Improvement of microcalcification cluster detection in mammography utilizing image enhancement techniques

In this work. the effect of an image enhancement processing stage and the parameter tuning of a computer-aided detection (CAD) system for the detection of microcalcifications in mammograms is assessed. Five (5) image enhancement algorithms were tested introducing the contrast-limited adaptive histogram equalization (CLAHE), the local range modification (LRM) and the redundant discrete wavelet (RDW) linear stretching and shrinkage algorithms. CAD tuning optimization was targeted to the percentage of the most contrasted pixels and the size of the minimum detectable object which could satisfactorily represent a microcalcification. The highest performance in two mammographic datasets, were achieved for LRM (A(Z) = 0.932) and the wavelet-based linear stretching (AZ = 0.926) methodology. (C) 2008 Elsevier Ltd. All rights reserved.