Article
Polymer Science
Fanny Coumes, Gaelle Le Fer, Aurelie Malfait, Richard Hoogenboom, David Fournier, Patrice Woisel
Summary: A well-defined copolymer bearing supramolecular recognition units was designed for the development of multi-responsive polymer materials, showing high association constant with the electron-deficient CBPQT(4+), 4Cl(-) host. The addition of host to the copolymer resulted in the formation of donor-acceptor inclusion complexes, with the purple solution intensity proportional to the amount of host added. The thermoresponsive behavior of the copolymer was highlighted, showing a direct relationship between cloud point temperature and the amount of host added, programmable within a specific temperature window by adjusting pH.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Chemistry, Applied
Marco A. De Jesus-Tellez, Susana De la Rosa-Garcia, Itzel Medrano-Galindo, Ingrid Rosales-Penafiel, Sergio Gomez-Cornelio, Carlos Guerrero-Sanchez, Ulrich S. Schubert, Patricia Quintana-Owen
Summary: In this study, a series of PDMAEMAs with different molar masses were synthesized by RAFT polymerization and treated with two alkyl halides to assess their antifungal activity against various fungi. The results demonstrated that PDMAEMAs, especially those with low molar mass, exhibited significant antifungal properties, with DQ having less impact than molar mass on antifungal activity. This detailed screening contributes to a better understanding of PDMAEMA-based composites for antimicrobial protective coatings.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Materials Science, Multidisciplinary
Puja Das Karmakar, Aniruddha Pal, Subhadip Bodhak, Sagar Pal
Summary: The study synthesized nanocomposites consisting of magneto-responsive gamma-Fe2O3 NPs and copolymers, with a regular core-shell morphology where the magnetic NPs act as the core and the copolymer as the shell. This developed nanocarrier has been found to be highly efficient in carrying a hydrophobic drug (naproxen).
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Polymer Science
Valdomiro V. de Souza, Gustavo P. B. Carretero, Phelipe A. M. Vitale, Iris Todeschini, Paloma O. Kotani, Greice K. Saraiva, Cristiane R. Guzzo, Hernan Chaimovich, Fabio H. Florenzano, Iolanda M. Cuccovia
Summary: Amphiphilic diblock copolymers can assemble in aqueous solutions to form polymersomes, which can respond to pH, temperature, and other conditions. These robust vesicles are being studied as drug delivery systems or nanoreactors. Through characterization, it was found that these polymersomes with dual stimulus-response may serve as a platform for gene delivery and nanoreactors.
Article
Chemistry, Multidisciplinary
Satu Hakkinen, Joji Tanaka, Ramon Garcia Maset, Stephen C. L. Hall, Steven Huband, Julia Y. Rho, Qiao Song, Sebastien Perrier
Summary: This study reports the polymerisation-induced self-assembly of copolymers during RAFT grafting, showing the formation of various morphologies of micelles in the polymerisation process, providing new avenues for controlling polymer structure and material properties.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Chen Wang, Jie Zhang, Hanying Zhao
Summary: Surfactant-free reversible addition-fragmentation transfer (RAFT)-mediated emulsion polymerization has been used to synthesize latex particles. In this study, RAFT emulsion polymerization of methyl methacrylate (MMA) mediated by protonated poly(2-(dimethylamino)ethyl methacrylate) (H+-PDMAEMA) macromolecular chain transfer agent (macro-CTA) was investigated. The nucleation time and rate of emulsion polymerization were found to be dependent on the chain length of H+-PDMAEMA-CTA and the molar ratio of free radical initiator/macro-CTA. The size and size distribution of the latex particles could be controlled by adjusting the macro-CTA chain length and MMA/macro-CTA molar ratio.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Polymer Science
Shehla Mushtaq, Nasir M. Ahmad, Azhar Mahmood, Mudassir Iqbal
Summary: Amphiphilic copolymers of P(DMAEMA-co-MMA) with antibacterial activity were synthesized and optimized to control biofilm adhesion, exhibiting significant zones of inhibition against Gram-positive Staphylococcus aureus and Gram-negative Escherchia coli. The copolymer PDM1 showed good inhibitory effects, particularly in controlling bacterial biofilm adhesion.
Article
Biochemistry & Molecular Biology
Xiaohong Liu, Hui Yin, Xia Song, Zhongxing Zhang, Jun Li
Summary: The study focuses on grafting lignin to develop nonviral gene delivery carriers. A series of lignin-PDMAEMA graft copolymers were synthesized and the effect of grafting degree and cationic chain length on gene transfection efficiency was investigated.
Article
Chemistry, Physical
Ameneh Taghavi-Kahagh, Seyedeh-Arefeh Safavi-Mirmahalleh, Reza Pashaei-Sarnaghi, Mehdi Salami-Kalajahi, Hossein Roghani-Mamaqani
Summary: Polyampholyte star copolymers were synthesized through a two-step RAFT polymerization and DPP polymerization, and their morphological changes and drug release behavior under different pH conditions were studied.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Polymer Science
Thao Phuong Le Nguyen, Thao Thanh Bui, Cam Hong Thi Nguyen, Duong Thanh Le, Tam Huu Nguyen, Le-Thu T. Nguyen, Quoc-Thiet Nguyen, Mai Ha Hoang, Tsutomu Yokozawa, Ha Tran Nguyen
Summary: In this research, diblock copolymers consisting of regioregular poly(3-hexylthiophene) (P3HT) and poly(2-(dimethylamino)ethyl methacrylate-random-1-pyrenylmethyl methacrylate) (P(DMAEMA-r-PyMA)) were successfully synthesized using Grignard metathesis (GRIM) method and atom transfer radical polymerization reaction (ATRP). The copolymer exhibited well-defined structure with average molecular weight of 11300 g/mol and low polydispersity below 1.5. The structure of the polymer was characterized using gel permeation chromatography (GPC), Fourier transform infrared (FTIR) spectroscopy and proton nuclear magnetic resonance (H-1 NMR) spectroscopy. Additionally, the optical and thermal properties of the polymers were analyzed using ultraviolet-visible (UV-Vis), differential scanning calorimetry (DSC) spectroscopy and fluorescence spectroscopy. Interestingly, P3HT-b-P(DMAEMA-r-PyMA) was found to have potential as a chemosensor for trace detection of trinitrotoluene (TNT) explosive.
JOURNAL OF POLYMER RESEARCH
(2023)
Article
Polymer Science
Dragutin Nedeljkovic
Summary: The synthesis of functional block-copolymer was explored through three different polymerization mechanisms, resulting in lower than desired molecular weight for some compositions. The attempt to synthesize block-copolymers with higher molecular weight was unsuccessful, likely due to unwanted side reactions. It was concluded that the combination of sequential anionic polymerization and atomic transfer radical polymerization was not suitable for this specific system.
Article
Polymer Science
Dmitry V. Orekhov, Alexey P. Sivokhin, Alexander S. Simagin, Oleg A. Kazantsev, Ksenia V. Otopkova, Alexey D. Ovchinnikov, Ilya N. Makhov, Nina B. Melnikova
Summary: Betulin, a natural triterpene, has been modified to increase its solubility in water by incorporating it into an amphiphilic copolymer. Well-defined biocompatible copolymers with high betulin content have been synthesized. These copolymers exhibit thermoresponsive behavior and have potential applications in targeted drug delivery.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Polymer Science
Makoto Obata, Satoshi Masuda, Masaki Takahashi, Kohei Yazaki, Shiho Hirohara
Summary: The study investigated the impact of hydrophobic R groups on various properties of polymeric micelles loaded with ZnPc for photodynamic therapy. The presence of aromatic R groups led to larger micelles with loosely packed ZnPc aggregates, resulting in higher release and enhanced photodynamic effect compared to micelles with aliphatic R groups.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Polymer Science
Daniela de Morais Zanata, Maria Isabel Felisberti
Summary: In this study, thermo-responsive and pH-responsive triblock copolymers were synthesized, which can self-assemble into nanostructures and encapsulate hydrophobic molecules under specific conditions. The P4VP blocks can coordinate with Cu2+ to form a thermo- and pH-responsive nanogel, achieving size reduction through thermo- or pH-induced deswelling.
Article
Nanoscience & Nanotechnology
Sarthik Samanta, Shrabana Sarkar, Nikhil K. Singha
Summary: In this hi-tech world, smart coatings have attracted significant attention from materials scientists due to their versatile applications. The layer-by-layer (LbL) technique is commonly used to produce suitable smart coatings. In this study, a smart coating with healing, antifogging, and fluorescence properties was fabricated using the LbL assembly of an anionic amphiphilic block copolymer latex and cationic inorganic POSS nanoparticles. This finding provides a simple water-based LbL coating with low VOC and multifunctional properties, which can be potential material for various applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
