Article
Medicine, General & Internal
Punchalee Kaenmuang, Warangkana Keeratichananont, Sarayut Lucien Geater, Nicha Chantamanee, Piyaporn Srikaew
Summary: This study aimed to investigate the prevalence and potential predictors of osteoporosis in COPD patients. The results showed a high prevalence of osteoporosis in COPD patients, with advanced age, lower BMI, history of exacerbation, and high CRP levels being potential predictors. COPD patients without treatment exhibited a rapid decline in bone mineral density.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Eun Mi Yang, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Young Youl Hyun, Suah Sung, Soo Wan Kim
Summary: This study indicates that there is a clear association between low BMD and all-cause mortality in patients with nondialysis CKD. Osteoporosis is significantly associated with an increased risk of all-cause mortality, while osteopenia does not have a significant association. This suggests that the routine measurement of BMD may have additional benefits beyond predicting fracture risk in this population.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pharmacology & Pharmacy
Chia-Hsien Chen, Wei-Cheng Lo, Ping-Jen Hu, Hsiu-Chen Chan, Wan-Chen Shen, Mai-Szu Wu, Mei-Yi Wu
Summary: From network meta-analysis, it was found that teriparatide and denosumab appear to be the most effective treatments for preventing bone loss and reducing the risk of fracture in patients with CKD or a history of kidney transplantation.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Nutrition & Dietetics
Miroslav Vujasinovic, Lorena Nezirevic Dobrijevic, Ebba Asplund, Wiktor Rutkowski, Ana Dugic, Mashroor Kahn, Ingrid Dahlman, Maria Saaf, Hannes Hagstrom, Johannes-Matthias Lohr
Summary: This study found that only 23% of patients with CP underwent DXA examination, with 53.4% of patients having low BMD. The fracture rate was significantly higher in patients with low BMD compared to those with normal BMD.
Review
Respiratory System
Mairi MacLeod, Alberto Papi, Marco Contoli, Bianca Beghe, Bartolome R. Celli, Jadwiga A. Wedzicha, Leonardo M. Fabbri
Summary: Exacerbations in COPD significantly impact disease progression, comorbidities, wellbeing, and mortality. They represent a major socioeconomic burden. Current definitions of exacerbations focus on worsening respiratory symptoms, but other factors can also contribute. Objective measurements like blood counts and C-reactive protein should be used to improve accuracy in diagnosis. Acute management includes interventions like corticosteroids, antibiotics, and non-invasive ventilation. Long-term prevention strategies, such as inhaled therapy and tailored approaches based on clinical phenotypes, are needed to better manage exacerbations.
Article
Endocrinology & Metabolism
Shih-Hao Feng, Ya-Ping Huang, Kuo-Cheng Yeh, Shin-Liang Pan
Summary: The study found that patients with osteoporosis are at increased risk of developing Parkinson's disease, especially among women.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Urology & Nephrology
Hyoungnae Kim, Joongyub Lee, Kyu-Beck Lee, Yeong-Hoon Kim, Namki Hong, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Kyu Hun Choi, Kook-Hwan Oh, Tae-Hyun Yoo
Summary: The study found a significant association between low bone mineral density and the progression of coronary arterial calcification, as well as the risk of major adverse cardiovascular events in patients with predialysis chronic kidney disease.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Surgery
Ya-Chen Chou, Yi-Chia Chan, Shun-Yu Chi, Fong-Fu Chou
Summary: The study showed that despite the greater impact of chronic kidney disease-mineral and bone disorder (CKD-MBD) in the elderly, parathyroidectomy remains an effective intervention for this condition. Elderly patients had similar postoperative bone mineral density and recovery potential as younger patients, with a high success rate and few complications observed.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Medicine, General & Internal
Olivier Malaise, Cecile Andre, Caroline Van Durme, Laurence Seidel, Florence Schleich, Renaud Louis, Michel Malaise, Clio Ribbens
Summary: This study aimed to determine if functional indices associated with emphysema on pulmonary function tests can identify COPD patients with osteoporosis. The results showed that individual functional parameters associated with emphysema were not associated with osteoporosis. However, the combination of functional indices related to hyperinflation and impaired diffusion capacity could significantly predict osteoporosis. Other risk factors for osteoporosis included lower BMI, female gender, and age.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Praneeth Reddy Amudala Puchakayala, Venkata L. Sthanam, Arie Nakhmani, Muhammad F. A. Chaudhary, Abhilash Kizhakke Puliyakote, Joseph M. Reinhardt, Chengcui Zhang, Surya P. Bhatt, Sandeep Bodduluri
Summary: This study evaluated the performance of radiomics features in the diagnosis of COPD and found that a combination of features representing parenchymal texture and lung and airway shape on inspiratory CT scans can accurately detect COPD.
Article
Biochemistry & Molecular Biology
Hussein Sakr, Zenat Khired, Marzieh Moghadas
Summary: This study examined the effect of a wheat grain diet on bone turnover markers in rats. The results showed that rats fed whole or refined grains had lower bone density and mineral content compared to the control group. Additionally, levels of bone turnover indicators in the blood were altered, indicating a decrease in bone turnover and mass with a grain diet.
Article
Nutrition & Dietetics
Nasser M. Al-Daghri, Syed Danish Hussain, Abdullah M. Alnaami, Naji Aljohani, Shaun Sabico
Summary: Osteoporosis is a significant public health concern in Saudi Arabia, particularly among the aging population. This study examined the association between dietary calcium intake and osteoporosis risk in Saudi adults. Results showed that the overall mean calcium intake was very low and that certain dietary factors, such as tea intake and consumption of fish and eggs, were associated with a lower risk of osteoporosis.
Article
Pharmacology & Pharmacy
Xiaofen Huang, Xiaoqiu Wu
Summary: The study on patients with chronic obstructive pulmonary disease revealed that bone mineral density and bone metabolism marker levels can effectively predict secondary osteoporosis in these patients. Through various comparisons and correlations, the study emphasized the significance of bone health in patients with COPD.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Ewa Jowko, Barbara Dlugolecka, Igor Cieslinski, Jadwiga Kotowska
Summary: The aim of this study was to identify relevant factors that affect bone mineral content (BMC) and bone mineral density (BMD) in young, healthy men reaching peak bone mass. The results showed that age, BMI, engaging in combat and team sports at a competitive level, and certain genetic polymorphisms were significant predictors of BMD/BMC at different skeletal sites. Specifically, the SOD2 AG genotype was associated with lower BMC values, while the VDR FokI GG genotype was associated with lower BMD. However, the CALCR AG genotype was linked to higher arm BMD. These findings suggest that sports training may mitigate the negative impact of genetic factors on bone tissue and reduce the risk of osteoporosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Nutrition & Dietetics
Elham Kazemian, Ali Pourali, Fatemeh Sedaghat, Mehrdad Karimi, Vahid Basirat, Zohreh Sajadi Hezaveh, Sayed Hossein Davoodi, Michael F. Holick
Summary: A systematic review and meta-analysis evaluated the effects of vitamin D-3 supplementation on bone health in adults. The results showed a protective effect of vitamin D-3 supplementation on bone mineral density (BMD) at the lumbar spine, femoral neck, and total hip. Dose-response analysis revealed a linear relationship between vitamin D-3 supplementation doses and BMD. However, no significant effect of vitamin D-3 supplementation on whole-body or total hip BMD was found. The relationship between vitamin D-3 supplement doses and markers of bone turnover was nonlinear.
Article
Multidisciplinary Sciences
Kazuya Setoh, Chikashi Terao, Shigeo Muro, Takahisa Kawaguchi, Yasuharu Tabara, Meiko Takahashi, Takeo Nakayama, Shinji Kosugi, Akihiro Sekine, Ryo Yamada, Michiaki Mishima, Fumihiko Matsuda
NATURE COMMUNICATIONS
(2015)
Article
Geriatrics & Gerontology
Kazuya Yoshimura, Susumu Sato, Shigeo Muro, Minoru Yamada, Koichi Hasegawa, Hirofumi Kiyokawa, Michiaki Mishima, Tomoki Aoyama
GERIATRICS & GERONTOLOGY INTERNATIONAL
(2018)
Article
Cardiac & Cardiovascular Systems
Kei Shikuma, Toyofumi F. Chen-Yoshikawa, Tsuyoshi Oguma, Takeshi Kubo, Keiji Ohata, Masatsugu Hamaji, Atsushi Kawaguchi, Hideki Motoyama, Kyoko Hijiya, Akihiro Aoyama, Hisako Matsumoto, Shigeo Muro, Hiroshi Date
ANNALS OF THORACIC SURGERY
(2018)
Article
Multidisciplinary Sciences
Yoshinori Fuseya, Shigeo Muro, Susumu Sato, Naoya Tanabe, Atsuyasu Sato, Kazuya Tanimura, Koichi Hasegawa, Kiyoshi Uemasu, Takeshi Kubo, Aki Kido, Koji Fujimoto, Yasutaka Fushimi, Hiroshi Kusahara, Naotaka Sakashita, Yoshiharu Ohno, Kaori Togashi, Michiaki Mishima, Toyohiro Hirai
Article
Respiratory System
Naoya Tanabe, Shigeo Muro, Susumu Sato, Tsuyoshi Oguma, Atsuyasu Sato, Toyohiro Hirai
BMC PULMONARY MEDICINE
(2018)
Article
Cell & Tissue Engineering
Shimpei Gotoh, Isao Ito, Tadao Nagasaki, Yuki Yamamoto, Satoshi Konishi, Yohei Korogi, Hisako Matsumoto, Shigeo Muro, Toyohiro Hirai, Michinori Funato, Shin-Ichi Mae, Taro Toyoda, Aiko Sato-Otsubo, Seishi Ogawa, Kenji Osafune, Michiaki Mishima
Article
Integrative & Complementary Medicine
Masao Suzuki, Shigeo Muro, Motonari Fukui, Naoto Ishizaki, Susumu Sato, Tetsuhiro Shiota, Kazuo Endo, Tomoko Suzuki, Tadamichi Mitsuma, Michiaki Mishima, Toyohiro Hirai
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2018)
Article
Critical Care Medicine
Jarred R. Mondonedo, Susumu Sato, Tsuyoshi Oguma, Shigeo Muro, Adam H. Sonnenberg, Dean Zeldich, Harikrishnan Parameswaran, Toyohiro Hirai, Bela Suki
Article
Respiratory System
Yoshinori Fuseya, Shigeo Muro, Susumu Sato, Atsuyasu Sato, Kazuya Tanimura, Koichi Hasegawa, Kiyoshi Uemasu, Yoko Hamakawa, Yoshimitsu Takahashi, Takeo Nakayama, Naoki Sakai, Motonari Fukui, Hideo Kita, Tadashi Mio, Michiaki Mishima, Toyohiro Hirai
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2019)
Article
Respiratory System
Shigeo Muro, Hajime Yoshisue, Konstantinos Kostikas, Petter Olsson, Pritam Gupta, Jadwiga A. Wedzicha
Review
Biochemistry & Molecular Biology
Hiroyo Ota, Yukio Fujita, Motoo Yamauchi, Shigeo Muro, Hiroshi Kimura, Shin Takasawa
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Article
Multidisciplinary Sciences
Fumi Mochizuki, Hiroaki Iijima, Azusa Watanabe, Naoya Tanabe, Susumu Sato, Masanari Shiigai, Keiji Fujiwara, Takafumi Shimada, Hiroichi Ishikawa, Jun Kanazawa, Yohei Yatagai, Hironori Masuko, Tohru Sakamoto, Shigeo Muro, Nobuyuki Hizawa
SCIENTIFIC REPORTS
(2019)
Article
Respiratory System
Naoya Tanabe, Tsuyoshi Oguma, Susumu Sato, Takeshi Kubo, Satoshi Kozawa, Hiroshi Shima, Koji Koizumi, Atsuyasu Sato, Shigeo Muro, Kaori Togashi, Toyohiro Hirai
RESPIRATORY INVESTIGATION
(2018)
Article
Respiratory System
Kiminobu Tanizawa, Tomohiro Handa, Takeshi Kubo, Toyofumi F. Chen-Yoshikawa, Akihiro Aoyama, Hideki Motoyama, Kyoko Hijiya, Akihiko Yoshizawa, Yohei Oshima, Kohei Ikezoe, Shinsaku Tokuda, Yoshinari Nakatsuka, Yuko Murase, Sonoko Nagai, Shigeo Muro, Toru Oga, Kazuo Chin, Toyohiro Hirai, Hiroshi Date
RESPIRATORY RESEARCH
(2018)
Article
Respiratory System
Koichi Hasegawa, Susumu Sato, Kazuya Tanimura, Yoshinori Fuseya, Kiyoshi Uemasu, Yoko Hamakawa, Atsuyasu Sato, Michiaki Mishima, Shigeo Muro, Toyohiro Hirai
RESPIRATORY INVESTIGATION
(2018)