Article
Oncology
Celine Lechartier, Juliette Bernard, Marie-Claude Renaud, Marie Plante
Summary: This study retrospectively evaluated the outcome of robotic-assisted surgery for endometrial cancer in obese patients with a BMI >= 40 kg/m2. The study found that complications and outcomes were similar in both groups of patients.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Yunhe Gao, Hongqing Xi, Fredrik Mattsson, Wenquan Liang, Shao-Hua Xie, Lin Chen, Jesper Lagergren
Summary: Previous studies have shown that the surgical starting time of the day may affect the long-term survival of gastric cancer patients. This cohort study included 2728 patients who underwent curatively intended gastrectomy for gastric cancer in China. The results indicated that starting surgery in the early morning might be associated with better long-term survival, especially for patients who underwent laparoscopic gastrectomy and those with stage II tumors.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Sanaa Nakad Borrego, Katherine Kurnit, Laura Jane Turner, Russell R. Broaddus
Summary: This study aimed to investigate the association between aging or body mass index and MLH1 methylation in sporadic endometrial cancer. The results showed that age and body mass index were associated with MLH1 methylation in different grades of endometrial cancer.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2023)
Article
Oncology
Ashley S. Felix, Toluwaniose Nafiu, Casey M. Cosgrove, Aldenise P. Ewing, Christian Mpody
Summary: Racial/ethnic disparities exist in surgical outcomes of hysterectomy for endometrial cancer in the United States. Black and Latina women have a higher risk of postoperative complications and serious adverse events compared to white women, and black women have longer hospital stays.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Medicine, General & Internal
Jean-Eric Tarride, Aristithes G. Doumouras, Dennis Hong, J. Michael Paterson, Semra Tibebu, Francis Nguyen, Richard Perez, Valerie H. Taylor, Feng Xie, Vanessa Boudreau, Eleanor Pullenayegum, David R. Urbach, Mehran Anvari
Summary: This study compared 4-year health care expenditures after RYGB and sleeve gastrectomy, finding no significant differences in all-cause mortality and number of hospital admissions between the two procedures, but more frequent nonelective hospitalizations with RYGB. Patients who underwent RYGB had a lower rate of subsequent bariatric procedures.
Article
Oncology
Willem Jan van Weelden, Reini Bretveld, Andrea Romano, Stephan van Erp, Sam Engels, Roy Lalisang, Johanna Pijnenborg, Maaike van der Aa
Summary: The study found significant trends in the incidence rate of endometrioid endometrial cancer over the past few decades, with an increase in the use of hormonal therapy in young and elderly patients. Additionally, adjuvant hormonal treatment was primarily used in patients with advanced stage endometrial cancer.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Surgery
Francesco Guerrera, Paraskevas Lyberis, Paolo Olivo Lausi, Riccardo Carlo Cristofori, Roberto Giobbe, Massimo Molinatti, Pier Luigi Filosso, Carlo Curcio, Roberto Crisci, Enrico Ruffini
Summary: The study found that morbid obesity was associated with a higher rate of complications during VATS lobectomy, but did not lead to higher rates of conversion or surgical margin positivity. Additionally, morbidly obese patients showed similar outcomes in terms of surgical time, lymph-node retrieval, intraoperative blood loss, hospital postoperative length of stay, and chest tube duration compared to non-morbid obese patients. Postoperative complications in morbidly obese patients were primarily pulmonary-related.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Nutrition & Dietetics
Karolina Hoffmann, Anna Paczkowska, Wieslaw Bryl, Kinga Marzec, Jonas Raakow, Matthias Pross, Rafael Berghaus, Elzbieta Nowakowska, Krzysztof Kus, Michal Michalak
Summary: This study compares the level of discrimination among obese patients in Poland and Germany and finds that obesity significantly affects the social and economic well-being of patients. The study suggests the need to reduce weight stigma and alleviate the socioeconomic and psychological burden of obesity.
Review
Medicine, General & Internal
Emma J. Crosbie, Sarah J. Kitson, Jessica N. McAlpine, Asima Mukhopadhyay, Melanie E. Powell, Naveena Singh
Summary: Endometrial cancer is the most common gynaecological cancer in high income countries, with a global rise in incidence. Obesity is the major underlying cause, posing challenges for diagnosis and treatment. Early presentation with postmenopausal bleeding ensures cure, but advanced cases have poor prognosis. Minimally invasive surgical staging and targeted chemotherapeutic strategies are important advances.
Article
Obstetrics & Gynecology
Marissa H. Platner, Christina M. Ackerman, Renata E. Howland, Jessica Illuzzi, Uma M. Reddy, Ghada Bourjeily, Xiao Xu, Heather S. Lipkind
Summary: This study investigated the relationship between increasing classes of obesity and the risk of severe maternal morbidity at delivery hospitalization, finding a significant dose-response relationship with higher risks for super obesity. Women with obesity classes II, III, and super obesity were all significantly more likely to experience severe maternal morbidity than normal weight or overweight women. This highlights the importance of counseling women with prepregnancy obesity on specific risks associated with pregnancy to optimize outcomes.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Endocrinology & Metabolism
Dag Holmberg, Giola Santoni, Joonas H. Kauppila, Sheraz R. Markar, Jesper Lagergren
Summary: This study compared the long-term survival rates of sleeve gastrectomy and gastric bypass in obese patients and found that the overall survival rate of sleeve gastrectomy is comparable to gastric bypass and may even be better in recent years. Additionally, patients with diabetes had a higher all-cause mortality rate after sleeve gastrectomy compared to gastric bypass.
Article
Obstetrics & Gynecology
Koji Matsuo, Rachel S. Mandelbaum, David J. Nusbaum, Shinya Matsuzaki, Maximilian Klar, Lynda D. Roman, Jason D. Wright
Summary: The study revealed that the rates of obesity and morbid obesity have significantly increased among women undergoing benign hysterectomy in the USA, leading to higher risks of perioperative complications and total charges. National and society-based approaches are necessary to reduce the obesity rate and improve hysterectomy outcomes.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Endocrinology & Metabolism
Rinki Murphy, Lindsay D. Plank, Michael G. Clarke, Nicholas J. Evennett, James Tan, David D. W. Kim, Richard Cutfield, Michael W. C. Booth
Summary: SR-LRYGB provided superior diabetes remission and weight loss compared with LSG at 5 years, with similar low risks of complications.
Article
Medicine, General & Internal
Brianna N. Lauren, Francesca Lim, Abraham Krikhely, Elsie M. Taveras, Jennifer A. Woo Baidal, Brandon K. Bellows, Chin Hur
Summary: This study evaluated the cost-effectiveness of medical therapy, sleeve gastrectomy (SG), and Roux-en-Y gastric bypass (RYGB) in patients with severe obesity and type 2 diabetes (T2D). The results showed that RYGB is the most cost-effective treatment strategy, resulting in the highest number of quality-adjusted life-years (QALYs) gained.
Article
Medicine, General & Internal
Regina Sierzantowicz, Jerzy R. Ladny, Krzysztof Kurek, Jolanta Lewko
Summary: This study aimed to analyze the pathologies on preoperative EGD in patients qualified for bariatric surgeries. The results showed that patients with obesity had a higher prevalence of esophageal pathologies compared to the control group, while the control group was more likely to have duodenal pathologies. Additionally, patient sex was a significant predictor of duodenal pathologies.
JOURNAL OF CLINICAL MEDICINE
(2021)