Article
Clinical Neurology
Michela Prete, Nicola Cellini, Lucia Ronconi, Elisa Di Rosa
Summary: This study aimed to investigate the moderating role of Cognitive Reserve (CR) in the relationship between sleep difficulties and cognitive performance in patients with Parkinson's disease (PD). The results showed a significant negative correlation between sleep quality and cognitive performance, and CR was found to moderate the negative association between REM sleep behavior disorder (RBD) and executive functions. Patients with low levels of CR were more at risk of developing cognitive deficits in the presence of sleep difficulties.
Article
Health Care Sciences & Services
Jolie D. D. Barter, Dwaina Thomas, Liang Ni, Allison A. A. Bay, Theodore M. M. Johnson, Todd Prusin, Madeleine E. E. Hackney
Summary: Understanding the effects of multimorbidity on motor and cognitive function is important for tailoring therapies. This study found that individuals with comorbid Parkinson's disease (PD) and diabetes mellitus (DM) had poorer functional ability compared to individuals with only PD or DM. Both PD and DM independently had adverse effects on motor function, and comorbid PD+DM further impaired attention, highlighting the importance of attention-focused therapies.
Article
Medicine, General & Internal
Francesca Borgnis, Francesca Baglio, Elisa Pedroli, Federica Rossetto, Mario Meloni, Giuseppe Riva, Pietro Cipresso
Summary: In this study, the researchers developed a tool called EXIT 360 degrees for assessing executive functioning in Parkinson's Disease patients. The results showed that the tool was usable and provided a positive user experience. Patients considered it to be ecologically valid and engaging.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Neurosciences
Eduardo Inacio Nascimento Andrade, Christina Manxhari, Kara M. Smith
Summary: This study aimed to evaluate the relative contributions of cognitive and motor dysfunction to action verb production in patients with Parkinson's Disease (PD). The results showed that pausing before action-related language is associated with cognitive dysfunction, and may serve as a marker of mild cognitive impairment in PD.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Biology
Paolo Solla, Carla Masala, Tommaso Ercoli, Claudia Frau, Caterina Bagella, Ilenia Pinna, Francesco Loy, Giovanni Defazio
Summary: Olfactory and cognitive disorders are important non-motor symptoms in Parkinson's disease. The association between specific cognitive domains and olfactory impairment in Parkinson's disease patients has not been clearly established. This study aimed to evaluate the relationship between olfactory dysfunction and specific cognitive domains in patients compared to controls. The data suggested a significant association between olfactory dysfunction and deficit in executive functions.
Article
Clinical Neurology
Domiziana Rinaldi, Michela Sforza, Francesca Assogna, Cinzia Savini, Marco Salvetti, Carlo Caltagirone, Gianfranco Spalletta, Francesco E. Pontieri
Summary: Safinamide, as a monoamine-oxidase-B inhibitor, has shown positive effects on executive functions in Parkinson's disease patients, improving attention and inhibition of cognitive interference. Add-on treatment with safinamide significantly increases scores on FAB, SWCT, and UPDRS-III, particularly enhancing motor programming and mental flexibility.
JOURNAL OF NEURAL TRANSMISSION
(2021)
Article
Chemistry, Multidisciplinary
Francesca Borgnis, Francesca Baglio, Elisa Pedroli, Federica Rossetto, Mario Meloni, Giuseppe Riva, Pietro Cipresso
Summary: EXIT 360 degrees is an innovative tool for ecologically valid assessment of executive functioning in Parkinson's disease, providing fast, multicomponent, and multidomain evaluations. It can be easily transported for assessments in patient's rooms or houses, significantly improving the convenience and patient engagement in the evaluation process.
APPLIED SCIENCES-BASEL
(2021)
Article
Psychology, Multidisciplinary
Malathi Thothathiri
Summary: The debate over whether sentences are primarily formulated using lexically based or non-lexically based information has been discussed extensively. Evidence suggests that sentences can be constructed flexibly depending on the statistical properties of the input and the validity of lexical vs. abstract cues for predicting sentence structure. Different neural pathways seem to be recruited for individuals with different executive function abilities and for verbs with different statistical properties, indicating alternative routes for producing the same structure. The human brain adapts to ongoing language experience during adulthood, with the nature of the adjustment depending rationally on the statistical contingencies of the current context.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Audiology & Speech-Language Pathology
Emmanouil Anyfantis, Lambros Messinis, Maria Kambanaros, Spyridon Konitsiotis
Summary: This study investigated verb and noun naming abilities in Greek individuals with Parkinson's disease (PD) and explored the effect of semantic complexity on verb retrieval ability. The results showed that PD participants performed worse than healthy controls in naming verbs and nouns, and there was a positive effect of instrumentality on verb retrieval abilities.
Article
Multidisciplinary Sciences
Fabian Klostermann, Moritz Boll, Felicitas Ehlen, Hannes Ole Tiedt, Michelle Wyrobnik
Summary: This study investigated the changes in verb generation ability and semantic relevance in patients with Parkinson's disease (PD) during a language production task. The results showed that PD patients had reduced verb production and lower semantic relevance to body movements. This suggests an impact of motor system states on lexical processing.
SCIENTIFIC REPORTS
(2022)
Review
Neurosciences
Jason K. Longhurst, John Rider, Jeffrey L. Cummings, Samantha E. John, Brach Poston, Merrill R. Landers
Summary: This article investigates the impact of cognitive-motor interference (CMI) on patients with Alzheimer's disease (AD), Parkinson's disease (PD), and prodromal neurodegeneration. A systematic literature search identified 95 articles that reported measures of cognitive-motor dual-task performance in AD, PD, or prodromal neurodegeneration patients. The results show that both AD and PD patients are impacted by CMI, although the impact may differ between the two diseases. Dual-task paradigms have potential in detecting subtle deficits in prodromal AD and PD, but careful consideration should be given to task selection and effect measurement.
Article
Multidisciplinary Sciences
Yunseon Yang, Jae-Jin Song, Yu Ree Choi, Seong-Hoon Kim, Min-Jong Seok, Noviana Wulansari, Wahyu Handoko Wibowo Darsono, Oh-Chan Kwon, Mi-Yoon Chang, Sang Myun Park, Sang-Hun Lee
Summary: Astrocytes have therapeutic potential in alleviating α-synuclein pathology in Parkinson's disease by regulating neuronal α-syn proteostasis and correcting inflammatory environments.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Neurosciences
Andrea M. Loftus, Natalie Gasson, Nicole Lopez, Michelle Sellner, Carly Reid, Naomi Cocks, Blake J. Lawrence
Summary: This study found that different proxies of cognitive reserve have varying effects on executive function and memory in patients with Parkinson's disease, with years of education potentially beneficial for verbal fluency and immediate recall.
Article
Rehabilitation
Wei Wei, Xingyang Yi, Zexiu Wu, Jianghai Ruan, Hua Luo, Xiaodong Duan
Summary: The study found that two weeks of rTMS treatment led to significant improvements in executive function tests and reduced reaction times in the executive control network in Parkinson's disease patients. However, the sham rTMS group did not show any significant changes.
DISABILITY AND REHABILITATION
(2022)
Article
Audiology & Speech-Language Pathology
Eli Hedman, Lena Hartelius, Charlotta Saldert
Summary: This study found that relatively more cognitively demanding controlled oral word association tests (COWATs) can effectively detect word-finding difficulties in persons with Parkinson's disease (PD). Additionally, age and education seem to influence the results of COWAT tasks, while self-perceived word-finding difficulties and motor symptoms are not correlated with the results.
INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS
(2022)
Article
Audiology & Speech-Language Pathology
Roelien Bastiaanse, Martijn Wieling, Nienke Wolthuis
Review
Audiology & Speech-Language Pathology
Anastasia Linnik, Roelien Bastiaanse, Barbara Hoehle
Editorial Material
Audiology & Speech-Language Pathology
Lise Menn, Roelien Bastiaanse
Article
Audiology & Speech-Language Pathology
Bernard A. Jap, Silvia Martinez-Ferreiro, Roelien Bastiaanse
Article
Neurosciences
Stefanie Keulen, Jo Verhoeven, Roelien Bastiaanse, Peter Marien, Roe Jonkers, Nicolas Mavroudakis, Philippe Paquier
FRONTIERS IN HUMAN NEUROSCIENCE
(2016)
Article
Neurosciences
Vania de Aguiar, Roelien Bastiaanse, Gabriele Miceli
FRONTIERS IN HUMAN NEUROSCIENCE
(2016)
Article
Linguistics
S. Martinez-Ferreiro, E. Vares Gonzalez, V. Rosell Clari, R. Bastiaanse
JOURNAL OF NEUROLINGUISTICS
(2017)
Article
Audiology & Speech-Language Pathology
Silvia Martinez-Ferreiro, Andres Felipe Reyes, Roelien Bastiaanse
CLINICAL LINGUISTICS & PHONETICS
(2017)
Article
Audiology & Speech-Language Pathology
Jinxing Yue, Kai Alter, David Howard, Roelien Bastiaanse
LANGUAGE COGNITION AND NEUROSCIENCE
(2017)
Article
Audiology & Speech-Language Pathology
Miren Arantzeta, Roelien Bastiaanse, Frank Burchert, Martijn Wieling, Maite Martinez-Zabaleta, Itziar Laka
LANGUAGE COGNITION AND NEUROSCIENCE
(2017)
Article
Psychology, Clinical
Adria Rofes, Andrea Talacchi, Barbara Santini, Giampietro Pinna, Lyndsey Nickels, Roelien Bastiaanse, Gabriele Miceli
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
(2018)
Article
Linguistics
Srdan Popov, Roelien Bastiaanse
JOURNAL OF NEUROLINGUISTICS
(2018)
Article
Audiology & Speech-Language Pathology
Roelant Ossewaarde, Roel Jonkers, Fedor Jalvingh, Roelien Bastiaanse
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH
(2020)
Review
Neurosciences
Stefanie Keulen, Peter Marien, Kim van Dun, Roelien Bastiaanse, Mario Manto, Jo Verhoeven
Article
Linguistics
Seckin Arslan, Doerte De Kok, Roelien Bastiaanse
BILINGUALISM-LANGUAGE AND COGNITION
(2017)
Article
Behavioral Sciences
Andrea Gajardo-Vidal, Maxime Montembeault, Diego L. Lorca-Puls, Abigail E. Licata, Rian Bogley, Sabrina Erlhoff, Buddhika Ratnasiri, Zoe Ezzes, Giovanni Battistella, Elena Tsoy, Christa Watson Pereira, Jessica Deleon, Boon Lead Tee, Maya L. Henry, Zachary A. Miller, Katherine P. Rankin, Maria Luisa Mandelli, Katherine L. Possin, Maria Luisa Gorno-Tempini
Summary: This study investigates the potential differences in processing speed and neural correlates among the three variants of Primary Progressive Aphasia (PPA). The findings reveal that non-verbal cognitive abilities, such as processing speed, are significantly impacted in nfvPPA and lvPPA patients compared to healthy controls and svPPA patients. Neuroimaging results confirm the importance of fronto-parietal regions associated with processing speed and executive control.
Article
Behavioral Sciences
Holger Wiese, Tsvetomila Popova, Maya Schipper, Deni Zakriev, Mike Burton, Andrew W. Young
Summary: Previous experiments have shown that brief exposure to unfamiliar individuals leads to the formation of new facial representations, which undergo changes and consolidation within the first day after learning.
Article
Behavioral Sciences
Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Paul Wendiggensen, Veit Roessner, Bernhard Hommel, Christian Beste
Summary: Individuals organize events in their environment by partitioning them into discrete units. This study reveals that the neural activity in the brain plays a critical role in this process, reflecting the key elements of event segmentation.
Article
Behavioral Sciences
Zhenzhen Huo, Zhiyi Chen, Rong Zhang, Junye Xu, Tingyong Feng
Summary: Procrastination has adverse effects on personal growth and social development. Reward sensitivity is positively correlated with procrastination. This study used VBM and RSFC analyses to investigate the neural substrates underlying the association between reward sensitivity and procrastination. The results showed that the functional connectivity of the right parahippocampal gyrus-precuneus mediated the relationship between reward sensitivity and procrastination.
Article
Behavioral Sciences
Stefano Lasaponara, Gabriele Scozia, Silvana Lozito, Mario Pinto, David Conversi, Marco Costanzi, Tim Vriens, Massimo Silvetti, Fabrizio Doricchi
Summary: Cholinergic (Ach), Noradrenergic (NE), and Dopaminergic (DA) pathways are crucial in regulating spatial attention and determining inter-individual differences in temperamental traits. This study found that temperamental traits predict individual differences in the ability to orient spatial attention based on the probabilistic association between cues and targets. These findings highlight the importance of considering temperamental and personality traits in social and professional environments where attention control is essential.
Article
Behavioral Sciences
Darren J. Yeo, Courtney Pollack, Benjamin N. Conrad, Gavin R. Price
Summary: The processing of numerals as visual objects is supported by an Inferior Temporal Numeral Area (ITNA) in the bilateral inferior temporal gyri (ITG). Extant findings suggest some degree of hemispheric asymmetry in how the bilateral ITNAs process numerals. The study found that digit sensitivity did not differ between ITNAs, and digit sensitivity in both left and right ITNAs was associated with calculation skills. The study also revealed a right lateralization in engagement in alphanumeric categorization, and that the right ITNA showed greater discriminability between digits and letters.
Review
Behavioral Sciences
Beste Gulsuna, Abuzer Gungor, Alp O. Borcer, Ugur Ture
Summary: The fiber dissection technique has been used to study the internal structures of the brain, with less focus on white matter. The sagittal stratum, a white matter structure, has not received enough attention and has been a subject of controversy. Recent studies suggest potential functions of the sagittal stratum, emphasizing the importance of understanding this structure accurately.
Article
Behavioral Sciences
Nora Geiser, Brigitte Charlotte Kaufmann, Samuel Elia Johannes Knobel, Dario Cazzoli, Tobias Nef, Thomas Nyffeler
Summary: This study compared the effects of auditory and visual motion stimulation on spatial neglect and found that both interventions were equally effective in improving neglect. Multimodal motion stimulation also improved neglect, but did not show greater improvement than unimodal auditory or visual motion stimulation alone.
Article
Behavioral Sciences
Anna E. Hughes, Anna Nowakowska, Alasdair D. F. Clarke
Summary: This study examines the relationship between search slopes and search efficiency in visual search tasks, introduces the Target Contrast Signal (TCS) Theory, and extends it to a Bayesian multi-level framework. The findings demonstrate that TCS can predict data well, but distinguishing between contrast combination models proves to be difficult.