Article
Cardiac & Cardiovascular Systems
Serdar Farhan, Bjoern Redfors, Akiko Maehara, Thomas McAndrew, Ori Ben-Yehuda, Bernard De Bruyne, Roxana Mehran, Birgit Vogel, Gennaro Giustino, Patrick W. Serruys, Gary S. Mintz, Gregg W. Stone
Summary: Insulin resistance is common in patients with acute coronary syndromes. Patients with diabetic-IR or diabetes mellitus have higher rates of adverse plaque characteristics and increased risk of major adverse cardiac events compared to insulin sensitive patients.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Medicine, General & Internal
Brian A. Bergmark, Njambi Mathenge, Piera A. Merlini, Marilyn B. Lawrence-Wright, Robert P. Giugliano
Summary: Although progress has been made in diagnosing and treating acute coronary syndromes, cardiovascular disease remains a leading cause of death globally. High-sensitivity troponin assays have allowed for rapid diagnosis in suspected cases. Dual antiplatelet therapy and additional preventive measures are recommended. The diagnosis and management of acute coronary syndromes continue to evolve, especially in response to the COVID-19 pandemic.
Article
Cardiac & Cardiovascular Systems
Man Wang, Wen Su, Ning Cao, Hui Chen, Hongwei Li
Summary: This study investigated the association between stress hyperglycemia and mortality risk in ACS patients undergoing PCI. The results showed that low and high glucose/GA ratio values were associated with an increased risk of all-cause and cardiovascular mortality.
CARDIOVASCULAR DIABETOLOGY
(2023)
Review
Medicine, General & Internal
Deepak L. Bhatt, Renato D. Lopes, Robert A. Harrington
Summary: This review discusses the current evidence on the epidemiology, pathophysiology, clinical presentation, diagnosis, management, and prognosis of acute coronary syndromes (ACS). ACS is a sudden reduction in blood supply to the heart and includes ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), and unstable angina. Each year, more than 7 million people are diagnosed with ACS worldwide. Prompt intervention, such as primary percutaneous coronary intervention (PCI) for STEMI patients and invasive coronary angiography with revascularization for high-risk NSTE-ACS patients, is associated with reduced mortality.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Review
Cardiac & Cardiovascular Systems
Mingmin Li, Guo Chen, Yingqing Feng, Xuyu He
Summary: SIH is common in ACS patients and associated with adverse outcomes, but its exact definition is controversial; Insulin-based therapy's impact on ACS patient outcomes is inconsistent; The mechanism underlying the detrimental effects of SIH on ACS patients is unclear, with oxidative stress potentially playing a role.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Letter
Medicine, General & Internal
John A. Bittl
Summary: The article discusses the preference for antithrombotic therapy in patients with acute coronary syndromes and the difference between preference and actual practice. It also mentions a new study, but does not explicitly state whether this new study can explain the discrepancy.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Medicine, General & Internal
Leonardo De Luca, Raffaella Mistrulli, Francesco Antonio Veneziano, Francesco Grigioni, Massimo Volpe, Francesco Musumeci, Domenico Gabrielli
Summary: Patients with atrial fibrillation (AF) have an increased risk for coronary artery disease (CAD) after PCI, requiring a delicate balance of antithrombotic therapy to reduce ischemic and bleeding risks. Recent studies show that dual-antithrombotic therapy (DAT) can reduce bleeding events compared to triple-antithrombotic therapy (TAT), and direct-acting oral anticoagulants (DOACs) may have similar benefits over vitamin K antagonist (VKA).
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Ralf E. Harskamp, Alexander C. Fanaroff, Renato D. Lopes, Daniel M. Wojdyla, Shaun G. Goodman, Laine E. Thomas, Ronald Aronson, Stephan Windecker, Roxana Mehran, Christopher B. Granger, John H. Alexander
Summary: Replacing vitamin K antagonists with apixaban and discontinuing aspirin can reduce bleeding and result in comparable ischemic events for patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary intervention.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Claudio Laudani, Antonio Greco, Giovanni Occhipinti, Salvatore Ingala, Dario Calderone, Lorenzo Scalia, Federica Agnello, Marco Legnazzi, Maria Sara Mauro, Carla Rochira, Sergio Buccheri, Roxana Mehran, Stefan James, Dominick J. Angiolillo, Davide Capodanno
Summary: This study compares the effectiveness of short dual antiplatelet therapy (DAPT) and de-escalation in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). The results suggest that de-escalation reduces the risk of adverse cardiovascular events, while short DAPT decreases the occurrence of major bleeding.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Review
Biology
Panagiotis Theofilis, Evangelos Oikonomou, Christos Chasikidis, Konstantinos Tsioufis, Dimitris Tousoulis
Summary: Coronary artery disease and acute coronary syndromes continue to have significant impact on health and life, despite preventive measures and technological advancements. Further exploration of the pathophysiology is necessary to provide tailored and more effective therapies, as the pathogenesis of acute coronary syndrome is more varied than previously assumed, involving plaque rupture, plaque erosion, and calcified nodules. Vascular imaging tools have played a critical role in redefining the epidemiology of each mechanism.
Article
Cardiac & Cardiovascular Systems
Yong Zhu, Kesen Liu, Maolin Chen, Yan Liu, Ang Gao, Chengping Hu, Hong Li, Huagang Zhu, Hongya Han, Jianwei Zhang, Yingxin Zhao
Summary: The triglyceride-glucose (TyG) index is positively associated with in-stent restenosis (ISR) after drug-eluting stent (DES) implantation in patients with acute coronary syndrome (ACS). Higher TyG index is related to higher prevalence of DES-ISR in ACS patients.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Nutrition & Dietetics
Nisar Fatima, Fareeha Anwar, Uzma Saleem, Aslam Khan, Bashir Ahmad, Irum Shahzadi, Hammad Ahmad, Tariq Ismail
Summary: The methanolic extract of Brugmansia aurea has potential antidiabetic activity, increasing insulin sensitivity and reducing insulin resistance in diabetic rats. It also lowers blood glucose levels and improves glucose tolerance.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Medicinal
Masoome Jabarpour, Ashraf Aleyasin, Maryam Shabani Nashtaei, Fardin Amidi
Summary: This study investigated the effect of astaxanthin on infertile polycystic ovarian syndrome (PCOS) patients. The results showed that astaxanthin improved insulin metabolism, lipid profile parameters, and oxidative stress levels in these patients. The study suggests that astaxanthin may be an effective and safe supplement.
PHYTOTHERAPY RESEARCH
(2023)
Article
Endocrinology & Metabolism
Chi Liu, Qi Zhao, Ziwei Zhao, Xiaoteng Ma, Yihua Xia, Yan Sun, Dai Zhang, Xiaoli Liu, Yujie Zhou
Summary: This study found that estimated glucose disposal rate (eGDR) is negatively associated with the risk of in-stent restenosis (ISR) in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) who underwent percutaneous coronary intervention (PCI).
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Medicine, General & Internal
Fatima Rodriguez, Robert A. Harrington
Summary: Antithrombotic therapy is a crucial element in the treatment of acute coronary syndromes, with a focus on antiplatelet therapy. However, balancing the benefits and bleeding risks remains controversial. This review examines clinical research and recommended approaches to management in this area.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Materials Science, Multidisciplinary
Abuzer Acikgoz, Gokhan Demircan, Bulent Aktas, Serife Yalcin, Nuri Yorulmaz, Demet Yilmaz
Summary: The study investigated the impact of CeO2 and Er2O3 on the physical, structural, and mechanical properties of a B2O3-Na2O-Al2O3 glass composition. CeO2 and Er2O3 doping affected radiation shielding properties and optical properties, with 1 mol% Er2O3 showing a better reduction in reflectivity of gamma rays compared to 1 mol% CeO2. The structural and mechanical properties of the doped borate glasses were also examined and compared.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2022)
Article
Materials Science, Composites
Inci Yasaroglu, Omur Aras, Yunus Kaya
Summary: Epoxy resins have great potential for industrial applications due to their excellent properties, but their high viscosity limits their industrial usage. Reducing viscosity with diluents provides an advantage, but may decrease chemical and mechanical properties. It is important to determine additives amount and dilution ratio for specific working area to maintain desirable properties.
POLYMER COMPOSITES
(2022)
Article
Engineering, Civil
Muge Albayrak, Daniel Willi, Sebastien Guillaume
Summary: This study determines the precision and accuracy of the QDaedalus system based on observations at two locations in Switzerland. The precision was found to be 0.1'' through extensive observations, while the accuracy was established through parallel observations and found to be within 0.1''. Notably, a large systematic trend was observed in the N-S DoV data at one of the test stations.
Article
Food Science & Technology
Hamza Alasalvar, Murat Kaya, Serap Berktas, Bulent Basyigit, Mustafa Cam
Summary: This study investigated the extraction of bioactive compounds from lemon peel using pressurised hot water extraction (PHWE). The results showed that PHWE at specific temperature and time conditions could selectively extract eriocitrin and hesperidin, resulting in higher total phenolic content and antioxidant capacities compared to conventional extraction methods.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Civil
Songul Can, Ali Sariisik, Tayfun Uygunoglu
Summary: This study investigates the combined effect of SO4 attack and ultraviolet (UV) radiation on concrete. It is found that materials with high MgO content can increase the workability and durability of concrete.
INNOVATIVE INFRASTRUCTURE SOLUTIONS
(2022)
Article
Engineering, Marine
Gokhan Demircan, Mustafa Ozen, Murat Kisa, Abuzer Acikgoz, Yusuf Isiker
Summary: This study investigated the effects of freeze-thaw test on glass fiber-reinforced epoxy composite coatings with nano-gelcoat. The mechanical properties and thermal stability of the coatings were examined through various tests and analyses. Results showed that the addition of nano TiO2 improved water absorption property and preserved mechanical properties. However, the presence of nanoclay reduced the protection property of the pure gelcoat. Statistical analysis confirmed the significance of the experimental results.
Article
Geography, Physical
Yunus Kaya, Halil Ibrahim Senol, Abdurahman Yasin Yigit, Murat Yakar
Summary: Determining car density in parking lots is crucial for executing existing management systems and making precise plans for the future. In this study, high-resolution UAV images and deep learning methods were used to detect cars in parking lots. Two deep learning approaches, YOLOv3 and Mask R-CNN, were tested using the deep learning tool of Esri ArcGIS Pro. The performance of the algorithms was evaluated based on metrics such as recall, F1 score, precision ratio/uncertainty accuracy, and average producer accuracy.
PHOTOGRAMMETRIC ENGINEERING AND REMOTE SENSING
(2023)
Article
Environmental Sciences
Ibrahim Yenigun, Ali Volkan Bilgili, Halil Ibrahim Senol, Abdullah Yenigun
Summary: Underground water resources are vital for mankind, used for drinking water and agricultural irrigation. This study investigates the changes in groundwater quality in the Upper Mesopotamian region, which has a semi-arid climate and important past civilizations. Samples from selected wells in the Mardin Kiziltepe Plain were collected and analyzed for water quality classifications. The results show no non-standard values and will provide important data for future irrigation projects.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2023)
Article
Environmental Sciences
Inese Varna, Daniel Willi, Sebastien Guillaume, Muge Albayrak, Ansis Zarins, Mustafa Ozen
Summary: Nowadays, zenith telescope-based digital zenith cameras (DZC) are used to determine precise astrogeodetic deflections of the vertical (DoVs). CODIAC and VESTA, developed by ETH Zurich and University of Latvia respectively, are the most commonly used DZCs. This study conducted simultaneous observations using both CODIAC and VESTA at HEIG-VD in Yverdon-les-Bains, Switzerland, and revealed the precision and agreement between the two DZCs.
Article
Archaeology
Nizar Polat
Summary: This study used unmanned aerial vehicles (UAVs) to investigate ancient water collection and storage systems near the Karahantepe Neolithic Site. The use of digital elevation models (DEMs) allowed for the examination of cisterns, pools, and channels in the region. Hydrological analysis provided a comprehensive understanding of water flow patterns. The findings suggested that the channels leading to cisterns followed a meandering slope and culminated in pools, possibly serving as sedimentation ponds. The study highlighted the benefits of utilizing UAV technology in archaeology and inferred that the water collection and storage system in the region was intentionally constructed by ancient civilizations.
ENVIRONMENTAL ARCHAEOLOGY
(2023)
Article
Chemistry, Physical
Mehmet Fatih Dilekoglu, Mazlum Yapici
Summary: The research investigated the performance of a new method for synthesizing super activated carbon from sheep manure in the adsorption of the naproxen micropollutant. Chemical activation with ZnCl2 as an activator was used to produce activated carbon, with various parameters such as impregnation rate, activation temperature, and duration examined. Characterization of the produced activated carbons was done using FTIR, SEM, and BET measurements, with a surface area of 2170 m2 g-1 determined. The adsorption of naproxen was found to be influenced by solution pH, initial concentration, and the amount of activated carbon.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Civil
Muge Albayrak, Sebastien Guillaume, Daniel Willi, Christian Hirt, Ivan Dario Herrera Pinzon, Urs Marti, M. Tevfik Ozludemir, Lukas Mueller, C. K. Shum
Summary: This study presents the results of an astrogeodetic survey campaign conducted in the mountainous terrain of the Surses region in Switzerland. The observations using the QDaedalus system validated DoV data from the CHGeo2004 model and showed that it is more accurate than the GGMplus model. Furthermore, a comparison with previous studies conducted in coastal and flat terrains revealed that the GGMplus model performs better in the mountainous terrain.
JOURNAL OF SURVEYING ENGINEERING
(2023)
Article
Surgery
Harun Gur, Onur Ismi, Yusuf Vayisoglu, Kemal Gorur, Murat Unal, Onurhan Guven, Cengiz Ozcan
Summary: This study retrospectively analyzed the demographic, clinical, surgical, and histopathological results and complications of 301 parotidectomies performed in southern part of Turkey. The study found that patients with malignant tumors had a higher mean age compared to patients with benign diseases. The mean age of Warthin tumor (WT) patients was significantly higher than pleomorphic adenoma (PA) patients. There was a significant male dominancy in WT compared to PA. The mean size of malignant tumors was significantly larger than benign tumors.
INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY
(2023)
Article
Geosciences, Multidisciplinary
Ismail Demiryege, Mustafa Ulukavak
Summary: This study aims to create a deep learning-based model for the prediction of ionospheric TEC. The optimum parameters for forecasting ionospheric TEC variations were investigated using GPS observations from a GNSS station, and a related model was developed.
Article
Geosciences, Multidisciplinary
Halil Ibrahim Senol, Turkay Gokgoz
Summary: This study examined the map drawing and reading skills of primary school students. The results showed that the quality of maps drawn by students did not improve with age and most of them were of medium quality. However, the students demonstrated good abilities in using maps.