Article
Surgery
Andreas Jonsson, Peter Falk, Eva Angenete, Claes Hjalmarsson, Marie-Lois Ivarsson
Summary: The study showed that a high level of MMP-1 in circulating plasma was associated with a poorer prognosis in colon cancer, which may be important for discussing prognosis and selecting patients for treatment and surveillance.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Oncology
Ruitong Xu, Bingrong Zhou, Ping Hu, Bingyan Xue, Danyang Gu, Xiaolin Li, Qiyun Tang
Summary: This study conducted a retrospective analysis of 1196 patients with colon neuroendocrine neoplasms, and developed and validated nomograms containing various clinically important parameters to predict the prognosis more accurately. The new nomograms showed superior performance in predicting overall survival and cancer-specific survival compared to the AJCC TNM classification.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Dae Hee Pyo, Seok-Hyung Kim, Jung Kyong Shin, Yoonah Park, Jung Wook Huh, Hee Cheol Kim, Seong Hyeon Yun, Woo Yong Lee, Yong Beom Cho
Summary: This study found that micropapillary pattern-positive status may serve as an independent prognostic factor for colon cancer, especially for patients with stage II disease. This result contributes to a better understanding of prognostic markers and treatment strategies for colon cancer.
DISEASES OF THE COLON & RECTUM
(2023)
Article
Oncology
Mingkun Zhang, Yuan Qin, Niuniu Hou, Fuqing Ji, Zhihao Zhang, Juliang Zhang
Summary: This study aimed to establish a nomogram for accurately predicting the overall survival (OS) of patients with non-metastatic invasive micropapillary breast carcinoma (IMPC). Data from 429 patients in the Surveillance, Epidemiology, and End Results (SEER) database were analyzed to establish a nomogram for predicting OS at 3, 5, and 8 years. The nomogram showed good calibration and predictive accuracy in both the training and validation cohorts, and could help optimize treatment strategies based on individual risk factors.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Agata Mormul, Emilia Wloszek, Julia Nowoszewska, Marta Fudalej, Michal Budzik, Anna Badowska-Kozakiewicz, Andrzej Deptala
Summary: Pancreatic ductal adenocarcinoma is the most common pancreatic tumor, accounting for 85% of cases. The remaining 15% consists of various rare neoplasms. This study gathered the latest data on the epidemiology, diagnosis, biomarkers, and management of six rare pancreatic tumors to provide important insights for their proper classification and treatment.
Article
Surgery
Man Fung Ho, Victoria Cindy Lai, Dennis Chung Kei Ng, Simon Siu Man Ng
Summary: Aim: To compare the survival factors of patients with unresectable stage IV colon cancer treated with primary tumor resection (PTR) as the first treatment or conventional palliative chemotherapy. Methodology: Patients with minimally or asymptomatic stage IV colon cancer were identified from databases in different centers from 2015 to 2020. The patients were followed up based on whether they underwent PTR. The primary end point was overall survival, and risk factors affecting survival were analyzed using statistical methods. Results: The study included 162 patients. Cox regression analysis found that PTR, bone metastasis, commencement, and completion of systemic therapy were independent factors predicting survival. The median overall survival after PTR vs tumor in-situ was 28 vs 12 months. Conclusion: Resection of the primary tumor is an independent prognostic factor for relatively asymptomatic stage IV colon cancer patients with unresectable metastasis.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seo-Youn Choi, Jung Hoon Kim, Sanghyeok Lim, Ji Eun Lee, Hyun Jeong Park, Bora Lee
Summary: By analyzing preoperative CT findings, a prognostic nomogram for gallbladder cancer patients can be established, with different types and invasion statuses influencing prognosis.
EUROPEAN RADIOLOGY
(2021)
Article
Oncology
E. Rosander, T. Holm, A. Sjovall, F. Hjern, C. E. Weibull, C. Nordenvall
Summary: This study suggests that preoperative MDT assessment is associated with improved long-term survival in patients with locally advanced colon cancer, and it is recommended to be mandatory in patients with suspected locally advanced colon cancer.
Article
Oncology
Ji Ha Lim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Jung Kyong Shin
Summary: This study compared the oncologic outcomes between patients with incomplete obstructive colon cancer (IOCC) and non-obstructive colon cancer (NOCC) according to tumor location. The results showed that patients with IOCC had significantly worse survival outcomes than those with NOCC. Stage II IOCC patients and stage III NOCC patients had similar survival rates. The location of the tumor, especially on the right side, affected the survival outcomes. These findings highlight the importance of considering incomplete obstruction and tumor location in assessing prognosis for colon cancer patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Seo Hee Choi, Chai Hong Rim, In-Soo Shin, Won Sup Yoon, Woong Sub Koom, Jinsil Seong
Summary: The benefits of adjuvant radiotherapy (ART) in gallbladder cancer (GBC) treatment remain inconclusive. In this study, a systematic review of 21 studies involving GBC patients was conducted. The results showed that ART can significantly reduce locoregional recurrence in GBC patients, but has no significant effect on distant metastasis. Furthermore, ART showed similar survival outcomes in patients with similar or slightly inferior clinical profiles.
HEPATOLOGY INTERNATIONAL
(2022)
Editorial Material
Oncology
Frederick Charles Campbell
Summary: The study investigated the morphological evolution of a highly fatal subtype of colorectal cancer known as micropapillary cancer (MPC). Through iterative modeling in 3D patient-derived CRC tissue-originated spheroids (CTOSs), the study revealed spatiotemporal oscillations of Rho-ROCK hyperactivity underlying membrane polarity reversal and lumen formation suppression. Targeted inhibition of Rho-ROCK activity restored membrane polarity and lumenized multicellular assembly in 3D CTOS cultures and xenografts.
JOURNAL OF PATHOLOGY
(2021)
Article
Oncology
Adriana de Souza Sergio Ferreira, Jane Rocha Duarte Cintra, Vivian Assis Fayer, Mario Cirio Nogueira, Cassimiro Baesso Junior, Maria Teresa Bustamante-Teixeira, Alfredo Chaoubah, Arthur Duarte Cintra, Caroline Montes Simao, Maximiliano Ribeiro Guerra
Summary: In a cancer care center in the Brazilian southeast region, the 5- and 10-year survival rates for breast cancer patients with private healthcare insurance were higher compared to those with public healthcare insurance. The survival rate disparities in breast cancer can be attributed to differences in the stage of the disease at the time of diagnosis, indicating inequalities in access to early detection of breast cancer.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Frans Emland, Helena Taflin, Goran Carlsson, David Ljungman, Elinor Bexe Lindskog
Summary: Prolonged postoperative length of stay (LOS) is associated with increased risk of recurrence and shorter disease-free survival (DFS) in patients with stage III colon cancer, regardless of whether adjuvant chemotherapy is given. Factors such as age, comorbidity, complications, and tumor features also play a role in this correlation.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Atieh Akbari, Maryam Khayamzadeh, Reza Salmanian, Afshin Moradi, Mohammad Esmaeil Akbari
Summary: This study aimed to estimate the survival rate of cervical cancer (CC) and the reasons for its low survival rate based on the data retrieved from the Iranian National Cancer Registry System. The study found that the survival rate of CC in Iran is low and is related to biological factors, geographical, and sociodemographic indices. Effective screening based on cultural and sociodemographic issues is recommended.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Seok Hahn, Kwang-Min Kim, Min-Ju Kim, Hyang-Suk Choi, Hany Noh, In-Jeong Cho, Seung-Taek Lim, Jong-In Lee, Airi Han
Summary: This study aimed to investigate the reciprocal effect of tumor vascularity and host immunity on patient survival in breast cancer patients. The study found that patients had worse survival outcomes when both tumor vascularity and immunity were unfavorable.
Article
Oncology
Luis I. Pozos-Ochoa, Leonardo S. Lino-Silva, Alberto M. Leon-Takahashi, Rosa A. Salcedo-Hernandez
PATHOLOGY & ONCOLOGY RESEARCH
(2018)
Article
Pathology
Leonardo S. Lino-Silva, Rosa A. Salcedo-Hernandez, Patricia Segales-Rojas, Cesar Zepeda-Najar
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
(2018)
Letter
Surgery
Leonardo S. Lino-Silva, Rosa A. Salcedo-Hernandez, Alberto M. Leon-Takahashi
Article
Dermatology
Leonardo S. Lino-Silva, Cesar Zepeda-Najar, Rosa A. Salcedo-Hernandez, Hector Martinez-Said
JOURNAL OF CUTANEOUS MEDICINE AND SURGERY
(2019)
Article
Medical Laboratory Technology
Monica L. Serrano-Arevalo, Lorena Flores-Hernandez, Lidia F. Villegas-Gonzalez, Sandy Zamora-Zarco, Alejandro Espana-Ferrufino, Leonardo S. Lino-Silva, Salim A. Barquet-Munoz
DIAGNOSTIC CYTOPATHOLOGY
(2019)
Article
Oncology
Leonardo S. Lino-Silva, Janet C. Guzman-Lopez, Cesar Zepeda-Najar, Rosa A. Salcedo-Hernandez, Abelardo Meneses-Garcia
JOURNAL OF SURGICAL ONCOLOGY
(2019)
Letter
Pathology
Leonardo S. Lino-Silva, Armando Gamboa-Dominguez, Diego Zuniga-Tamayo, Patricia Lopez-Correa
Article
Oncology
Leonardo S. Lino-Silva, Patricia Anchondo-Nunez, Alonso Chit-Huerta, Estefania Aguilar-Romero, Jonathan Morales-Soto, Jenny A. Salazar-Garcia, Cristina J. Guzman-Lopez, Hector A. Maldonado-Martinez, Abelardo Meneses-Garcia, Rosa A. Salcedo-Hernandez
JOURNAL OF SURGICAL ONCOLOGY
(2019)
Article
Oncology
Leonardo S. Lino-Silva, Diana L. Xinaxtle
Article
Oncology
Jose M. Aguilar-Romero, Estefania Aguilar-Romero, Omar Vergara-Fernandez, Cesar Zepeda-Najar, Leonardo S. Lino-Silva, Rosa A. Salcedo-Hernandez
Summary: Tumor deposits (TDs) are not associated with mortality in rectal cancer patients treated with n-CRT. Factors associated with decreased survival are inadequate mesorectal quality and perineural invasion.
JOURNAL OF GASTROINTESTINAL CANCER
(2023)
Article
Gastroenterology & Hepatology
Leonardo S. Lino-Silva, Carmen I. Sanchez-Acosta, Rosa A. Salcedo-Hernandez, Cesar Zepeda-Najar
GASTROENTEROLOGY INSIGHTS
(2020)
Article
Oncology
Karla J. Gonzalez-Colunga, Leonardo S. Lino-Silva, Rosa A. Salcedo-Hernandez, Erika B. Ruiz-Garcia, Cesar Zepeda-Najar
JOURNAL OF GASTROINTESTINAL CANCER
(2020)
Article
Oncology
Leonardo S. Lino-Silva, Janet C. Guzman-Lopez, Jenny A. Salazar-Garcia, Jazmin D. Chavez-Hernandez, Armando Gamboa-Dominguez, Erwin Chiquete, Alejandro Mohar, Jonathan Morales-Soto, Rosa A. Salcedo-Hernandez
JOURNAL OF GASTROINTESTINAL CANCER
(2020)
Article
Oncology
Patricia Segales-Rojas, Leonardo S. Lino-Silva, Eduardo Aguilar-Cruz, Rosa A. Salcedo-Hernandez
JOURNAL OF GASTROINTESTINAL CANCER
(2018)