Journal
COMPUTERS IN BIOLOGY AND MEDICINE
Volume 38, Issue 3, Pages 304-312Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compbiomed.2007.10.009
Keywords
rheological model; PMMA; image guided surgery; virtual reality; medical simulation; hand-eye coordination; tactile and visual interfaces; biomechanical modeling
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We have developed a computationally efficient rheological model to simulate polymethylmethacrylate (PMMA) injection into cancellous bone during percutaneous vertebroplasty. The model employs the Hagen-Poiseuille law to predict pressure drop across a delivery cannula with viscoelastic changes of curing PMMA modeled via a time and shear-rate-dependant power law. The power law was derived based on dynamic rheological testing of curing PMMA samples. In conjunction with a branching-pipe geometrical model that is reconstructed from micro-computed tomography scans of cancellous bone for estimating pressure changes during PMMA flow in bone, the method provides a fast estimation of overall injection pressure, and, hence, the reaction force during manual PMMA injection. (C) 2007 Elsevier Ltd. All rights reserved.
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