Inhibition of G Protein-Coupled Receptor 81 (GPR81) Protects Against Ischemic Brain Injury

Optogenetic Countering of Glial Acidosis Suppresses Glial Glutamate Release and Ischemic Brain Damage

(2014) Kaoru Beppu et al.   NEURON

Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

(2013) K. H. Lauritzen et al.   CEREBRAL CORTEX

Intracellular lactate signaling cascade in atrial remodeling of mitral valvular patients with atrial fibrillation

(2013) Jing Xu et al.   Journal of Cardiothoracic Surgery

A Novel Neuroprotective Strategy for Ischemic Stroke: Transient Mild Acidosis Treatment by CO2 Inhalation at Reperfusion

(2013) Yan-Ying Fan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

(2012) Carole Berthet et al.   CEREBROVASCULAR DISEASES

Transient Lack of Glucose but not O2is Involved in Ischemic Postconditioning-Induced Neuroprotection

(2012) Yan-Ying Fan et al.   CNS Neuroscience & Therapeutics

Acidic preconditioning protects against ischemia-induced brain injury

(2012) Chen-hui Zhang et al.   NEUROSCIENCE LETTERS

Monocarboxylate Transporter 2 and Stroke Severity in a Rodent Model of Sleep Apnea

(2011) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial dysfunction as a mediator of hippocampal apoptosis in a model of hepatic encephalopathy

(2011) J. Bustamante et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Protective effects of d-3-hydroxybutyrate and propionate during hypoglycemic coma: Clinical and biochemical insights from infant rats

(2011) Peter W. Schutz et al.   MOLECULAR GENETICS AND METABOLISM

Adipose Tissue Lipolysis Revisited (Again!): Lactate Involvement in Insulin Antilipolytic Action

(2010) Dominique Langin   Cell Metabolism

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Activation of the Central Histaminergic System is Involved in Hypoxia-Induced Stroke Tolerance in Adult Mice

(2010) Yan-Ying Fan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Acid-Sensing Ion Channels in Acidosis-Induced Injury of Human Brain Neurons

(2010) Minghua Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurons and Neuronal Stem Cells Survive in Glucose-Free Lactate and in High Glucose Cell Culture Medium During Normoxia and Anoxia

(2010) Sascha Wohnsland et al.   NEUROCHEMICAL RESEARCH

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

(2009) Kuniyasu Niizuma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroprotective Role of Lactate after Cerebral Ischemia

(2009) Carole Berthet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cell-cell and intracellular lactate shuttles

(2009) George A. Brooks   JOURNAL OF PHYSIOLOGY-LONDON

Role of GPR81 in lactate-mediated reduction of adipose lipolysis

(2008) Tian-Quan Cai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inflammatory Cytokines in Acute Ischemic Stroke

(2008) Antonino Tuttolomondo et al.   CURRENT PHARMACEUTICAL DESIGN

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

(2008) Changlu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE