Review
Cell Biology
Jinju Lin, Qin Li, Xiaohua Lei, Huashan Zhao
Summary: GPR158 is a G protein-coupled receptor that is highly expressed in the central nervous system and lowly expressed in peripheral tissues. Previous studies have focused on its functions in the CNS, while limited research has been done on its role in the non-nervous system. Recent studies have shown that GPR158 is involved in adrenal regulation, suggesting its role in peripheral tissues. Furthermore, GPR158 forms a complex with RGS7-G beta 5, which is implicated in endocrine functions.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
David Munoz, Ricardo Fuentes, Beatriz Carnicero, Andrea Aguilar, Nataly Sanhueza, Sergio San-Martin, Cristian Agurto, Andrea Donoso, Leonardo E. Valdivia, Jesus M. Miguez, Lluis Tort, Sebastian Boltana
Summary: Feeding behavior in fish is influenced by multiple signals in the brain, with stress cues such as viral infection triggering responses from hypothalamic neurons to regulate energy storage and expenditure. This study provides evidence of a molecular linkage between inflammation and food intake in Salmon salar, highlighting the importance of understanding the interplay between energy homeostasis and pathogenesis in fish.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Entomology
Christopher J. Holmes, Elliott S. Brown, Dhriti Sharma, Matthew Warden, Atit Pathak, Blaine Payton, Quynh Nguyen, Austin Spangler, Jaishna Sivakumar, Jacob M. Hendershot, Joshua B. Benoit
Summary: Female mosquitoes have adapted to bloodfeeding on humans, especially in drier areas. These mosquitoes can quickly rehydrate through bloodfeeding, potentially resulting in altered disease transmission rates. Further research is needed to understand how these mosquitoes process bloodmeals in low humidity conditions.
Review
Chemistry, Physical
Danping Sun, Zhi Tan, Xuzheng Tian, Fei Ke, Yale Wu, Jin Zhang
Summary: Graphene, as a promising charge regulation material in high-performance LIBs, shows great potential due to its excellent carrier mobility and large specific surface area. Recent research has focused on the structural design and interfacial modification of graphene to effectively control charge transport in LIBs. Understanding the structure-performance relationships of graphene in dedicated applications for LIBs will pave the way for the development of next-generation electrochemical energy storage devices.
Article
Cell Biology
Lei He, Binbin Wu, Jian Shi, Juan Du, Zhangwu Zhao
Summary: Gart positively regulates feeding behavior through cooperation and coordination in the glia, fat body, and gut. It is crucial for maintaining endogenous feeding rhythms and food intake, as well as regulating energy homeostasis between synthesis and metabolism. Gart expression is directly controlled by the CLOCK/CYCLE heterodimer and impacts Drosophila lifespan.
Review
Plant Sciences
Cynthia Wong, David Alabadi, Miguel A. Blazquez
Summary: Plant hormones can act in the cells where they are produced, but also function as signaling molecules to coordinate physiological responses between different parts of the plant. The spatial ranges of hormone action are determined by metabolism, transport, and perception/signal transduction pathways.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Engineering, Chemical
Harm T. M. Wiegerinck, Reinder Kersten, Jeffery A. Wood
Summary: This work investigates the influence of charge regulation on the performance of a shock electrodialysis cell. The results show that including charge regulation requires higher potentials to achieve the same degree of desalination compared to the constant surface charge model. It also highlights the potential for substantial Joule heating and temperature increases at higher potentials.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Engineering, Chemical
Harm T. M. Wiegerinck, Reinder Kersten, Jeffery A. Wood
Summary: Numerous theoretical studies have been conducted to better understand the ion transport in a continuous cross-flow shock electrodialysis process. These studies have assumed a constant surface charge, but this work considers the influence of charge regulation caused by changes in salt concentration. The results indicate that including charge regulation requires higher potentials to achieve the same degree of desalination, and operating at higher potentials can lead to substantial Joule heating and temperature increases. The required energy input for desalination is still much higher than the thermodynamic minimum even in the nonisothermal case with charge regulation. This highlights the importance of charge regulation in a shock electrodialysis process.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Jasmin Ballout, Rebecca Classen, Katrin Richter, Veronika Grau, Martin Diener
Summary: This study found that ionotropic P2X receptors are involved in the regulation of intestinal ion transport in rat colonic epithelia.
BRITISH JOURNAL OF PHARMACOLOGY
(2022)
Review
Physiology
Kuang-Yu Tseng, Jyuan-Ru Tsai, Hui-Chen Lin
Summary: Crabs inhabit various habitats with diverse osmoregulatory patterns. Gills, antennal glands, and a lung-like structure are important organs for maintaining homeostasis in crabs. Different species use different processes to regulate ion concentrations in the antennal gland, especially those with high terrestriality. The study found a correlation between antennal gland NKA activity and urine-hemolymph ratio for Na+ concentration in hypo-osmotic environments among crabs. However, there is limited research on the structural and functional differences in the antennal gland among brachyurans. Next-generation sequencing and proteomics methods can be used to further investigate the phylogenetic history of crab antennal glands.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Meredith M. Ogle, Rolando Trevino, Joseph Schell, Mahboubeh Varmazyad, Nobuo Horikoshi, David Gius
Summary: The dysregulation of cellular and mitochondrial antioxidants can lead to oxidative damage and tumor development. Disruption of mitochondrial networks is a characteristic of cancer and therapy resistance. Loss or disruption of manganese superoxide dismutase may be an early event or a promoter of tumor development.
Article
Geriatrics & Gerontology
V. D. K. Reddy, Minurani Dalai, M. Sultan Khan, Anita Jagota
Summary: The circadian timing system is synchronized by environmental signals, primarily light, and non-photic cues may play a major role in synchronizing the clock under aging condition. This study investigates the effects of time-restricted feeding (TRF) as a non-photic stimulus on serotonin and its related metabolites in the suprachiasmatic nucleus (SCN) and pineal gland of aging rats. The results show that TRF can synchronize the age-induced desynchronization in serotonin metabolome.
Review
Biochemistry & Molecular Biology
Shuangshuang Zhao, Qikun Zhang, Mingyue Liu, Huapeng Zhou, Changle Ma, Pingping Wang
Summary: Plants adapt to high-salt environments by regulating ion balance, activating osmotic stress pathways, mediating plant hormone signaling, and adjusting cytoskeleton dynamics and cell wall composition in response to salt stress signals. Understanding these mechanisms is crucial for improving agricultural crop yields.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Daniel Khananshvili
Summary: Na+/Ca2+ exchangers mediate Ca2+ extrusion/entry to shape Ca2+ signaling in biological systems. Selective targeting of NCX variants with pharmacological agents could have clinical benefits. This article summarizes the relevant issues for future developments, considering the limited understanding of NCX molecular structure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, Research & Experimental
Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, Gerard Karsenty
Summary: This study reveals the importance of a bone-derived embryonic hormone, osteocalcin, in regulating lifelong adrenal functions and organismal homeostasis in mice.
JOURNAL OF CLINICAL INVESTIGATION
(2022)
Review
Biology
Adalberto Luis Val, Chris M. Wood
Summary: The Amazon region is a unique area in the world, with rich freshwater fish resources, but is currently facing a serious crisis due to climate change and human activities.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Biology
Chris M. Wood, Beverly H. K. Po
Summary: This study found that the green crab exhibits both terrestrial and emersion activity during low tide. Treadmill exercise in air showed an inverse relationship between velocity and duration. The recovery process after exercise in air was more pronounced and lasting, including metabolic disturbances and acid-base recovery.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Biology
Junho Eom, Henrik Lauridsen, Chris M. Wood
Summary: This study examines the feeding and breathing mechanisms of the Pacific hagfish, Eptatretus stoutii, using various methods including video, respirometry, and imaging techniques. The results provide insights into the relationship between the nostril, velum chamber, and food passage, as well as the processes of swallowing and defecation. Furthermore, it reveals an increase in oxygen consumption rate after feeding, which lasts for a prolonged period.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Marine & Freshwater Biology
John O. Onukwufor, Chris M. Wood
Summary: This study investigates the differential effects of acute temperature, salinity, and oxygen levels on the diffusive water flux and oxygen uptake of English sole and Pacific sanddab. The results suggest that both species exhibit similar responses to acute hypoxia, but differ in their sensitivity to acute temperature and salinity changes.
Article
Fisheries
Peter Elliot Holder, Chris M. Wood, Michael J. Lawrence, Timothy D. Clark, Cory D. Suski, Jean-Michel Weber, Andy J. Danylchuk, Steven J. Cooke
Summary: Post-exercise mortality (PEM) can occur in fish when they exercise to exhaustion and surpass their physiological limits, leading to death. The causes of PEM are not fully understood, but studies have explored factors such as oxygen delivery, ion regulation, hormone signalling, and cardiac function. Improved data collection methods and experimental protocols have contributed to our understanding of PEM and have informed management actions. While progress has been made, there is still much to uncover through future research.
FISH AND FISHERIES
(2022)
Article
Physiology
Marina Giacomin, Patricia M. Schulte, Chris M. Wood
Summary: The osmorespiratory compromise in fishes refers to the trade-off between respiratory gas exchange and osmolyte/water balance at the gills. Exhaustive exercise in Pacific spiny dogfish led to increased oxygen consumption and ammonia losses, while urea-N losses were tightly regulated. Environmental hyperoxia did not alleviate the effects of the compromise.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2022)
Article
Physiology
Giorgi Dal Pont, Beverly Po, Jun Wang, Chris M. Wood
Summary: The physiological responses of Carcinus maenas to different salinity conditions were evaluated, and wide plasticity and tolerance to disturbances in physiological parameters were observed, suggesting that this species is well adapted to diverse habitats.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2022)
Article
Environmental Sciences
Anne Cremazy, Susana Braz-Mota, Kevin V. Brix, Rafael M. Duarte, Adalberto L. Val, Chris M. Wood
Summary: This study investigated the effects of natural dissolved organic matter (DOM) on the acute copper toxicity to local fish in the Rio Negro. The results showed that DOM can decrease the bioavailability and toxicity of copper to fish. Additionally, DOM was found to protect against copper uptake and toxicity in the fish. These findings support the use of the Biotic Ligand Model to assess the risk of copper in Amazonian waters.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Zoology
Ellen H. Jung, Jessica Nguyen, Charlotte Nelson, Colin J. Brauner, Chris M. Wood
Summary: The gastrointestinal tract plays a crucial role in nitrogen metabolism in rainbow trout, with the stomach being an important site for independent ammonia absorption and transport.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2023)
Article
Zoology
Chris M. Wood
Summary: This study examined the nitrogen waste metabolism in green crabs and found that exercise and emersion had a significant impact on the ammonia(N) excretion rate, but the excretion of urea(N) and urate(N) also indicated their importance. In addition, the study found that the concentrations of ammonia(N) and PNH3 in the hemolymph were higher than in the BCF, and the volume of BCF decreased significantly after emersion and exercise.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2023)
Article
Biology
Helen Sadauskas-Henrique, Ora E. Johannsson, Beverly H. K. Po, Adalberto L. Val, Chris M. Wood
Summary: The green crab is affected by intertidal zonation patterns, facing periods of air and water exposure. During these periods, physiological challenges are faced. Oxygen consumption rate remained unchanged during air exposure, but increased during recovery period. Ammonia and urea excretion rates were reduced during air exposure, but rebounded during recovery.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2023)
Article
Entomology
Cole Baril, Christophe M. R. LeMoine, Bryan J. Cassone
Summary: In this study, the novel black queen cell virus (BQCV) was identified in mosquitoes collected from Manitoba, Canada. The nearly complete genome sequence of BQCV was obtained, revealing its high similarity to a BQCV isolate from Sweden. It is hypothesized that mosquitoes acquired the virus indirectly through foraging at the same nectar sources as honeybees.
JOURNAL OF INSECT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
John O. O. Onukwufor, Derek A. A. Somo, Jeffrey G. G. Richards, Chris M. M. Wood
Summary: In nature, mosshead sculpins face challenges from temperature and oxygen level fluctuations. The sculpins are able to modulate the permeability of their branchial epithelia in response to temperature stress, but not in response to hypoxia and re-oxygenation stress. This contrasts with the responses observed in a similar fish species with lower hypoxia tolerance. Overall, the data suggests a decoupling between diffusive water flux rates and oxygen consumption rates during hypoxia stress.
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Junho Eom, Chris M. Wood
Summary: A new less invasive device incorporating an ultrasonic flow probe and a divided chamber was used to measure ventilatory flow rate and % O-2 utilization in rainbow trout after exercise and feeding. The study found that respiration in trout is more efficient than previously believed.
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Marine & Freshwater Biology
Carolyn Morris, Chris M. Wood
Summary: Marine flatfishes show changes in diffusive water flux and ammonia excretion rates as salinity decreases, while oxygen consumption and urea-N excretion rates remain relatively stable. The increase in diffusive water flux is primarily caused by reduced [Ca2+], rather than reduced salinity itself. Our results suggest that both diffusive water flux and ammonia excretion rates are influenced by salinity and ambient [Ca2+].
Article
Biochemistry & Molecular Biology
Diana Medina-Felix, Francisco Vargas-Albores, Estefania Garibay-Valdez, Luis Rafael Martinez-Cordova, Marcel Martinez-Porchas
Summary: In this research, the effects of Nocardia infection on fish gastrointestinal microbiota were analyzed. It was found that the infection led to decreased survival rate, severe damage to the stomach microbiota, and a significant increase in Proteobacteria. A negative correlation network between Proteobacteria and other important phyla was observed. Therefore, Nocardia sp. is an emerging pathogen capable of inducing dysbiosis and causing significant mortalities.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2024)
Article
Biochemistry & Molecular Biology
Lele Wu, Wen Sun, Jiale Zhou, Yaolin Li, Jun Li, Zongcheng Song, Changbin Song, Shihong Xu, Xinlu Yue, Xian Li
Summary: The study finds that red light induces dichromatic skin pigmentation in turbot juveniles, with some individuals displaying black coloration and others displaying lighter skin. The upregulated gene expressions related to melanin synthesis and the involvement of the nervous system in spectral environment-driven color regulation are both crucial factors.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2024)