☆ 4.3 Article

Vascular Contribution to Alzheimer Disease: Predictors of Rapid Progression

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2013)

Journal

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS

Volume 12, Issue 4, Pages 532-537

Publisher

BENTHAM SCIENCE PUBL

DOI: 10.2174/1871527311312040015

Keywords

Alzheimer disease; cerebral blood flow; disease progression; hemodynamics; risk factors; transcranial Doppler

Categories

Neurosciences Pharmacology & Pharmacy

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Abstract

Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.

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