4.7 Article

Colloidal transport phenomena of milk components during convective droplet drying

Journal

COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 87, Issue 2, Pages 255-266

Publisher

ELSEVIER
DOI: 10.1016/j.colsurfb.2011.05.026

Keywords

Glass filament method; Single droplet drying; Colloidal transport phenomenon; Crust/skin formation; Surface composition; Surface fat

Ask authors/readers for more resources

Material segregation has been reported for industrial spray-dried milk powders, which indicates potential material migration during drying process. The relevant colloidal transport phenomenon and the underlying mechanism are still under debate. This study extended the glass-filament single droplet drying technique to observe not only the drying behaviour but also the dissolution behaviour of the correspondingly dried single particle. At progressively longer drying stage, a solvent droplet (water or ethanol) was attached to the semi-dried milk particle and the interaction between the solvent and the particle was video-recorded. Based on the different dissolution and wetting behaviours observed, material migration during milk drying was studied. Fresh skim milk and fresh whole milk were investigated using water and ethanol as solvents. Fat started to accumulate on the surface as soon as drying was started. At the initial stage of drying, the fat layer remained thin and the solubility of the semi-dried milk particle was much affected by lactose and protein present underneath the fat layer. Fat kept accumulating at the surface as drying progressed and the accumulation was completed by the middle stage of drying. The results from drying of model milk materials (pure sodium caseinate solution and lactose/sodium caseinate mixed solution) supported the colloidal transport phenomena observed for the milk drying. When mixed with lactose, sodium caseinate did not form an apparent solvent-resistant protein shell during drying. The extended technique of glass-filament single droplet approach provides a powerful tool in examining the solubility of individual particle after drying. (C) 2011 Elsevier B.V. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Engineering, Chemical

A reference-component coordinate system approach to model the mass transfer of a droplet with binary volatiles

Kian Siang Lim, Benu Adhikari, Jie Xiao, Xiao Dong Chen, Cordelia Selomulya, Meng Wai Woo

Summary: This study modified a theoretical framework based on reference-component centered coordinates to enable the prediction of simultaneous absorption and evaporation of droplets consisting of two volatiles. Experimental validation showed that the model reasonably predicted the mass profiles for droplet evaporation but over-predicted in the case of simultaneous absorption and evaporation of droplet.

DRYING TECHNOLOGY (2023)

Article Engineering, Chemical

Synthesis of hierarchical ZSM-5 microspheres with superior performance for catalytic methanol-to-olefin conversion

Yali Zhang, Kai Zhang, Chao Shang, Xiaoning Wang, Lei Wu, Guoqing Huang, Hao Wang, Qiming Sun, Xiao Dong Chen, Zhangxiong Wu

Summary: In this study, uniform and hierarchically macro/mesoporous ZSM-5 microspheres were successfully synthesized using a facile and green strategy combining spray-freeze drying and steaming-assisted crystallization. The hierarchical ZSM-5 catalyst exhibited superior catalytic performance in the methanol-to-olefin conversion reaction, with a prolonged lifetime and improved selectivity to ethylene and propylene compared to conventional microporous ZSM-5 and nano-sized ZSM-5.

AICHE JOURNAL (2023)

Article Chemistry, Applied

A dual-labeled fluorescent probe for visualization of dextranase activity in a simulated food digestion system

Rongjuan Sun, Weiji Liu, Timothy V. Kirk, Xiao Dong Chen

Summary: This study aims to investigate the feasibility of using fluorescent probes for bioimaging of enzyme activity in food digestion. The results show that a dual-labeled fluorescent probe can be used to quantitatively measure dextranase activity, and a linear relationship is obtained between the ratio of fluorescence signals and dextranase concentration ratio.

FOOD CHEMISTRY (2023)

Article Biochemistry & Molecular Biology

Fabrication, Evaluation, and Antioxidant Properties of Carrier-Free Curcumin Nanoparticles

Jinwei Wu, Jiaxin Chen, Zizhan Wei, Pingchuan Zhu, Bangda Li, Qing Qing, Huimin Chen, Weiying Lin, Jianyan Lin, Xuehui Hong, Fei Yu, Xiaodong Chen

Summary: Carrier-free curcumin nanoparticles (CFC NPs) were prepared by adding the DMSO solution of Cur into DI water under continuous rapid stirring. The CFC NPs exhibited a spherical shape with a diameter of 65.25 +/- 2.09 nm (PDI = 0.229 +/- 0.107) and a high loading capacity (LC) of 96.68 +/- 0.03%. Furthermore, the CFC NPs significantly improved the water dispersibility and release of Cur in vitro, and showed significantly enhanced DPPH radical scavenging activity. These results suggest that CFC NPs could be a promising vehicle for widening the applications of Cur in the food industry.

MOLECULES (2023)

Article Engineering, Chemical

Spray freeze dried niclosamide nanocrystals embedded dry powder for high dose pulmonary delivery

Shengyu Zhang, Shen Yan, Kangwei Lu, Shixuan Qiu, Xiao Dong Chen, Winston Duo Wu

Summary: Based on drug repositioning strategy, niclosamide has shown potential for treating COVID-19. However, developing effective NCL delivery formulations remains challenging. In this study, NCL-embedded dry powder for inhalation was fabricated using a novel spray freeze drying technology. By adjusting the composition and temperature, the size, morphology, crystal properties, flowability, and aerosol performance of the SFD microparticles were systematically investigated.

POWDER TECHNOLOGY (2023)

Article Engineering, Chemical

Neural network modeling of the dynamic inactivation of probiotics during single droplet drying for improved cell viability

Hong Zhu, Dongbiao Jin, Nan Fu, Xiao Dong Chen, Jie Xiao

Summary: A multi-task convolutional self-attention network (CSAN) has been developed for dynamic modeling of probiotics inactivation during single droplet drying (SDD). The model effectively learns from historical data and predicts inactivation dynamics throughout the whole drying process, outperforming many existing models in terms of prediction accuracy. By using this model, two optimal SDD conditions have been identified with high terminal solid contents (>90 wt%) and cell survival ratios (>0.65).

POWDER TECHNOLOGY (2023)

Article Biochemistry & Molecular Biology

Intestinal absorption of DHA microcapsules with different formulations based on ex vivo rat intestine and in vitro dialysis models

Zejun Hu, Peng Wu, Yiqing Chen, Luping Wang, Xia Jin, Xiao Dong Chen

Summary: In this study, an ex vivo absorption model based on the permeability of the rat small intestine was established to evaluate the intestinal absorption of DHA microcapsules with five formulations after gastrointestinal digestion. The results showed that the permeability of glucose solution increased with concentration, while the absorption rate of DHA microcapsules was low. The absorption rate was also influenced by the release of free fatty acids from the microcapsules.

FOOD & FUNCTION (2023)

Article Engineering, Chemical

New understanding from intestinal absorption model: How physiological features influence mass transfer and absorption

Yifan Qin, Xiao Dong Chen, Aibing Yu, Jie Xiao

Summary: Mathematical modeling of mass transfer and absorption in the small intestine is challenging and requires a reliable and computationally efficient predictive model. This study derives an absorption model that considers the 3D intestinal inner wall structure and can be used in a 1D distributed model. Computational fluid dynamics simulations are used to quantify the mass-transfer coefficient. The model provides insights into the influence of intestinal morphology and motility on mass transfer and absorption.

AICHE JOURNAL (2023)

Article Engineering, Chemical

Viscous flow through a thin-walled elastic hollow ellipsoid-Experiments to demonstrate a potential flowmeter

Xiaoqing Zhu, Yu Zhang, Xiao Dong Chen

Summary: The large deformation of an elastic hollow ellipsoid was investigated as a flowmeter mechanism. Relationships were found between pressure drop, deformation, flowrate, and fluid viscosity. The experiment used a silicone hollow ellipsoid with dimensions of 0.05 m (long axis), 0.03 m (short axis), and a wall thickness of 3.5 x 10(-4) +/- 4.6 x 10(-5) m. A monotonic relationship was observed between flowrate and the ellipsoid's representative diameter. The effect of viscosity on flowrate was inconclusive, but the sensitivity of the ellipsoid's expansion to spatial variations in wall thickness was noted.

ASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING (2023)

Article Chemistry, Applied

Impact of casein-to-whey protein ratio on gastric emptying, proteolysis, and peptidome profile of fermented milk during in vitro dynamic gastrointestinal digestion in preschool children

Hongyan Zhang, Sufang Duan, Yang Yu, Ren'an Wu, Jingjing Wang, Xiao Dong Chen, Ignatius Man-Yau Szeto, Peng Wu, Yan Jin

Summary: The effects of casein-to-whey ratios in fermented milk on gastric emptying, proteolysis and intestinal peptidome were investigated using an in vitro dynamic stomach-intestine system mimicking pre-school children digestion. The research found that the gastric emptying rate varied insignificantly among the milk samples. After 120 min digestion, the highest extent of proteolysis was observed at a casein-to-whey ratio of 2:1 due to the fewest gastric protein aggregates and relatively abundant caseins. Intestinal peptides derived from caseins or whey proteins showed a positive correlation with their parent protein content. The most abundant bioactive whey peptides were found at a casein-to-whey ratio of 1:1.5 after intestinal digestion. These findings demonstrated the importance of protein compositions in fermented milk on gastrointestinal proteolysis and peptide release in vitro, which is meaningful for future development of milk products that are more suitable for children.

FOOD CHEMISTRY (2023)

Article Engineering, Chemical

Preparation of curcumin-loaded MPEG-PTMC nanoparticles: Physicochemical properties, antioxidant activity, and in vivo pharmacokinetic behavior

Fei Yu, Zizhan Wei, Jiaxin Chen, Yufei Long, Qing Qing, Bangda Li, Xinyue Zhang, Huimin Chen, Tianshu Lan, Pingchuan Zhu, Peihong Shen, Wei Zeng, Jianyan Lin, Zhongquan Qi, Xuehui Hong, Xiao Dong Chen

Summary: In this study, MPEG-PTMC@Cur NPs were prepared using MPEG-PTMC as the carrier, which showed improved physicochemical stability and photochemical stability of Cur. The NPs also exhibited enhanced antioxidant activity and oral bioavailability. Therefore, MPEG-PTMC@Cur NPs could be a promising delivery system for Cur.

POWDER TECHNOLOGY (2023)

Article Engineering, Chemical

Making a Soft Elastic Pulsation Pump (SEPP)

Hao Gu, Yun Xia, Yu Zhang, Xiao Dong Chen

Summary: In this study, a soft-elastic pulsation pump (SEPP) made of silicone rubber was developed and examined. The SEPP was driven by an external squeezing mechanism and featured a silicone one-way valve to prevent backflow. The material characteristics, durability, and performance of the SEPP were evaluated, and it was found to have good protection on blood. The technical details and experimental results provided a solid foundation for developing higher capacity SEPPs, which could potentially be applied as effective ventricular assist devices.

PROCESSES (2023)

Article Food Science & Technology

Real-time spatial quantification of gastric acid diffusion in whey protein gels with different NaCl concentrations by wide-field fluorescence microscopy

Xue Dong, Haoyu Zhuo, Ke Wang, Peng Wu, Xiao Dong Chen

Summary: This study quantified the diffusion and spatial distribution of gastric acids in whey protein isolate (WPI) gels during simulated digestion. It was found that regardless of NaCl concentration, the outer surface of the gels quickly formed a near-saturated layer with a higher acid concentration compared to the inner layer. The pH decrease was more significant in gels with higher NaCl concentration due to a looser network structure that facilitated acid diffusion.

FOOD RESEARCH INTERNATIONAL (2023)

Article Engineering, Chemical

Soymilk modification by immobilized bacteria in a soft elastic tubular reactor's wall

Saartje Hernalsteens, Hai Hua Cong, Xiao Dong Chen

Summary: We developed an immobilized mixed strains system on agitated flasks and a soft elastic tubular reactor (SETR) to obtain a whole soymilk fermented product. The mix of Lactobacillus plantarum/Bacillus subtilis subsp. Natto, immobilized in gellan/xanthan/PU foam mat lining the reactor, resulted in a product with improved nutrition and reduced waste accumulation. This immobilization and SETR mixing method can be explored as a bioprocess option for non-traditional media.

JOURNAL OF FOOD ENGINEERING (2023)

Article Engineering, Environmental

Postsynthesis of β-FeOOH/SBA-15 composites via mild ozone treatment: Effective surfactant removal and perfect property preservation for enhanced arsenic adsorption

Guoqing Huang, Dongling Mao, Yali Zhang, Xiao Dong Chen, Zhangxiong Wu

Summary: This work investigated the use of ozone treatment for the postsynthesis of Fe-containing SBA-15 materials, where the surfactant was almost completely removed while maintaining other properties. The ozone treatment could effectively remove the triblock copolymer P123, while preserving the hydroxyl groups of SBA-15 and the dispersion state of Fe. The ozone-treated samples exhibited enhanced arsenic adsorption performance.

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2023)

Article Biophysics

Functional surfaces for exosomes capturing and exosomal microRNAs analysis

Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli

Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Fucoidan-mediated targeted delivery of dasatinib-loaded nanoparticles amplifies apoptosis and endows cytotoxic potential in triple-negative breast cancer

Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh

Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Graphene oxide-doped chiral dextro-hydrogel promotes peripheral nerve repair through M2 polarization of macrophages

Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng

Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Analysis of surfactant production by Bacillus cereus GX7 and optimization of fermentation conditions

Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue

Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

A 3D physical model predicting favorable bacteria adhesion

Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina

Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

UV-C driven reduction of nanographene oxide opens path for new applications in phototherapy

Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto

Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Impact of the physical properties of contact lens materials on the discomfort: role of the coefficient of friction

D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione

Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Structural rearrangement of elastin under oxidative stress

Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta

Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

A dual-functional strontium-decorated titanium implants that guides the immune response for osseointegration of osteoporotic rats

Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang

Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Colloidal crystals array enabled bionic biliary stent for efficient domestic biofluid management

Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu

Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Biomaterials coated with zwitterionic polymer brush demonstrated significant resistance to bacterial adhesion and biofilm formation in comparison to brush coatings incorporated with antibiotics

Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi

Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Croconaine conjugated cationic polymeric nanoparticles for NIR enhanced bacterial killing

Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li

Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

A repertoire of nanoengineered short peptide-based hydrogels and their applications in biotechnology

Ipsita Sahu, Priyadarshi Chakraborty

Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Conductive 3D Ti3C2Tx MXene-Matrigel hydrogels promote proliferation and neuronal differentiation of neural stem cells

Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian

Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)

Article Biophysics

Effect of the oxygenic groups on activated carbon on its hemocompatibility

Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong

Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.

COLLOIDS AND SURFACES B-BIOINTERFACES (2024)