Article
Biotechnology & Applied Microbiology
Fatemeh Abedi, Soodabeh Davaran, Malak Hekmati, Abolfazl Akbarzadeh, Behzad Baradaran, Sevil Vaghefi Moghaddam
Summary: The proposed combination therapy using smart responsive nanogels can achieve a synergistic effect for cancer treatment, reduce drug dosage, and improve efficacy.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Chemistry, Physical
Shuo Chen, Shuai Yuan, Qing Bian, Bo Wu
Summary: This study presents a novel spiropyran-based organic-inorganic composite nanogel (NG) prepared through emulsion polymerization using upconverting nanoparticles, spiropyran, acrylic acid, and N,N′-bis(acryloyl)cystamine (BAC) compounds. The crosslinked multi-stimulus responsive nanogels can adjust the release rate by altering various parameters, making it suitable for controlling drug release in complex biological environments. The composite NGs demonstrated highly-efficient and controllable release performance for loaded drugs, providing a wide range of options for novel stimulus-responsive nanocarriers.
Article
Chemistry, Physical
Adrian Ges Naranjo, Herlys Viltres Cobas, Nishesh Kumar Gupta, Katy Rodriguez Lopez, Aldo Martinez Pena, Daniel Sacasas, Ruben Alvarez Brito
Summary: Nanogels offer a promising approach for enhancing cancer therapy by increasing the concentration of anti-tumor agents at tumor sites and prolonging their effects on cancer cells without significantly impacting normal tissues.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biophysics
Xinjing Du, Yuanyuan Peng, Chunyue Zhao, Jinfeng Xing
Summary: This study developed a simple and effective strategy to prepare carmofur-loaded nanogels based on temperature/pH-sensitive monomers using one-pot laser-induced emulsion polymerization. These nanogels exhibited suitable size, great biocompatibility, and sensitivity to specific stimulation, and showed dual-stimuli responsive drug release properties.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Yudian Qiu, Jie Bai, Yecheng Feng, Xiaojing Shi, Xubo Zhao
Summary: This study introduces a synergistic therapy approach for cancer treatment by incorporating catechol moieties, a disulfide cross-linked structure, and pendent carboxyl into polymeric nanogels. The nanogels enable the co-delivery of doxorubicin and bortezomib, with stable interactions at neutral pH but disintegration in acidic environments. In vitro and in vivo studies demonstrate the dual-drug loaded nanogels' ability to effectively suppress tumor growth.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Pharmacology & Pharmacy
Xican Zhang, Pan Zhou, Shijie Zhuo, Feng Zhang, Junyu Yu, Xiaowen Liu
Summary: Therapeutic proteins can be engineered into biocompatible formulations for efficient encapsulation and programmable release using a pH-responsive nanogel, offering new insights for potential medical applications, particularly in cancer treatment.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Multidisciplinary
Mingxin Wang, Somia Yassin Hussain Abdalkarim, Ruixin Gong, Haibin Ji, Zhiming Chen, Yunfei Shen, Ying Zhou, Jiayuan Shen, Hou-Yong Yu
Summary: Polymer composite microspheres with excellent biodegradable and controlled long-term release characteristics have gained significant attention. However, producing polymer microspheres with controlled properties and customizable drug release is still a major challenge. In this study, dual-responsive cellulose nanocrystals were engineered and incorporated into polylactide composite microspheres to achieve controlled and sustained drug release behavior. The results demonstrated a temperature and pH dual-responsive controlled drug release capability of the composite microspheres, highlighting their potential as multifunctional drug delivery systems for medical applications.
Review
Pharmacology & Pharmacy
Yanhong Liu, Linjiao Chen, Qingyang Shi, Qing Zhao, Hongshuang Ma
Summary: Tumor microenvironment-responsive polypeptide nanogels have excellent biocompatibility and degradability, and can be used for selective delivery of antitumor drugs. These nanogels can release drugs in response to stimuli from tumor tissues or cells, reducing side effects and improving efficacy.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Biochemical Research Methods
Shewaye Lakew Mekuria, Zhijun Ouyang, Cong Song, Joao Rodrigues, Mingwu Shen, Xiangyang Shi
Summary: Nanogels are nanosized superconstructs composed of amphiphilic or hydrophilic polymer networks, with unique physicochemical properties that make them suitable for various biomedical applications, particularly in cancer nanomedicine. Dendrimer-based NGs can be synthesized via different methods and used for drug delivery, gene delivery, photothermal therapy, combination therapy, and biological imaging-guided chemotherapy in cancer treatment. Future perspectives include designing new dendrimer-based NGs for different cancer nanomedicine applications.
BIOCONJUGATE CHEMISTRY
(2022)
Review
Biotechnology & Applied Microbiology
Xinjing Du, Yuting Gao, Qi Kang, Jinfeng Xing
Summary: In recent years, exploration of the tumor microenvironment has led to the development of tumor microenvironment-responsive nanogels as drug carriers, showing great potential in improving the efficacy of chemotherapy. Common preparation techniques include free radical polymerization, covalent cross-linking, and physical self-assembly, with drug loading methods such as physical encapsulation and chemical coupling also being utilized for controlled drug release behavior. Challenges and prospects of nanogels as drug carriers are briefly discussed in this review.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Kummara Madhusudana Rao, Maduru Suneetha, Dachuru Vinay Kumar, Hyeon Jin Kim, Yong Joo Seok, Sung Soo Han
Summary: This study developed Dox-encapsulated nanogels that can release the drug under dual stimuli conditions, showing potential for effective cancer treatment.
Article
Biochemistry & Molecular Biology
Kristyna Kolouchova, Ondrej Groborz, Zulfiya Cernochova, Aneta Skarkova, Jan Brabek, Daniel Rosel, Pavel Svec, Zenon Starcuk, Miroslav Slouf, Martin Hruby
Summary: In this study, polymer tracers for F-19 MRI were modified by introducing a redox-responsive monomer, allowing for changes in physicochemical properties in an oxidative environment. These ROS-responsive polymers have potential applications in theranostic purposes, especially in terms of drug delivery systems sensitive to oxidative environments in tumors or inflamed tissues.
Review
Pharmacology & Pharmacy
Diana Rafael, Maria Merce Roca Melendres, Fernanda Andrade, Sara Montero, Francesc Martinez-Trucharte, Mireia Vilar-Hernandez, Esteban Francisco Duran-Lara, Simo Schwartz, Ibane Abasolo
Summary: Despite extensive efforts from the scientific community, advanced cancer remains incurable. However, thermo-responsive hydrogels have shown promise in improving the efficacy of anticancer drugs and reducing adverse effects, leading to advancements in cancer treatment.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Review
Nanoscience & Nanotechnology
Nelli Morgulchik, Nazila Kamaly
Summary: Nanogels are a type of drug delivery system composed of cross-linked polymer networks with different characteristics and functionalities for the delivery of small molecule and macromolecular therapeutics. The stimuli-responsive cross-linkers in nanogels enable controlled release at target sites to improve therapeutic efficiency. Small molecule drugs conjugated to nanogels demonstrate diminished burst release, leading to more predictable release profiles.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Yuhang Huang, Shangyu Li, Logan W. C. Zettle, Yingshan Ma, Hani E. E. Naguib, Eugenia Kumacheva
Summary: Chronic wounds show high levels of cell-free deoxyribonucleic acid (cfDNA), leading to prolonged inflammation and non-healing wounds. Nanogels derived from chitosan and poly{2-[(acryloyloxy)ethyl]trimethylammonium chloride} were found to scavenge cfDNA efficiently due to their positive charge and network structure. The enhanced cfDNA scavenging ability and biocompatibility of the nanogels make them a promising component for chronic wound dressings.
Article
Materials Science, Multidisciplinary
Jalababu Ramani, Madhusudhan Alle, Garima Sharma, K. V. N. Suresh Reddy, Yeongmin Park, K. S. V. Krishna Rao, Jin-Chul Kim
Summary: In this study, pH-responsive hydrogels (GNAHs) based on modified natural polymers were formulated and used for controlled release of the anticancer drug Imatinib mesylate (IMS). The GNAH hydrogels demonstrated porous and canal structures with IMS molecules entrapped within the pores, resulting in excellent controlled-release pattern for more than 48 hours. These findings suggest that GNAH hydrogels could be a potential pH-responsive anticancer drug delivery system for other drugs as well.
Article
Chemistry, Physical
Kasula Nagaraja, Kummara Madhusudana Rao, K. S. V. Krishna Rao, Sung Soo Han
Summary: In this study, pH and temperature-sensitive tamarind gum-based hydrogels were synthesized and loaded with 5-fluorouracil as a model drug. The hydrogels showed dual responsive nature and exhibited remarkable toxicity and cell cycle ability against cancer cells.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Maduru Suneetha, Kummara Madhusudana Rao, Sung Soo Han
Summary: This study develops multifunctional hydrogel wound dressings with cell/tissue adhesive, hemostasis, self-healing, and antibacterial properties. The hydrogel exhibits good mechanical properties and enhances cell proliferation, attachment, and spreading. It also shows rapid blood coagulation and antibacterial effects against Escherichia coli and Staphylococcus aureus.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Pharmacology & Pharmacy
Kummara Madhusudana Rao, Maduru Suneetha, Dachuru Vinay Kumar, Hyeon Jin Kim, Yong Joo Seok, Sung Soo Han
Summary: This study developed Dox-encapsulated nanogels that can release the drug under dual stimuli conditions, showing potential for effective cancer treatment.
Article
Pharmacology & Pharmacy
Kummara Madhusudana Rao, Kannan Badri Narayanan, Uluvangada Thammaiah Uthappa, Pil-Hoon Park, Inho Choi, Sung Soo Han
Summary: In this study, multifunctional fungal mushroom-derived hydrogels were developed for wound dressing applications, with tissue adhesive, hemostasis, self-healing, and antibacterial properties. The hydrogels exhibited good swelling ratio, biodegradability, mechanical properties, and high adhesion strength to porcine skin. Additionally, they showed excellent antibacterial properties and promoted cell viability and attachment, making them a promising material for wound healing.
Article
Chemistry, Multidisciplinary
Kasula Nagaraja, Kummara Madhusudana Rao, Duddekunta Hemalatha, Sunmi Zo, Sung Soo Han, K. S. V. Krishna Rao
Summary: In this study, hydrogels based on natural Strychnos potatorum L. polysaccharide were successfully fabricated and subsequently used as templates for the green synthesis of silver nanoparticles. The hydrogels exhibited dual responsiveness and antibacterial activity, making them suitable for drug release and cancer treatment applications.
Article
Pharmacology & Pharmacy
Adilakshmi Boddu, Sreekanth Reddy Obireddy, Dahong Zhang, K. S. V. Krishna Rao, Wing-Fu Lai
Summary: This study reports the design and fabrication of carbohydrate-based pH-responsive beads with intrinsic anticancer therapy and multidrug co-delivery capacity for combination cancer therapy. The beads effectively act against cancer cells and show promising performance in mediating combination drug therapy to improve the effectiveness of cancer treatment.
Review
Pharmacology & Pharmacy
Kuncham Sudhakar, Seong Min Ji, Madhusudhana Rao Kummara, Sung Soo Han
Summary: Hyaluronic acid-based nanocomposites have shown great potential in improving wound healing. With its unique biological characteristics, HA can act as a drug, an antibacterial agent, and a growth factor, accelerating the healing process in different phases. Additionally, metal nanoparticles and metal oxide nanoparticles loaded with HA nanocomposite have important antibacterial mechanisms and can be used for wound healing applications.
Article
Pharmacology & Pharmacy
Siva Sankar Sana, Ramakrishna Vadde, Raj Kumar, Sai Kumar Arla, Adinarayana Reddy Somala, K. S. V. Krishna Rao, Vijaya Kumar Naidu Boya, Zhang Zhijun, Kunal Mondal, Narsimha Mamidi
Summary: In this study, green and facile synthesis of zinc oxide nanoparticles (ZnO-NPs) from Grewia flavescens was presented. The ZnO-NPs exhibited antibacterial activity and controlled drug release profile under physiological conditions. The structural and optical characteristics of ZnO-NPs were thoroughly investigated and they were found to have a spherical shape with an average size of 20-30 nm. The ZnO-NPs also showed excellent biocompatibility and antimicrobial activity, making them potential candidates for biomedical applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Polymer Science
Kummara Madhusudana Rao, Uluvangada Thammaiah Uthappa, Hyeon Jin Kim, Sung Soo Han
Summary: This study developed hydrogels for tissue adhesion that are biocompatible, antioxidant, and antibacterial. Tannic acid (TA) and fungal-derived carboxymethyl chitosan (FCMCS) were incorporated in a polyacrylamide (PAM) network using free-radical polymerization. The concentration of TA greatly influenced the physicochemical and biological properties of the hydrogels. The hydrogels showed excellent adhesive properties, biocompatibility with skin fibroblast cells, and enhanced antibacterial properties against both Gram-positive and Gram-negative bacteria.
Article
Polymer Science
Kummara Madhusudana Rao, Hyeon Jin Kim, Soyeon Won, Soon Mo Choi, Sung Soo Han
Summary: Cell-cultured meat, made from in vitro cultivation of animal-derived cells, has gained attention as a potential protein source for the future. Porous hydrogels, acting as artificial extracellular matrix, were studied for their effects on the growth and adhesion of bovine satellite muscle cells. The edible gelatin-based hydrogels, supplemented with grape seed extract, showed favorable characteristics and supported the growth of muscle cells, indicating their potential use in cell growth for cultured meat.
Article
Polymer Science
Kummara-Madhusudana Rao, Kummari Subba Venkata Krishna Rao, Ramasubba-Reddy Palem, Uluvangada-Thammaiah Uthappa, Chang-Sik Ha, Sung-Soo Han
Summary: This study investigated the gel properties of naturally-occurring palmyra palm kernel (PPK) and its potential use in delivering chemotherapeutic drugs. PPK hydrogels demonstrated excellent swelling behavior due to the presence of polysaccharide and encapsulated 5-fluorouracil (5-FU) with an efficiency of up to 62%. Characterization techniques revealed that the PPK hydrogel matrix contained dispersed 5-FU molecules, and the release patterns showed gradual release over 12 hours. These findings suggest the potential of PPK hydrogels for treating colon cancer.
Article
Materials Science, Ceramics
Hyeon Jin Kim, Kummara Madhusudana Rao, K. S. V. Krishna Rao, Sung Soo Han
Summary: Bioactive hydrogels with enhanced bone-like apatite formation were developed using a calcium-free phosphate approach. The structure and properties of the hydrogels were validated through analysis techniques. The hydrogels exhibited a porous structure with a fibrous topology, promoting cell growth and adhesion. The phosphate functionality within the hydrogels facilitated rapid biomineralization.
CERAMICS INTERNATIONAL
(2023)
Review
Chemistry, Organic
Kummari Subba Venkata Krishna Rao, Kasula Nagaraja, Boddu Adilakshmi, Jangam Lakshmidevi, Guddety Viswanatha Reddy, Sung Soo Han, Kummara Madhusudana Rao
Summary: This article discusses the recent applications of chitosan-based composite materials as heterogeneous catalysts in various industrial relevant chemical transformations. Chitosan has tunable characteristics and has been proven to be effective in catalyst and functional material synthesis. The composite materials based on chitosan show excellent catalytic performance in organic transformations and can be used to prepare magnetic nanocomposite catalysts with easy separation and high reusability. This article is highly informative and important for the design of further chemical transformations.
CURRENT ORGANIC CHEMISTRY
(2022)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
