Journal
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Volume 151, Issue 2, Pages 225-229Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cbpb.2008.07.006
Keywords
Fenneropenaeus chinensis; haernatopoietic tissue; PCNA; Vibrio challenge; WSSV challenge
Categories
Funding
- Major State Basic Research Development Program of China [2006CB101804]
- High-Tech Research and Development Program of China [2006AA09Z424]
- National Natural Science Foundation of China [30471347]
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The proliferating cell nuclear antigen gene was cloned from Fenneropenaeus chinensis (FcPCNA). The full-length cDNA sequence of FcPCNA encodes 260 amino acids showing high identity with PCNAs reported in other species. FcPCNA expressed especially high in proliferating tissues of shrimp such as haematopoietic tissue (HPT) and ovary. In order to understand the response of HPT to bacteria and virus challenge, mRNA level of FcPCNA in HPT was analyzed after shrimp were challenged by Vibrio anguillarum and white spot syndrome virus (WSSV). FcPCNA expression in HPT of shrimp was responsive to WSSV and Vibrio challenge, but different expression profiles were obtained after challenge by these two pathogens. The data provide additional information to understand the defense mechanisms of shrimp against virus and bacteria. (c) 2008 Elsevier Inc. All rights reserved.
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