IRAK1 functional genetic variant affects severity of septic shock*

The HapMap and Genome-Wide Association Studies in Diagnosis and Therapy

(2009) Teri A. Manolio et al.   Annual Review of Medicine

Phase 2 trial of eritoran tetrasodium (E5564), a Toll-like receptor 4 antagonist, in patients with severe sepsis*

(2009) Mark Tidswell et al.   CRITICAL CARE MEDICINE

IRAK-4 Inhibitors for Inflammation

(2009) Zhulun Wang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells

(2009) Kyung W. Song et al.   MOLECULAR IMMUNOLOGY

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit*

(2008) Liesbet Henckaerts et al.   CRITICAL CARE MEDICINE

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Association of Interacting Genes in the Toll-Like Receptor Signaling Pathway and the Antibody Response to Pertussis Vaccination

(2008) Tjeerd G. Kimman et al.   PLoS One

IRAK1: A critical signaling mediator of innate immunity

(2007) Sridevi Gottipati et al.   CELLULAR SIGNALLING