Article
Surgery
Johannes M. Salusjarvi, Laura E. Koskenvuo, Juha P. Mali, Panu J. Mentula, Ari K. Leppaniemi, Ville J. Sallinen
Summary: This study retrospectively analyzed patients who underwent Hartmann's procedure for acute diverticulitis between 2006 and 2017, with follow-up until March 2021. The study found that one-third of the patients died, half underwent stoma reversal, and one-fifth did not undergo stoma reversal. Risk factors for non-reversal included old age, a need for outside assistance, low Helsinki Staging for Acute Diverticulitis stage, and higher C-reactive protein level upon hospital admission.
Article
Multidisciplinary Sciences
Jules Le Lay, Edgar Alfonso-Lizarazo, Vincent Augusto, Bienvenu Bongue, Malek Masmoudi, Xiaolan Xie, Baptiste Gramont, Thomas Celarier
Summary: The objective of this study is to understand the characteristics of multimorbid patients who require hospital care and to predict their rehospitalization and length of stay using machine learning models. The results show that the use of random forest algorithms and direct use of diagnoses codes have better predictive performance. However, the predictive power of the algorithms is limited for length of stay.
Article
Medicine, General & Internal
Benjamin Beska, Greg B. Mills, Hanna Ratcovich, Chris Wilkinson, Abdulla A. Damluji, Vijay Kunadian
Summary: In older adults with NSTE-ACS referred for coronary angiography, the presence of multimorbidity is associated with an increased risk of long-term adverse cardiovascular events, mainly driven by a higher risk of all-cause mortality.
Article
Medicine, General & Internal
Paulo Jorge Nogueira, Miguel de Araujo Nobre, Cecilia Elias, Rodrigo Feteira-Santos, Antonio C- Martinho, Catarina Camarinha, Leonor Bacelar-Nicolau, Andreia Silva Costa, Cristina Furtado, Liliane Morais, Juan Rachadell, Mario Pereira Pinto, Fausto Pinto, Anto Vaz Carneiro
Summary: This study aimed to describe the morbidity profile of COVID-19 deaths in Portugal during 2020, finding that deaths primarily occurred in individuals aged 80 years or older, with a slightly higher mortality rate in males. The study observed high levels of comorbidities, with varying prevalence rates of zero morbidity and high multimorbidity throughout the year, especially during peak mortality waves.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Yuto Kubo, Koji Tanaka, Makoto Yamasaki, Kotaro Yamashita, Tomoki Makino, Takuro Saito, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Yukinori Kurokawa, Masaaki Motoori, Yutaka Kimura, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Summary: The study demonstrated that a Charlson Comorbidity Index (CCI) of >= 2 was significantly associated with poor postoperative nutritional indexes at 1 month after surgery for esophageal cancer. This suggests that effective nutritional interventions are necessary for postoperative malnutrition in patients, especially those with multiple comorbidities.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Editorial Material
Health Care Sciences & Services
Allison Drosdowskya, Karla Gougha
Summary: The Charlson Comorbidity Index is a highly cited and well-established tool for measuring comorbidity in clinical research, but there are challenges with its practical application. Researchers should interpret with caution the association between comorbidity and risk of death or survival time, especially if the CCI was used to provide a measure of comorbidities.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Jose-Angel Perez-Rivera, Carlos Arminanzas, Patricia Munoz, Martha Kestler, Blanca Pinilla, Maria-Carmen Farinas, Ignacio Alvarez-Rodriguez, Guillermo Cuervo, Angeles Rodriguez-Esteban, Aristides de Alarcon, Andrea Gutierrez-Villanueva, Ana Pello-Lazaro, Manuel Martinez Selles
Summary: This study aimed to describe the current profile of infective endocarditis (IE) in octogenarians and analyze the impact of baseline comorbidities on prognosis. The results showed that high comorbidities were associated with increased in-hospital and 1-year mortality in older patients with IE. The study also found that the performance of cardiac surgery in this group of patients was suboptimal, potentially contributing to their poor prognosis.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Yun-Ju Huang, Jung-Sheng Chen, Shue-Fen Luo, Chang-Fu Kuo
Summary: The study showed a high comorbidity burden in patients with rheumatoid arthritis, and the changes in comorbidity indexes were associated with mortality prediction.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Ahmet Balun, Alkame Akgumus
Summary: Elderly patients with acute coronary syndrome (ACS) are more fragile due to the burden of comorbidity. The Charlson Comorbidity Index (CCI) was used to assess the impact of comorbidity on 1-year mortality and clinical outcomes in elderly ACS patients who underwent percutaneous coronary intervention. Higher CCI scores were associated with increased stroke development and mortality rates in this population.
Article
Oncology
Naoto Seriu, Shinji Tsukamoto, Yukako Ishida, Nobuki Yamanaka, Tomoo Mano, Yasuyo Kobayashi, Marina Sajiki-Ito, Yusuke Inagaki, Yuu Tanaka, Masayuki Sho, Akira Kido
Summary: This study investigated the impact of comorbidities on the execution and therapeutic effects of rehabilitation. The results showed that comorbidities were not associated with the duration of rehabilitation or length of hospital stay, but were associated with the severity of surgical complications.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Obstetrics & Gynecology
Valeria Stella Vanni, Antonio Quartucci, Agnese Rebecchi, Laura Privitera, Alessia Limena, Eugenio Ventimiglia, Paola Vigano, Massimo Candiani, Andrea Salonia, Enrico Papaleo
Summary: This study evaluated the correlation between clinical and hormonal parameters and comorbidity burden in Caucasian women seeking fertility treatment. The results showed that younger age and lower AMH concentrations are significant independent indicators of decreased general health in women requiring clinical evaluation for fertility treatment.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Surgery
Andrea Lisotti, Romano Linguerri, Igor Bacchilega, Anna Cominardi, Gianmarco Marocchi, Pietro Fusaroli
Summary: The study aimed to evaluate predictive factors for mortality in high-risk surgical patients who underwent EUS-GBD for AC. Severe comorbidities and AKI were independent predictive factors confirming long-term mortality after EUS-GBD. Outcomes of EUS-GBD appear more influenced by patients' conditions rather than by procedure success.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Public, Environmental & Occupational Health
Wenzhe Cao, Shaohua Liu, Shasha Wang, Shengshu Wang, Yang Song, Yao He
Summary: The strategy of ESD with no subsequent additional treatment may be a suitable option for elderly patients at high risk of EGAC, especially for those with a CCI score of 2 or greater.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Oncology
Ju Wu, Simiao Tian, Jian Xu, Nan Cheng, Xi Chen, Jiajun Yin, Zhequn Nie
Summary: This retrospective study involving 376 Chinese gastric cancer patients found that high-risk comorbidities were significantly associated with a higher mortality risk, particularly in male patients. The age-adjusted Charlson Comorbidity Index score was identified as an independent prognostic factor for long-term mortality.
Editorial Material
Urology & Nephrology
Jaime Poncel, Aref S. Sayegh, Oliver Ko, Rene Sotelo
Summary: Hartmann's procedure is a surgical technique used to remove part of the colon and create a colostomy. However, reversing the procedure can lead to complications, such as fistulae formation. In this case, a robotic-assisted repair was performed to fix a complex fistula that occurred as a result of Hartmann's reversal.
INTERNATIONAL BRAZ J UROL
(2023)