Blocking LINGO-1 as a Therapy to Promote CNS Repair: From Concept to the Clinic

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Priorities in Parkinson's disease research

(2011) Wassilios G. Meissner et al.   NATURE REVIEWS DRUG DISCOVERY

LINGO-1 negatively regulates TrkB phosphorylation after ocular hypertension

(2010) Qing-Ling Fu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Passive Immunization with LINGO-1 Polyclonal Antiserum Afforded Neuroprotection and Promoted Functional Recovery in a Rat Model of Spinal Cord Injury

(2010) Jun Lv et al.   NEUROIMMUNOMODULATION

Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis

(2010) Ranjan Dutta et al.   PROGRESS IN NEUROBIOLOGY

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

(2009) Sha Mi et al.   ANNALS OF NEUROLOGY

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Combined effect of brain-derived neurotrophic factor and LINGO-1 fusion protein on long-term survival of retinal ganglion cells in chronic glaucoma

(2009) Q.-L. Fu et al.   NEUROSCIENCE

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination

(2009) Yueting Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LINGO-1 antagonists as therapy for multiple sclerosis:in vitroandin vivoevidence

(2008) Richard A Rudick et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

LINGO-1 and its role in CNS repair

(2008) Sha Mi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY