ROCK inhibition enhances aggrecan deposition and suppresses matrix metalloproteinase-3 production in human articular chondrocytes

Tensile strain increases expression of CCN2 and COL2A1 by activating TGF-β-Smad2/3 pathway in chondrocytic cells

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ROCK inhibitor prevents the dedifferentiation of human articular chondrocytes

(2012) Emi Matsumoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comparison between normal and loose fragment chondrocytes in proliferation and redifferentiation potential

(2012) Kenichiro Sakata et al.   INTERNATIONAL ORTHOPAEDICS

Chondromodulin-I derived from the inner meniscus prevents endothelial cell proliferation

(2012) Masataka Fujii et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mechanical stretch increases CCN2/CTGF expression in anterior cruciate ligament-derived cells

(2011) Yoshiaki Miyake et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inner Meniscus Cells Maintain Higher Chondrogenic Phenotype Compared with Outer Meniscus Cells

(2011) Takayuki Furumatsu et al.   CONNECTIVE TISSUE RESEARCH

Mechanical stretch enhances COL2A1 expression on chromatin by inducing SOX9 nuclear translocalization in inner meniscus cells

(2011) Tomoko Kanazawa et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Comparison between loose fragment chondrocytes and condyle fibrochondrocytes in cellular proliferation and redifferentiation

(2011) Naoki Takata et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Alleviating Effects of AS1892802, a Rho Kinase Inhibitor, on Osteoarthritic Disorders in Rodents

(2011) Nobuaki Takeshita et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Osteoarthritis year 2010 in review: pathomechanisms

(2011) W.B. van den Berg   OSTEOARTHRITIS AND CARTILAGE

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(2010) Hui B. Sun   Annals of the New York Academy of Sciences

Combined use of bFGF and GDF-5 enhances the healing of medial collateral ligament injury

(2010) Kenta Saiga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of the cartilage matrix in osteoarthritis

(2010) Dick Heinegård et al.   Nature Reviews Rheumatology

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

(2010) Takayuki Shiomi et al.   PATHOLOGY INTERNATIONAL

Rho kinase–dependent activation of SOX9 in chondrocytes

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Anterior cruciate ligament-derived cells have high chondrogenic potential

(2009) Takayuki Furumatsu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Scleraxis and E47 cooperatively regulate the Sox9-dependent transcription

(2009) Takayuki Furumatsu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mechanical stretch stimulates integrin αVβ3-mediated collagen expression in human anterior cruciate ligament cells

(2009) Tomonori Tetsunaga et al.   JOURNAL OF BIOMECHANICS

Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation

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The Transcriptional Activity of Sox9 in Chondrocytes Is Regulated by RhoA Signaling and Actin Polymerization

(2009) D. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

Smad3 activates the Sox9-dependent transcription on chromatin

(2008) Takayuki Furumatsu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Gene expression profiles of human chondrocytes during passaged monolayer cultivation

(2008) Zhen Lin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

L-Sox5 and Sox6 Drive Expression of the Aggrecan Gene in Cartilage by Securing Binding of Sox9 to a Far-Upstream Enhancer

(2008) Y. Han et al.   MOLECULAR AND CELLULAR BIOLOGY

ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes

(2007) Haibing Peng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

In vitro expansion affects the response of chondrocytes to mechanical stimulation

(2007) R.H.J. Das et al.   OSTEOARTHRITIS AND CARTILAGE