Article
Allergy
Anne Birgitte Simonsen, Jojo Biel-Nielsen Dietz, Jeanne Duus Johansen
Summary: This study aimed to explore the epidemiology, aetiology and severity of hand eczema (HE) among Danish adolescents. The study found a high prevalence of HE among Danish adolescents, raising concerns about this significant clinical problem.
CONTACT DERMATITIS
(2023)
Review
Biochemistry & Molecular Biology
Yu Sawada
Summary: The skin, as the outermost layer of the human body, is constantly exposed to external stimuli, which can lead to skin irritation. Occupational skin diseases, especially in the healthcare sector, are the most common work-related illnesses. During the COVID-19 pandemic, healthcare professionals experienced a range of occupational skin diseases associated with their work. This review focuses on the characteristics of these skin disorders in COVID-19-engaged healthcare professionals and explores potential pathogenesis and preventive methods.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Dermatology
F. Larese Filon, M. Pesce, M. S. Paulo, T. Loney, A. Modenese, S. M. John, S. Kezic, J. Macan
Summary: Healthcare workers are at increased risk of developing occupational contact dermatitis (OCD) due to frequent hand washing and glove use. Incidence rates of OCD vary among different regions and time periods, with higher rates observed in specific occupational groups like dental practitioners. Prospective cohort studies are needed to accurately estimate OCD incidence and develop prevention strategies, especially during pandemics.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Review
Medicine, General & Internal
Cara Symanzik, Yasemin Topal Yueksel, Maria Oberlander Christensen, Jacob P. Thyssen, Christoph Skudlik, Swen Malte John, Richard Brans, Tove Agner
Summary: This study aims to compile and evaluate evidence regarding the prevalence and incidence of occupational hand eczema (HE) in healthcare workers (HCWs). By conducting systematic searches and analysis of published studies, the study will provide insights into the situation and severity of HE among HCWs.
Article
Allergy
Cara Symanzik, Lukasz Stasielowicz, Richard Brans, Christoph Skudlik, Swen Malte John
Summary: An intervention for occupational hand eczema prevention in healthcare workers during the COVID-19 pandemic was found to be effective in reducing disease occurrence and improving skin care behavior.
CONTACT DERMATITIS
(2022)
Article
Dermatology
M. Havmose, J. P. Thyssen, C. Zachariae, J. D. Johansen
Summary: The cumulative lifetime prevalence of occupational hand eczema increased in hairdressers, but the incidence rate decreased. Key risk factors for developing hand eczema among hairdressers included a previous positive patch test, a history of atopic dermatitis, and female sex.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Allergy
Anne B. Simonsen, Iben F. Ruge, Anna S. Quaade, Jeanne D. Johansen, Jacob P. Thyssen, Claus Zachariae
Summary: After implementing more intensive hand hygiene measures in Danish daycare centers, a high proportion of young children rapidly developed hand eczema. Prophylactic skin care could have potentially prevented some children from developing hand eczema.
CONTACT DERMATITIS
(2021)
Article
Dermatology
Nils Hamnerius, Ann Ponten, Ola Bergendorff, Magnus Bruze, Jonas Bjork, Cecilia Svedman
Summary: The COVID-19 pandemic has brought attention to occupational skin diseases in healthcare workers, especially in relation to hygiene procedures and personal protective equipment. Caring for COVID-19 patients involved higher levels of wet work and face mask exposures, leading to increased prevalence of hand eczema and facial skin disease. A dose-dependent association was found between face mask use and acne and eczema, as well as between hand eczema and exposure to soap and gloves.
ACTA DERMATO-VENEREOLOGICA
(2021)
Article
Allergy
Andreas Brynolf, Inese Hauksson, Ola Bergendorff, Cecilia Svedman, Nils Hamnerius
Summary: During the COVID-19 pandemic, the use of face masks by healthcare workers has led to an increase in adverse skin reactions. However, no contact allergies to the tested face masks were found in this study. Eczema was the most common type of skin reaction observed.
CONTACT DERMATITIS
(2023)
Article
Public, Environmental & Occupational Health
C. Symanzik, C. Skudlik, S. M. John
Summary: This study aimed to assess important parameters for the acceptance of a skincare concept in healthcare workers. The results showed that acceptance is influenced by parameters such as self-assessed skin tolerance and self-reported overall satisfaction.
OCCUPATIONAL MEDICINE-OXFORD
(2023)
Review
Allergy
Enver De Wei Loh, Yik Weng Yew
Summary: Hand eczema is significantly associated with frequent handwashing, with washing hands at least 8-10 times daily increasing the risk. However, the use of alcohol-based hand sanitizer is not significantly related to hand eczema risk. Therefore, it is important to emphasize proper hand care practices when implementing hand hygiene measures.
CONTACT DERMATITIS
(2022)
Article
Public, Environmental & Occupational Health
Alicia S. T. Loi, Zeenathnisa M. Aribou, Yuke Tien Fong
Summary: This study aims to identify and implement suitable workplace interventions to aid in the recovery of occupational irritant hand dermatitis among healthcare workers during the COVID-19 pandemic. The results showed that workplace interventions such as substituting irritant hand hygiene products with gentler alternatives and temporary reduction in clinical duties may be useful in improving the recovery rate of irritant hand dermatitis among healthcare professionals.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Dermatology
Advika Dani, Amarachi Eseonu, Kristin Bibee
Summary: The COVID-19 pandemic has led to the development of maskne among healthcare workers, with gender and duration of mask use identified as significant risk factors. The findings suggest the need for targeted prevention education.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
Jonathan Silverberg, Erin M. Warshaw, Amber R. Atwater, Howard Maibach, Kathryn A. Zug, Margo J. Reeder, Denis Sasseville, James S. Taylor, Joseph F. Fowler, Melanie D. Pratt, Anthony F. Fransway, Matthew J. Zirwas, Donald Belsito, James G. Marks, Vincent A. DeLeo, Joel G. DeKoven
Summary: This study retrospectively analyzed data from a large number of patients with hand eczema (HE), and found that HE was associated with higher proportions of positive patch tests, with a heterogeneous profile of allergens.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Allergy
Jacob P. Thyssen, Marie L. A. Schuttelaar, Jose H. Alfonso, Klaus E. Andersen, Irena Angelova-Fischer, Bernd W. M. Arents, Andrea Bauer, Richard Brans, Alicia Cannavo, Wianda A. Christoffers, Marie-Noelle Crepy, Peter Elsner, Manige Fartasch, Francesca Larese Filon, Ana M. Gimenez-Arnau, Margarida Goncalo, Maria G. Guzman-Perera, Carsten R. Hamann, Wolfram Hoetzenecker, Jeanne Duus Johansen, Swen M. John, Amalia C. M. Kunkeler, Suzana Ljubojevic Hadzavdic, Sonja Molin, Rosemary Nixon, Jart A. F. Oosterhaven, Thomas Rustemeyer, Esther Serra-Baldrich, Mili Shah, Dagmar Simon, Christoph Skudlik, Radoslaw Spiewak, Skaidra Valiukeviciene, Angelique N. Voorberg, Elke Weisshaar, Tove Agner
Summary: Hand eczema is a common inflammatory skin disorder. This article aims to update the European Society of Contact Dermatitis guideline on the diagnosis, prevention, and treatment of hand eczema. Consensus was reached for several statements and management strategies through analysis of evidence for therapeutic and preventive interventions using a structured method of developing consensus. The updated guideline should improve the management of hand eczema.
CONTACT DERMATITIS
(2022)
Letter
Dermatology
Mattias Henning, Kristina Ibler, Isabella Loft, Poul Jennum, Maria Didriksen, Henrik Ullum, Christian Erikstrup, Kaspar Nielsen, Mie Topholm Bruun, Henrik Hjalgrim, Erik Sorensen, Khoa Dinh, Lise Wegner Thorner, Gregor B. Jemec, Ole Pedersen
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Review
Dermatology
Farnam Barati Sedeh, Thorunn Elisabet Michaelsdottir, Mattias Arvid Simon Henning, Gregor Borut Ernst Jemec, Kristina Sophie Ibler
Summary: The aim of this study was to compare the efficacy and safety of Janus kinase inhibitors for alopecia areata, using change in Severity of Alopecia Tool (SALT) score as the measure. A systematic review following PRISMA guidelines was conducted, including all studies investigating the efficacy of treatments for alopecia areata. A meta-analysis of randomized controlled trials was performed, and the findings suggest that baricitinib and deuruxolitinib show promising results for the treatment of alopecia areata, with response varying based on dosage.
ACTA DERMATO-VENEREOLOGICA
(2023)
Editorial Material
Dermatology
Sofia H. C. Botvid, Lone Storgaard Hove, Dorra Bouazzi, Rune Kjaersgaard Andersen, Simon Francis Thomsen, Ditte Marie Saunte, Gregor B. E. Jemec
ACTA DERMATO-VENEREOLOGICA
(2023)
Letter
Immunology
Tanja Roehmer Wriedt, Kristoffer Nagy Skaastrup, Pernille Lindsoe Andersen, Line Simmelsgaard, Gregor B. E. Jemec, Ditte M. L. Saunte
Article
Allergy
Farnam Barati Sedeh, Thorunn Elisabet Michaelsdottir, Gregor Borut Ernst Jemec, Ole Steen Mortensen, Kristina Sophie Ibler
Summary: This study examined the level of knowledge regarding skin protective behavior and risk factors for hand eczema among hospital cleaners in Denmark. The results showed that the cleaners had a low level of knowledge, with only about 5 out of 9 questions answered correctly on average. The study also found that cleaners born or raised outside of Denmark had a lower level of knowledge.
CONTACT DERMATITIS
(2023)
Article
Dermatology
K. R. van Straalen, T. Tzellos, A. Alavi, F. Benhadou, C. Cuenca-Barrales, M. Daxhelet, M. Daoud, O. Efthymiou, E. J. Giamarellos-Bourboulis, P. Guillem, W. Gulliver, G. B. E. Jemec, A. C. Katoulis, A. Koenig, E. Lazaridou, M. A. Lowes, A. Marzano, L. Matusiak, A. Molina-Leyva, C. Moltrasio, A. Pinter, C. Potenza, E. P. Prens, J. Romani, D. M. Saunte, C. J. Sayed, N. Skroza, D. Stergianou, J. C. Szepietowski, A. Trigoni, E. Vilarrasa, A. Kyrgidis, C. C. Zouboulis, H. H. van der Zee
Summary: This study validates the novel IHS4-55 outcome measure by showing its significant association with reduction in inflammatory lesion counts and achievement of MCIDs for DLQI, NRS Pain, and NRS Pruritus in an antibiotic-treated cohort. These findings support the use of IHS4-55 as a novel primary outcome measure in clinical trials.
Letter
Dermatology
Amit Garg, Sahil Rawal, Oleg Akilov, Afsaneh Alavi, Christine Ardon, Falk G. Bechara, Arnon D. Cohen, Steven R. Cohen, Steven Daveluy, Veronique del Marmol, Maia Delage, Solveig Esmann, Shani Fisher, Evangelos J. Giamarellos-Bourboulis, Amelia Glowaczewska, Noah Goldfarb, Elena Gonzalez Brant, Oystein Grimstad, Sandra Guilbault, Iltefat Hamzavi, Rosalind Hughes, John R. Ingram, Gregor B. E. Jemec, Qiang Ju, Naomi Kappe, Brian Kirby, Joslyn S. Kirby, Michelle A. Lowes, Lukasz Matusiak, Stella Micha, Robert G. Micheletti, Angela P. Miller, Dagfinn Moseng, Haley B. Naik, Aude Nassif, Georgios Nikolakis, So Yeon Paek, Jose Carlos Pascual, Errol Prens, Barry Resnik, Hassan Riad, Christopher Sayed, Saxon D. Smith, Yssra Soliman, Jacek C. Szepietowski, Jerry Tan, Linnea Thorlacius, Thrasyvoulos Tzellos, Hessel H. van der Zee, Bente Villumsen, Lanqi Wang, Christos C. Zouboulis, Andrew Strunk
Summary: Patients with hidradenitis suppurativa are greatly affected in their lives. Factors such as younger age, Black race, high BMI, active smoking, flares, depression, anxiety, high comorbidity burden, disability, and difficult access to a dermatologist have a negative impact on their quality of life. Attention should be given to these factors, especially those that can be modified, to reduce the overall impact of the disease.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Review
Dermatology
Rami Nabil Al-Chaer, Dorra Bouazzi, Gregor Jemec, Mette Mogensen
Summary: Optical coherence tomography (OCT) and reflectance confocal microscopy (RCM) can provide high-resolution diagnosis and treatment evaluation for common skin disorders such as acne vulgaris, rosacea, and folliculitis. These imaging techniques have the ability to assess the characteristics and quantitative features of hair follicles in various skin disorders, supporting clinical diagnosis and treatment evaluation. However, larger and better-designed studies are needed to implement RCM and OCT in clinical practice.
EXPERIMENTAL DERMATOLOGY
(2023)
Article
Dermatology
K. B. E. Holm, L. J. Nielsen, J. Lock-Andersen, N. Behrendt, M. S. Svensson, L. Themstrup, G. B. E. Jemec
Summary: This study compared the effectiveness of clinical examination, histopathology, and optical coherence tomography (OCT) in delineating the tumor margins of facial basal cell carcinomas (BCC) before surgery. The results showed that OCT and histopathology were in agreement in 86.6% of the data points collected. The study supports the use of OCT in clinical practice for aiding clinicians in preoperative delineation of BCC lesions.
JOURNAL OF CUTANEOUS PATHOLOGY
(2023)
Article
Dermatology
Ehiaghe Lonia Anaba, Dorra Bouazzi, Pelumi Victor Ajayi, Oluwapelumi Olumide Aro, Jurr Boer, Gregor Jemec
Summary: This study aimed to uncover the prevalence of Hidradenitis Suppurativa (HS) in Lagos, Nigeria, validate an HS screening questionnaire, and contribute to the Global Hidradenitis Suppurativa Atlas (GHiSA). The study found a prevalence of 2.2% for HS in the sample, with no gender predominance. BMI did not appear to be a risk factor, and the axilla was the most affected site. All patients had mild disease severity (Hurley Score I).
Article
Pharmacology & Pharmacy
A. S. Byrd, A. Z. Rosenberg, W. D. Shipman, U. J. Okoh, M. Mazhar, G. A. Okoye, N. L. Bragazzi, C. Mortellaro, G. B. E. Jemec, G. Damiani
Summary: A study investigated the prevalence and morbidity of hidradenitis suppurativa (HS) in Black and White patients. The research found that although there were no significant differences in clinical presentation, Black patients had more severe diseases. It is speculated that these ethnic differences may be related to social factors.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Dermatology
Pernille Lindso Andersen, Bente Villumsen, Ditte Marie Lindhardt Saunte, Kristoffer Solvsten Burgdorf, Maria Didriksen, Sisse Rye Ostrowski, Lise Wegner Thorner, Christian Erikstrup, Khoa Manh Dinh, Kaspar Rene Nielsen, Thorsten Brodersen, Mie Topholm Bruun, Karina Banasik, Thomas Folkmann Hansen, Ole Birger Pedersen, Gregor Borut Jemec
Summary: This study explores the possible association between HS and ADHD, and finds a positive correlation between ADHD and HS. This result has significant implications for the research on psychiatric comorbidity of HS.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
Pernille Lindso Andersen, Gregor Borut Ernst Jemec, Christian Erikstrup, Maria Didriksen, Khoa Manh Dinh, Susan Mikkelsen, Mie Topholm Bruun, Henrik Hjalgrim, Thomas Folkmann Hansen, Susanne Gjorup Saekmose, Sisse Rye Ostrowski, Ole Birger Pedersen, Ditte Marie Saunte
Summary: This study found two protective HLA alleles, DQB1*06:04 and DRB1*13:02, that can reduce the risk of onychomycosis.
SKIN APPENDAGE DISORDERS
(2023)
Review
Dermatology
Terri Shih, Sarah Park, Linnea R. Thorlacius, Steven Daveluy, Amit Garg, Susanne D. Goegji, Joslyn S. Kirby, Barry M. McGrath, Peter T. Riis, Bente Villumsen, Kari Zalik, Gregor B. E. Jemec, Jennifer L. L. Hsiao
Summary: Drainage from chronic wounds can greatly affect a patient's quality of life, and measuring the change in wound drainage is important for assessing treatment effectiveness. This study reviews existing tools for evaluating wound drainage, highlighting the limitations and gaps in the current measurement landscape. Development of a concise drainage measurement tool for inflammatory skin diseases with prominent drainage symptoms will enhance treatment monitoring.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
P. Lindso Andersen, G. B. Jemec, C. Erikstrup, M. Didriksen, K. M. Dinh, S. Mikkelsen, E. Sorensen, K. R. Nielsen, M. T. Bruun, H. Hjalgrim, T. F. Hansen, S. G. Saekmose, S. R. Ostrowski, D. M. L. Saunte, O. B. Pedersen
Summary: This study investigated the association between HLA alleles and MRSD, identifying five novel associations and confirming one previous association.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)