanie K. Sprogis, Maryann Street, Judy Currey, Daryl Jones, Evan Newnham, Julie Considine
Summary: This study found that modifications to MET activation criteria were infrequent and not associated with negative patient safety outcomes, based on a retrospective medical record audit of inpatients admitted to two acute-care hospitals in Melbourne, Australia.
AUSTRALIAN CRITICAL CARE
(2021)
Article
Emergency Medicine
Osman Adi, Muhammad Faiz Baherin, Chan Pei Fong, Ahmad AbdulBasitz Ahmad Fatan, Azma Haryaty Ahmad, Alhady Alfian Yusof, Faheem Ahmed Khan
Summary: This article reports three cases of cardiac arrest due to foreign body airway obstruction (FBAO), where prompt flexible bronchoscopy was performed to confirm the diagnosis and retrieve the foreign body, leading to immediate improvements in oxygenation and ventilation.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Review
Emergency Medicine
David B. Crabb, Yasmeen O. Elmelige, Zoe C. Gibson, Daniel C. Ralston, Caleb Harrell, Scott A. Cohen, Desmond E. Fitzpatrick, Torben K. Becker
Summary: Immediate recognition of out-of-hospital cardiac arrest (OHCA) is crucial for timely initiation of T-CPR. The study found difficulty in communicating the patient's respiratory status as the main reason for EMD's lack of recognition of OHCA. It is recommended to enhance the identification of respiratory issues in unconscious patients in EMD training and algorithms.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Letter
Dermatology
Darrell S. Rigel, John W. Whitaker, Maral K. Skelsey, Gary Peck, Michael D. Howell, Burkhard Jansen
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2022)
Article
Anesthesiology
Simon T. Dillon, Hasan H. Otu, Long H. Ngo, Tamara G. Fong, Sarinnapha M. Vasunilashorn, Zhongcong Xie, Lisa J. Kunze, Kamen V. Vlassakov, Ayesha Abdeen, Jeffrey K. Lange, Brandon E. Earp, Zara R. Cooper, Eva M. Schmitt, Steven E. Arnold, Tammy T. Hshieh, Richard N. Jones, Sharon K. Inouye, Edward R. Marcantonio, Towia A. Libermann
Summary: Using SOMAscan assay, this study identifies acute and longer-term proteome changes associated with surgery in plasma and cerebrospinal fluid (CSF) in older patients. The findings suggest potential biomarkers for neuroinflammation and provide insights into the neuroinflammatory response to surgery.
ANESTHESIA AND ANALGESIA
(2023)
Article
Anesthesiology
Matthew S. Duprey, John W. Devlin, John L. Griffith, Thomas G. Travison, Becky A. Briesacher, Richard Jones, Jane S. Saczynski, Eva M. Schmitt, Yun Gou, Edward R. Marcantonio, Sharon K. Inouye
Summary: This study aimed to evaluate the association between medication use and postoperative delirium and postoperative neurocognitive disorder (PND) in older adults undergoing major elective surgery. The results showed that administration of benzodiazepines to older adults hospitalized after major surgery is associated with increased postoperative delirium.
ANESTHESIA AND ANALGESIA
(2022)
Article
Neuroimaging
Michele Cavallari, Tamara G. Fong, Alexandra Touroutoglou, Bradford C. Dickerson, Eva Schmitt, Thomas G. Travison, Edward R. Marcantonio, Long H. Ngo, Towia Libermann, Alvaro Pascual-Leone, Mouhsin M. Shafi, Sharon K. Inouye, Richard N. Jones
Summary: Neuroimaging studies conducted in small samples of voluntary participants may lead to selection bias. This study investigated the impact of postoperative delirium on long-term cognitive decline in older surgical patients, observing a discrepancy in the effect based on MRI participation.
BRAIN IMAGING AND BEHAVIOR
(2022)
Article
Anesthesiology
John G. Gaudet, Corey Kull, Marc L. Eskenazi, John Diaper, Julien Maillard, Florence Mollard, Christophe Marti, Edward R. Marcantonio, Delphine S. Courvoisier, Bernhard Walder
Summary: In this study, the English version of the 3D-CAM instrument was translated into French and adapted for older high-risk patients. Through qualitative and quantitative evaluations during the translation and adaptation process, the researchers confirmed the intended purpose and applicability of the questionnaire. Adjustments were made to ensure the clarity and acceptability of the questionnaire among patients and caregivers.
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2022)
Article
Health Care Sciences & Services
Timothy S. Anderson, Edward R. Marcantonio, Ellen P. McCarthy, Long Ngo, Mara A. Schonberg, Shoshana J. Herzig
Summary: Diagnosed dementia is associated with a significant increase in the risk of mortality within 30 days of discharge and a slight increase in the risk of readmission. Dementia patients discharged to the community face a greater risk of adverse outcomes, indicating possible issues in post-discharge care services and caregiver support.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Geriatrics & Gerontology
Tammy T. Hshieh, Eva M. Schmitt, Tamara G. Fong, Steve Arnold, Michele Cavallari, Bradford C. Dickerson, Simon T. Dillon, Richard N. Jones, Towia A. Libermann, Edward R. Marcantonio, Alvaro Pascual-Leone, Mouhsin M. Shafi, Alexandra Touroutoglou, Thomas G. Travison, Ray Yun Gou, Douglas Tommet, Ayesha Abdeen, Brandon Earp, Lisa Kunze, Jeffrey Lange, Kamen Vlassakov, Sharon K. Inouye
Summary: The SAGES II study aims to enhance our understanding of the correlation between delirium and dementia by examining various biomarkers in older adults undergoing major surgery. The study utilizes a range of assessment methods and techniques, including cognitive testing, neuroimaging, and neurophysiology. This study provides valuable insights into the relationship between delirium and dementia.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Jessica M. Ross, Emiliano Santarnecchi, Shu Jing Lian, Tamara G. Fong, Alexandra Touroutoglou, Michele Cavallari, Thomas G. Travison, Edward R. Marcantonio, Towia A. Libermann, Eva M. Schmitt, Sharon K. Inouye, Mouhsin M. Shafi, Alvaro Pascual-Leone
Summary: Post-surgical delirium is a serious complication that can lead to cognitive decline and loss of function. This study found that neurophysiologic measures, such as resting-state EEG and transcranial magnetic stimulation, could predict the risk of delirium in older patients undergoing surgery.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Franchesca Arias, Fan Chen, Haley Shiff, Edward R. Marcantonio, Richard N. Jones, Eva M. Schmitt, Eran Metzger, Tamara G. Fong, Thomas G. Travison, Sharon K. Inouye
Summary: The study found that higher paternal education was associated with lower incidence and severity of postoperative delirium, while higher maternal education was related to lower delirium incidence but did not reach statistical significance. The effect of paternal education on delirium incidence was independent of other patient characteristics, suggesting that examining early-life exposures may provide unique insights into the risks and pathogenesis of delirium.
CLINICAL GERONTOLOGIST
(2023)
Article
Clinical Neurology
Tammy T. Hshieh, Ray Yun Gou, Richard N. Jones, Douglas L. Leslie, Edward R. Marcantonio, Guoquan Xu, Thomas G. Travison, Tamara G. Fong, Eva M. Schmitt, Sharon K. Inouye
Summary: This study examines the healthcare costs associated with delirium in older hospitalized patients with and without Alzheimer's disease and related dementias (ADRD). The findings show that patients with ADRD are more likely to develop delirium and have higher costs associated with delirium compared to non-ADRD patients. The costs increase progressively over the course of one year for ADRD patients, while the increase is consistent across time periods for non-ADRD patients.
ALZHEIMERS & DEMENTIA
(2023)
Letter
Geriatrics & Gerontology
Ashley Kuzmik, John Hannan, Marie Boltz, Priyanka Shrestha, Erica K. K. Husser, Donna M. M. Fick, Edward R. R. Marcantonio
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Medicine, General & Internal
Timothy S. S. Anderson, Shoshana J. J. Herzig, Bocheng Jing, W. John Boscardin, Kathy Fung, Edward R. R. Marcantonio, Michael A. A. Steinman
Summary: This study found that intensive pharmacologic antihypertensive treatment was associated with a greater risk of adverse events among hospitalized older adults with elevated blood pressures. These findings do not support the treatment of elevated inpatient blood pressures without evidence of end organ damage, and highlight the need for randomized clinical trials of inpatient blood pressure treatment targets.
JAMA INTERNAL MEDICINE
(2023)
Meeting Abstract
Dermatology
Lidia Sans-De San Nicolas, Ignasi Figueras-Nart, Montserrat Bonfill-Orti, Carmen De Jesus-Gil, Irene Garcia-Jimenez, Antonio Guilabert-Vidal, Laia Curto-Barredo, Marta Bertolin-Colilla, Marta Ferran, Esther Serra-Baldrich, Anna Zalewska-Janowska, Yui-Hsi Wang, Michael D. Howell, Ramon M. Pujol, Luis F. Santamaria-Babi
ACTA DERMATO-VENEREOLOGICA
(2022)
Letter
Dermatology
Pearl E. Grimes, Jag Bhawan, Michael D. Howell, Seemal Desai, Edna Coryell, Rama Nashawati, Michael Einziger, Ann Marie Simpson, Alex Yaroshinsky, Tim Mc Craw
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Meeting Abstract
Dermatology
Michael D. Howell, Ramesh Ratnappan, Talisha Allen, James Rock, John W. Whitaker
BRITISH JOURNAL OF DERMATOLOGY
(2022)