Article
Food Science & Technology
Ruth Naomi, Rusydatul Nabila Mahmad Rusli, Santhra Segaran Balan, Fezah Othman, Azmiza Syawani Jasni, Siti Hadizah Jumidil, Hasnah Bahari, Muhammad Dain Yazid
Summary: E. tapos is a natural plant with various health benefits. This study formulated its extract into yoghurt and evaluated its toxicological effects on rodents. The results showed that the E. tapos yoghurt did not exhibit any toxicity at high doses and had no adverse effects on the physiological indicators and organs of the rats.
Review
Medicine, General & Internal
Aamer Imdad, Samuel P. Mackoff, David M. Urciuoli, Tamkeenat Syed, Emily E. Tanner-Smith, Dongmei Huang, Oscar G. Gomez-Duarte
Summary: This review evaluated evidence on secondary preventative strategies for HUS associated with STEC infections, finding uncertainty in the effectiveness and safety of interventions to prevent development of HUS in patients with diarrhoea due to STEC infection. Additional studies, including larger multicentre studies, are needed to draw firm conclusions about the efficacy of these interventions.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Environmental Sciences
Kannan Kamala, Shanmugam Rajeshkumar, Pitchiah Sivaperumal
Summary: The study revealed the contamination of Shiga toxin-producing Escherichia coli (STEC) in the marine environment along the Southeast Coast of India, with non-STEC isolates playing a key role in environmental and public health. The findings underscore the need for further research into the pathogenic mechanism of STEC.
MARINE POLLUTION BULLETIN
(2022)
Article
Multidisciplinary Sciences
Helena Dela, Beverly Egyir, Ayodele O. Majekodunmi, Eric Behene, Clara Yeboah, Dominic Ackah, Richard N. A. Bongo, Bassirou Bonfoh, Jakob Zinsstag, Langbong Bimi, Kennedy Kwasi Addo
Summary: This study determined the presence of diarrhoeagenic Escherichia coli (DEC) and Extended Spectrum Beta-Lactamase-Producing Enterobacteriaceae (ESBL-PE) and their antimicrobial resistance patterns among diarrhoea patients in two healthcare facilities in Ghana. The findings showed that the high prevalence of ESBL-PE strains among stool isolates limits the treatment options for diarrhoeal patients, highlighting the importance of routine laboratory testing and strengthened surveillance systems in healthcare facilities.
Article
Food Science & Technology
Lanlin Yu, Su Zhang, Yuanyuan Xu, Xiaoyu Mi, Tong Xing, Jiaolong Li, Lin Zhang, Feng Gao, Yun Jiang
Summary: Shiga toxin-producing Escherichia coli (STEC) strains, classified as important foodborne pathogens, exhibited inhibited growth in lactic acid-supplemented medium. Transcriptomic analysis revealed similar responses in acid resistance mechanisms of strains O157 and O26, with O157 showing stronger acid resistance capability and enhanced cysteine biosynthesis playing a crucial role in long-term acid treatment. This study sheds light on deciphering the acid resistance mechanisms of microbes over time and provides insights for better control of microbial-induced food contamination.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Rebecca A. A. Bova, Andrew C. C. Lamont, Theodore J. J. Picou, Vincent B. B. Ho, Kristin H. H. Gilchrist, Angela R. R. Melton-Celsa
Summary: Shiga toxins can cross the intestinal barrier and target kidney endothelial cells, and Stx2a translocates more than Stx1a in both single-layer and three-layer cell models. Infection with different strains of STEC affected barrier function differently, with O157:H7 reducing function and O26:H11 allowing translocation without reducing function.
Review
Dermatology
Lingfeng Pan, Haiyan Qin, Caihong Li, Liehao Yang, Mingxi Li, Jiao Kong, Guang Zhang, Lianbo Zhang
Summary: This study found that BTXA is safe and effective in preventing and treating scar hypertrophy in animal models, but excessive doses and treatment of large areas with BTXA should be avoided.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Gastroenterology & Hepatology
Ida Arvidsson, Ashmita Tontanahal, Karl Johansson, Ann-Charlotte Kristoffersson, Sara Kellnerova, Michael Berger, Ulrich Dobrindt, Diana Karpman
Summary: Apyrase reduces bacterial RecA and toxin release, protects mouse intestinal cells, and decreases platelet activation.
Article
Infectious Diseases
Momna Rubab, Deog-Hwan Oh
Summary: The study investigated the antibiotic resistance of Shiga toxin-producing Escherichia coli (STEC) isolates, finding that most strains exhibited phenotypic resistance, with common resistant genes including ere(A), aadA1, and aac(3)-I. These results underscore the importance of monitoring multidrug resistance globally.
Article
Microbiology
Connor D. LaMontagne, Elizabeth C. Christenson, Anna T. Rogers, Megan E. Jacob, Jill R. Stewart
Summary: The study found a correlation between resistance bacteria and the presence of virulence genes in the environment. It also revealed a negative correlation between antibiotic resistance and the presence of virulence genes. Although no significant association was found between commercial hog operations and virulence, some sub-significant associations should be further studied.
Article
Environmental Sciences
Lingmei Sun, Kai Liao, Dayong Wang
Summary: The study found that surface amino modification can enhance the transgenerational toxicity of nanoplastics, negatively impacting the reproductive capacity and gonad development of organisms. Amino modified nanoplastics showed more severe toxic effects on organisms compared to pristine nanopolystyrene.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Immunology
Ashmita Tontanahal, Vanessa Sperandio, Olga Kovbasnjuk, Sebastian Loos, Ann-Charlotte Kristoffersson, Diana Karpman, Ida Arvidsson
Summary: This study investigated the effect of immunoglobulins (IgG) treatment on a mouse model of E. coli O157:H7 infection. The results showed that IgG treatment improved survival, reduced intestinal and renal pathology, and improved kidney function in infected mice. It was also found that IgG bound to the virulence factor EspP, blocking its enzymatic activity and protecting the host from infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Microbiology
Ikechukwu Oguadinma, Abhinav Mishra, Govindaraj Dev Kumar
Summary: This study evaluated the tolerance of antibiotic resistant bacteria to sanitizers and found that resistance to antibiotics may compromise mitigation strategies against pathogens.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Saroj Rai, M. Kumar, R. Jas, G. P. Mandal, I. Samanta, M. Rajendar, S. Tripura, S. K. Das, M. Mondal, D. K. Mandal
Summary: Calf diarrhoea remains a major challenge in both small and large farms. A study is investigating the use of popular kitchen herbs such as carom seeds, turmeric, and cinnamon extracts as alternative prophylactic solutions against virulent E. coli causing calf diarrhoea, due to the increasing antimicrobial resistance. The extracts showed inhibitory effects on E. coli, indicating their potential use in calf diets to prevent diarrhoea.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2023)
Article
Food Science & Technology
Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesus del Mazo, Bettina Grasl-Kraupp, Christer Hogstrand, Jean-Charles Leblanc, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Sven Daenicke, Carlo Stefano Nebbia, Isabelle P. Oswald, Elena Rovesti, Hans Steinkellner, Laurentius (Ron) Hoogenboom
Summary: In 2011, EFSA adopted a Scientific Opinion on the risks of T-2 and HT-2 toxins in food and feed for animal health. The study concluded that rumen detoxification of T-2 may not always be complete in ruminants, leading to potential adverse effects. However, data on the effects of T-2 on adult ruminants were limited, and further research is needed.
Article
Immunology
V. Sharma, P. Kaur, R. S. Aulakh, R. Sharma, R. Verma, B. B. Singh
Summary: Brucellosis is a neglected zoonosis that affects animals and people in the underdeveloped world. This study aimed to isolate and identify Brucella species from faeces of sero positive cattle in Punjab, India. Fourteen Brucella species were isolated, with 11 identified as Brucella abortus and 3 identified as Brucella melitensis. The study highlights the potential risk of animal faeces for animal and human health and emphasizes the need for careful handling of faeces from seropositive cattle.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2024)
Article
Immunology
Yilei Zhang, Guojun Chen, Siyi Zhou, Lingru He, Olalekan Opeyemi Ayanniyi, Qianming Xu, Zhenyu Yue, Congshan Yang
Summary: The development of the Animal Parasitic Diseases and Drugs Database (APDDD) provides a comprehensive and intuitive tool for studying animal parasitic diseases and antiparasitic drugs, allowing users to understand the relationships between parasitic diseases, drugs, and targeted genes more effectively.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2024)
Article
Immunology
Arthur Nery Finatto, Sulove Koirala, Fernanda Luiza Facioli, Jessica Aparecida Barbosa, Roman Nosach, Matheus de Oliveira Costa
Summary: The study revealed that Streptococcus equi subsp. zooepidemicus rapidly disseminated in various organs of pigs following oronasal inoculation, with tonsil samples consistently harboring the pathogen throughout the study period. The varying bacterial loads in mesenteric lymph nodes indicated persistence, replication, and a potential source for shedding.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2024)