Assessing QT Interval Prolongation and its Associated Risks with Antipsychotics

The safety of atypical antipsychotics: does QTc provide all the answers?

(2011) Jimmi Nielsen   Expert Opinion On Drug Safety

10-Year trends in the treatment and outcomes of patients with first-episode schizophrenia

(2010) J. Nielsen et al.   ACTA PSYCHIATRICA SCANDINAVICA

The effect of sertindole on QTD and TPTE

(2010) J. Nielsen et al.   ACTA PSYCHIATRICA SCANDINAVICA

Safety of sertindole versus risperidone in schizophrenia: principal results of the sertindole cohort prospective study (SCoP)

(2010) S. H. L. Thomas et al.   ACTA PSYCHIATRICA SCANDINAVICA

Antipsychotic-associated all-cause and cardiac mortality: what should we worry about and how should the risk be assessed?

(2010) Christoph U. Correll et al.   ACTA PSYCHIATRICA SCANDINAVICA

Comparative Mortality Associated With Ziprasidone and Olanzapine in Real-World Use Among 18,154 Patients With Schizophrenia: The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC)

(2010) Brian L. Strom et al.   AMERICAN JOURNAL OF PSYCHIATRY

Drug- and non-drug-associated QT interval prolongation

(2010) Charlotte Van Noord et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Covariate Analysis of QTc and T-Wave Morphology: New Possibilities in the Evaluation of Drugs That Affect Cardiac Repolarization

(2010) C Graff et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Antipsychotics Associated with the Development of Type 2 Diabetes in Antipsychotic-Naïve Schizophrenia Patients

(2010) Jimmi Nielsen et al.   NEUROPSYCHOPHARMACOLOGY

Effects of Oral Ziprasidone and Oral Haloperidol on QTc Interval in Patients with Schizophrenia or Schizoaffective Disorder

(2010) Jeffrey J Miceli et al.   PHARMACOTHERAPY

Last episode psychosis

(2009) Povl Munk-Jørgensen et al.   ACTA PSYCHIATRICA SCANDINAVICA

Correction for QT/RR Hysteresis in the Assessment of Drug-Induced QTc Changes-Cardiac Safety of Gadobutrol

(2009) Marek Malik et al.   ANNALS OF NONINVASIVE ELECTROCARDIOLOGY

Drug-induced arrhythmias and sudden cardiac death: implications for the pharmaceutical industry

(2009) Matthew J. Killeen   DRUG DISCOVERY TODAY

Drug-Induced Changes in the T-Wave Morphology

(2009) Marek Malik   DRUG SAFETY

Identifying Drug-Induced Repolarization Abnormalities from Distinct ECG Patterns in Congenital Long QT Syndrome

(2009) Claus Graff et al.   DRUG SAFETY

Thorough QT Studies

(2009) Marek Malik et al.   DRUG SAFETY

The European Post-marketing Observational Sertindole Study: an investigation of the safety of antipsychotic drug treatment

(2009) Siegfried Kasper et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Sertindole causes distinct electrocardiographic T-wave morphology changes

(2009) Jimmi Nielsen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The genetic basis of long QT and short QT syndromes: A mutation update

(2009) Paula L. Hedley et al.   HUMAN MUTATION

Quantitative Analysis of T-wave Morphology Increases Confidence in Drug-Induced Cardiac Repolarization Abnormalities: Evidence From the Investigational IKrInhibitor Lu 35-138

(2009) Claus Graff et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Antipsychotic Polypharmacy and Risk of Death From Natural Causes in Patients With Schizophrenia

(2009) Lone Baandrup et al.   JOURNAL OF CLINICAL PSYCHIATRY

Psychiatrists’ attitude towards and knowledge of clozapine treatment

(2009) J. Nielsen et al.   JOURNAL OF PSYCHOPHARMACOLOGY

11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)

(2009) Jari Tiihonen et al.   LANCET

Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac Death

(2009) Wayne A. Ray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antipsychotic Agents and Sudden Cardiac Death — How Should We Manage the Risk?

(2009) Sebastian Schneeweiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Calcium channel blockers, NOS1AP, and heart-rate-corrected QT prolongation

(2009) Charlotte van Noord et al.   Pharmacogenetics and Genomics

QT and TdP. QT: an unreliable predictor of proarrhythmia

(2008) L. M. Hondeghem   ACTA CARDIOLOGICA

Subject-specific profiles of QT/RR hysteresis

(2008) Marek Malik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Sertindole Safety Survey: A retrospective analysis under a named patient use programme in Europe

(2008) Christophe Lançon et al.   BMC Psychiatry

Drug-induced long QT syndrome and drug development

(2008) J. M. Ritter   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

High-dose and combination antipsychotic prescribing in acute adult wards in the UK: The challenges posed by p.r.n. prescribing

(2008) Carol Paton et al.   BRITISH JOURNAL OF PSYCHIATRY

New descriptors of T-wave morphology are independent of heart rate

(2008) Mads P. Andersen et al.   JOURNAL OF ELECTROCARDIOLOGY

TpeakTend interval in long QT syndrome

(2008) Jorgen K. Kanters et al.   JOURNAL OF ELECTROCARDIOLOGY

Dispersions of repolarization and ventricular arrhythmogenesis: Lessons from animal models

(2008) Matthew J. Killeen et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY