Organization of junctional sarcoplasmic reticulum proteins in skeletal muscle fibers

Deletion of small ankyrin 1 (sAnk1) isoforms results in structural and functional alterations in aging skeletal muscle fibers

(2015) E. Giacomello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of Mitofusin-2 in mitochondrial localization and calcium uptake in skeletal muscle

(2015) Alina Ainbinder et al.   CELL CALCIUM

Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation

(2015) Bo Van et al.   FEBS LETTERS

A new cytoplasmic interaction between junctin and ryanodine receptor Ca2+ release channels

(2015) L. Li et al.   JOURNAL OF CELL SCIENCE

Functional implications of mitofusin 2-mediated mitochondrial-SR tethering

(2015) Gerald W. Dorn et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Retrograde regulation of STIM1-Orai1 interaction and store-operated Ca2+ entry by calsequestrin

(2015) Limin Wang et al.   Scientific Reports

The molecular architecture of dihydropyrindine receptor/L-type Ca2+ channel complex

(2015) Hongli Hu et al.   Scientific Reports

The Mitochondrial Calcium Uniporter Controls Skeletal Muscle Trophism In Vivo

(2015) Cristina Mammucari et al.   Cell Reports

C-terminal residues of skeletal muscle calsequestrin are essential for calcium binding and for skeletal ryanodine receptor inhibition

(2015) Nicole A Beard et al.   Skeletal Muscle

At the right distance: ER-mitochondria juxtaposition in cell life and death

(2014) Deborah Naon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Microtubule-Mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte Transverse-Tubule Remodeling and Ca 2+ Handling Dysfunction in Heart Failure

(2014) Caimei Zhang et al.   CIRCULATION

Nonuniform and Variable Arrangements of Ryanodine Receptors Within Mammalian Ventricular Couplons

(2014) Parisa Asghari et al.   CIRCULATION RESEARCH

N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy

(2014) S. Falcone et al.   EMBO Molecular Medicine

A Mutation in theCASQ1Gene Causes a Vacuolar Myopathy with Accumulation of Sarcoplasmic Reticulum Protein Aggregates

(2014) Daniela Rossi et al.   HUMAN MUTATION

Structure of a mammalian ryanodine receptor

(2014) Ran Zalk et al.   NATURE

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

(2014) Zhen Yan et al.   NATURE

Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca2+channels

(2014) Alexander Polster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BIN1/M-Amphiphysin2 induces clustering of phosphoinositides to recruit its downstream partner dynamin

(2014) Laura Picas et al.   Nature Communications

The “Goldilocks Zone” from a redox perspective—Adaptive vs. deleterious responses to oxidative stress in striated muscle

(2014) Rick J. Alleman et al.   Frontiers in Physiology

Targeted ablation of the histidine-rich Ca2+-binding protein (HRC) gene is associated with abnormal SR Ca2+-cycling and severe pathology under pressure-overload stress

(2013) Chang Sik Park et al.   BASIC RESEARCH IN CARDIOLOGY

Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P3and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response

(2013) Hayley J. Bennett et al.   BIOCHEMICAL JOURNAL

Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum

(2013) Daniela Rossi et al.   BIOCHEMICAL JOURNAL

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The myotubularin–amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

(2013) Barbara Royer et al.   EMBO REPORTS

Skeletal muscle excitation–contraction coupling: Who are the dancing partners?

(2013) Robyn T. Rebbeck et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Novel Details of Calsequestrin Gel Conformationin Situ

(2013) Stefano Perni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion Pathways in the Sarcoplasmic Reticulum Ca2+-ATPase

(2013) Maike Bublitz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity

(2013) Davide Randazzo et al.   JOURNAL OF CELL BIOLOGY

Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo

(2013) L. Amoasii et al.   JOURNAL OF CELL SCIENCE

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling

(2013) V. Eisner et al.   JOURNAL OF CELL SCIENCE

Mutation E169K in Junctophilin-2 Causes Atrial Fibrillation Due to Impaired RyR2 Stabilization

(2013) David L. Beavers et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling

(2013) Clare V Logan et al.   NATURE GENETICS

Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility

(2013) B. R. Nelson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stac3 is a component of the excitation–contraction coupling machinery and mutated in Native American myopathy

(2013) Eric J. Horstick et al.   Nature Communications

Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+transfer from the sarcoplasmic reticulum to the mitochondria in the heart

(2012) Choon Kee Min et al.   BIOCHEMICAL JOURNAL

Catecholaminergic Polymorphic Ventricular Tachycardia

(2012) Antoine Leenhardt et al.   Circulation-Arrhythmia and Electrophysiology

Endogenously determined restriction of food intake overcomes excitation–contraction uncoupling in JP45KO mice with aging

(2012) Osvaldo Delbono et al.   EXPERIMENTAL GERONTOLOGY

Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human

(2012) Nathalie Roux-Buisson et al.   HUMAN MOLECULAR GENETICS

JP-45/JSRP1Variants Affect Skeletal Muscle Excitation-Contraction Coupling by Decreasing the Sensitivity of the Dihydropyridine Receptor

(2012) Toshimichi Yasuda et al.   HUMAN MUTATION

Hypertrophy in Skeletal Myotubes Induced by Junctophilin-2 Mutant, Y141H, Involves an Increase in Store-operated Ca2+Entry via Orai1

(2012) Jin Seok Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Molecular Architecture of Human Caveolin-3 and Interaction with the Skeletal Muscle Ryanodine Receptor

(2012) Gareth Whiteley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle

(2012) R. M. Murphy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover

(2012) Stephan Lange et al.   MOLECULAR BIOLOGY OF THE CELL

Triadin/Junctin Double Null Mouse Reveals a Differential Role for Triadin and Junctin in Anchoring CASQ to the jSR and Regulating Ca2+ Homeostasis

(2012) Simona Boncompagni et al.   PLoS One

A Skeletal Muscle Ryanodine Receptor Interaction Domain in Triadin

(2012) Elize Wium et al.   PLoS One

Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points

(2011) Cecília García-Pérez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression

(2011) Peidong Han et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sarcalumenin plays a critical role in age-related cardiac dysfunction due to decreases in SERCA2a expression and activity

(2011) Qibin Jiao et al.   CELL CALCIUM

Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors After Acute Junctophilin Knockdown in Mice

(2011) Ralph J. van Oort et al.   CIRCULATION

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling

(2011) Andrew P. Landstrom et al.   Circulation-Heart Failure

Role of Junctin Protein Interactions in Cellular Dynamics of Calsequestrin Polymer upon Calcium Perturbation

(2011) Keun Woo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Junctophilin 1 and 2 Proteins Interact with the L-type Ca2+Channel Dihydropyridine Receptors (DHPRs) in Skeletal Muscle

(2011) Lucia Golini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic γ-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers

(2011) David S. Gokhin et al.   JOURNAL OF CELL BIOLOGY

Integrity of the network sarcoplasmic reticulum in skeletal muscle requires small ankyrin 1

(2011) M. A. Ackermann et al.   JOURNAL OF CELL SCIENCE

Electrostatic Interactions Mediate Binding of Obscurin to Small Ankyrin 1: Biochemical and Molecular Modeling Studies

(2011) Ben Busby et al.   JOURNAL OF MOLECULAR BIOLOGY

Voltage-Gated Calcium Channels

(2011) W. A. Catterall   Cold Spring Harbor Perspectives in Biology

Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies

(2010) Anne Toussaint et al.   ACTA NEUROPATHOLOGICA

The sarcomeric cytoskeleton: who picks up the strain?

(2010) Mathias Gautel   CURRENT OPINION IN CELL BIOLOGY

Impaired Orai1-mediated Resting Ca2+Entry Reduces the Cytosolic [Ca2+] and Sarcoplasmic Reticulum Ca2+Loading in Quiescent Junctophilin 1 Knock-out Myotubes

(2010) Hongli Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The β Subunit of Voltage-Gated Ca2+ Channels

(2010) Zafir Buraei et al.   PHYSIOLOGICAL REVIEWS

Ca2+ transfer from the ER to mitochondria: When, how and why

(2009) Rosario Rizzuto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin

(2009) Lan Wei et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum

(2009) S. Lange et al.   JOURNAL OF CELL SCIENCE

Excitation–contraction coupling changes during postnatal cardiac development

(2009) Andrew P. Ziman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calsequestrin-1: a new candidate gene for malignant hyperthermia and exertional/environmental heat stroke

(2009) Feliciano Protasi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Minor sarcoplasmic reticulum membrane components that modulate excitation-contraction coupling in striated muscles

(2009) Susan Treves et al.   JOURNAL OF PHYSIOLOGY-LONDON

Triadin: what possible function 20 years later?

(2009) Isabelle Marty et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glutamate at position 227 of junctophilin-2 is involved in binding to TRPC3

(2009) Jin Seok Woo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Assembly and dynamics of proteins of the longitudinal and junctional sarcoplasmic reticulum in skeletal muscle cells

(2009) V. Cusimano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered stored calcium release in skeletal myotubes deficient of triadin and junctin

(2008) Ying Wang et al.   CELL CALCIUM

Localization of ank1.5 in the sarcoplasmic reticulum precedes that of SERCA and RyR: relationship with the organization of obscurin in developing sarcomeres

(2008) Emiliana Giacomello et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Calsequestrin content and SERCA determine normal and maximal Ca2+storage levels in sarcoplasmic reticulum of fast- and slow-twitch fibres of rat

(2008) Robyn M. Murphy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle

(2008) Nicole Vlahovich et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondria Are Linked to Calcium Stores in Striated Muscle by Developmentally Regulated Tethering Structures

(2008) Simona Boncompagni et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

The Sarcoplasmic Reticulum: An Organized Patchwork of Specialized Domains

(2008) Daniela Rossi et al.   TRAFFIC

Immuno-proteomic approach to excitation–contraction coupling in skeletal and cardiac muscle: Molecular insights revealed by the mitsugumins

(2007) Noah Weisleder et al.   CELL CALCIUM