Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)

Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression

(2015) Li-Na Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Poly(A)-specific ribonuclease deficiency impacts telomere biology and causes dyskeratosis congenita

(2015) Hemanth Tummala et al.   JOURNAL OF CLINICAL INVESTIGATION

Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening

(2015) Bridget D Stuart et al.   NATURE GENETICS

Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease

(2014) Mary McMahon et al.   Wiley Interdisciplinary Reviews-RNA

Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients

(2013) L. Garcon et al.   BLOOD

Poly(A)-specific ribonuclease (PARN): An allosterically regulated, processive and mRNA cap-interacting deadenylase

(2013) Anders Virtanen et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Ccr4-Not deadenylase complex constitutes the main poly(A) removal activity in C. elegans

(2013) M. Nousch et al.   JOURNAL OF CELL SCIENCE

Molecular characteristics of a pancreatic adenocarcinoma associated with Shwachman-Diamond syndrome

(2013) Santhosh Dhanraj et al.   PEDIATRIC BLOOD & CANCER

Novel small Cajal-body-specific RNAs identified in Drosophila: probing guide RNA function

(2013) S. Deryusheva et al.   RNA

Poly(A)-Specific Ribonuclease Mediates 3′-End Trimming of Argonaute2-Cleaved Precursor MicroRNAs

(2013) Mayuko Yoda et al.   Cell Reports

Impaired ribosomal subunit association in Shwachman-Diamond syndrome

(2012) N. Burwick et al.   BLOOD

Modulation of Poly(A)-specific Ribonuclease (PARN): Current Knowledge and Perspectives

(2012) N. A.A. Balatsos et al.   CURRENT MEDICINAL CHEMISTRY

Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming

(2012) H. Berndt et al.   RNA

The PARN Deadenylase Targets a Discrete Set of mRNAs for Decay and Regulates Cell Motility in Mouse Myoblasts

(2012) Jerome E. Lee et al.   PLoS Genetics

Collapse of Telomere Homeostasis in Hematopoietic Cells Caused by Heterozygous Mutations in Telomerase Genes

(2012) Geraldine Aubert et al.   PLoS Genetics

The ribosome-related protein, SBDS, is critical for normal erythropoiesis

(2011) S. Sen et al.   BLOOD

cpsf1 is required for definitive HSC survival in zebrafish

(2011) N. Bolli et al.   BLOOD

NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis

(2011) A. Michael Forrester et al.   BRITISH JOURNAL OF HAEMATOLOGY

Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome

(2011) A. J. Finch et al.   GENES & DEVELOPMENT

Genetic analysis of inherited bone marrow failure syndromes from one prospective, comprehensive and population-based cohort and identification of novel mutations

(2011) E. Tsangaris et al.   JOURNAL OF MEDICAL GENETICS

Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants

(2011) Dalila Pinto et al.   NATURE BIOTECHNOLOGY

Non-coding RNAs as regulators of embryogenesis

(2011) Andrea Pauli et al.   NATURE REVIEWS GENETICS

Defective Mitochondrial mRNA Maturation Is Associated with Spastic Ataxia

(2010) Andrew H. Crosby et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

(2009) D. J. Stumpo et al.   BLOOD

Recognition of Adenosine Residues by the Active Site of Poly(A)-specific Ribonuclease

(2009) Niklas Henriksson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of m7GpppG Binding to Poly(A)-Specific Ribonuclease

(2009) Mousheng Wu et al.   STRUCTURE

SBDS-deficiency results in specific hypersensitivity to Fas stimulation and accumulation of Fas at the plasma membrane

(2008) Ken-ichiro Watanabe et al.   APOPTOSIS

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

(2008) Trilochan Sahoo et al.   NATURE GENETICS

Clinical and Genetic Analysis of Unclassifiable Inherited Bone Marrow Failure Syndromes

(2008) J. T. Teo et al.   PEDIATRICS

Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP

(2008) C. Trahan et al.   RNA

Cartilage–hair hypoplasia-associated mutations in the RNase MRP P3 domain affect RNA folding and ribonucleoprotein assembly

(2007) Tim J.M. Welting et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH