Pravastatin to prevent recurrent fetal death in massive perivillous fibrin deposition of the placenta (MPFD)

Pravastatin for the Prevention of Preeclampsia in High-Risk Pregnant Women

(2016) Maged M. Costantine et al.   OBSTETRICS AND GYNECOLOGY

The effect of prenatal pravastatin treatment on altered fetal programming of postnatal growth and metabolic function in a preeclampsia-like murine model

(2014) Mollie McDonnold et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Discordant clinical presentations of preeclampsia and intrauterine fetal growth restriction with similar pro- and anti-angiogenic profiles

(2014) Thushari I. Alahakoon et al.   Journal of Maternal-Fetal & Neonatal Medicine

Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia

(2014) Wenda Ramma et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

2013 ACC/AHA Cholesterol Treatment Guideline

(2014) Seth S. Martin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The pharmacology of statins

(2014) Cesare R. Sirtori   PHARMACOLOGICAL RESEARCH

Maternal Pravastatin Prevents Altered Fetal Brain Development in a Preeclamptic CD-1 Mouse Model

(2014) Alissa R. Carver et al.   PLoS One

Maternal plasma concentrations of angiogenic/antiangiogenic factors in the third trimester of pregnancy to identify the patient at risk for stillbirth at or near term and severe late preeclampsia

(2013) Tinnakorn Chaiworapongsa et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Evidence of an imbalance of angiogenic/antiangiogenic factors in massive perivillous fibrin deposition (maternal floor infarction): a placental lesion associated with recurrent miscarriage and fetal death

(2013) Amy E. Whitten et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Transplacental transfer and distribution of pravastatin

(2013) Tatiana N. Nanovskaya et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Detection of Anti-HLA Antibodies in Maternal Blood in the Second Trimester to Identify Patients at Risk of Antibody-Mediated Maternal Anti-Fetal Rejection and Spontaneous Preterm Delivery

(2013) JoonHo Lee et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Maternal Floor Infarction/Massive Perivillous Fibrin Deposition: A Manifestation of Maternal Antifetal Rejection?

(2013) Roberto Romero et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Long-Term Statin Administration to Dams on High-Fat Diet Protects Not Only Them but Also Their Offspring from Cardiovascular Risk

(2013) M.M. Elahi et al.   ANNALS OF NUTRITION AND METABOLISM

Can changes in angiogenic biomarkers between the first and second trimesters of pregnancy predict development of pre-eclampsia in a low-risk nulliparous patient population?

(2013) L Myatt et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Angiogenic factors combined with clinical risk factors to predict preterm pre-eclampsia in nulliparous women: a predictive test accuracy study

(2013) JE Myers et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Pravastatin Attenuates Hypertension, Oxidative Stress, and Angiogenic Imbalance in Rat Model of Placental Ischemia-Induced Hypertension

(2013) Ashley J. Bauer et al.   HYPERTENSION

Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injury

(2013) Adriana Correa Melo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The effect of maternal pravastatin therapy on adverse sensorimotor outcomes of the offspring in a murine model of preeclampsia

(2013) Alissa R. Carver et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Angiogenic biomarkers for prediction of early preeclampsia onset in high-risk women

(2013) Tiffany A. Moore Simas et al.   Journal of Maternal-Fetal & Neonatal Medicine

The transfer of pravastatin in the dually perfused human placenta

(2013) J. Zarek et al.   PLACENTA

Characterisation of Syncytiotrophoblast Vesicles in Normal Pregnancy and Pre-Eclampsia: Expression of Flt-1 and Endoglin

(2013) Dionne S. Tannetta et al.   PLoS One

Effects of Pravastatin on Angiogenic and Placental Hypoxic Imbalance in a Mouse Model of Preeclampsia

(2013) Antonio F. Saad et al.   Reproductive Sciences

A deficiency in haem oxygenase-1 induces foetal growth restriction by placental vasculature defects

(2012) Ronald J Wong et al.   ACTA PAEDIATRICA

Longitudinal evaluation of predictive value for preeclampsia of circulating angiogenic factors through pregnancy

(2012) Thomas F. McElrath et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Does Immunotherapy for Treatment of Reproductive Failure Enhance Live Births?

(2012) Carolyn B. Coulam et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Late-onset preeclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with maternal underperfusion

(2012) Eleazar Soto et al.   Journal of Maternal-Fetal & Neonatal Medicine

Angiogenic Factors in Maternal Circulation and the Risk of Severe Fetal Growth Restriction

(2011) B. Olav Asvold et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Effects of pravastatin on mediators of vascular function in a mouse model of soluble Fms-like tyrosine kinase-1–induced preeclampsia

(2011) Karin A. Fox et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Maternal HLA Panel-Reactive Antibodies in Early Gestation Positively Correlate with Chronic Chorioamnionitis: Evidence in Support of the Chronic Nature of Maternal Anti-fetal Rejection

(2011) JoonHo Lee et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Maternal Heme Oxygenase 1 Regulates Placental Vasculature Development via Angiogenic Factors in Mice1

(2011) Hui Zhao et al.   BIOLOGY OF REPRODUCTION

Unexplained fetal death has a biological signature of maternal anti-fetal rejection: chronic chorioamnionitis and alloimmune anti-human leucocyte antigen antibodies

(2011) JoonHo Lee et al.   HISTOPATHOLOGY

Statin treatment depresses the fetal defence to acute hypoxia via increasing nitric oxide bioavailability

(2011) Andrew D. Kane et al.   JOURNAL OF PHYSIOLOGY-LONDON

Desensitization in HLA-Incompatible Kidney Recipients and Survival

(2011) Robert A. Montgomery et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Signature of Maternal Anti-Fetal Rejection in Spontaneous Preterm Birth: Chronic Chorioamnionitis, Anti-Human Leukocyte Antigen Antibodies, and C4d

(2011) JoonHo Lee et al.   PLoS One

Intravenous immunoglobulin and idiopathic secondary recurrent miscarriage: a multicentered randomized placebo-controlled trial

(2010) M. D. Stephenson et al.   HUMAN REPRODUCTION

An imbalance between angiogenic and anti-angiogenic factors precedes fetal death in a subset of patients: results of a longitudinal study

(2010) Roberto Romero et al.   Journal of Maternal-Fetal & Neonatal Medicine

Using Pravastatin to Improve the Vascular Reactivity in a Mouse Model of Soluble Fms-Like Tyrosine Kinase-1–Induced Preeclampsia

(2010) Maged M. Costantine et al.   OBSTETRICS AND GYNECOLOGY

Proteases and sFlt-1 Release in the Human Placenta

(2010) S. Zhao et al.   PLACENTA

Soluble fms-Like Tyrosine Kinase 1 (sFlt1), Endoglin and Placental Growth Factor (PlGF) in Preeclampsia among High Risk Pregnancies

(2010) Robert W. Powers et al.   PLoS One

A New Mouse Model to Explore Therapies for Preeclampsia

(2010) Abdulwahab Ahmed et al.   PLoS One

Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

(2010) K. Kumasawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Can the biology of VEGF and haem oxygenases help solve pre-eclampsia?

(2009) Asif Ahmed et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury

(2009) P. Redecha et al.   BLOOD

Villitis of Unknown Etiology Is Associated with a Distinct Pattern of Chemokine Up-Regulation in the Feto-Maternal and Placental Compartments: Implications for Conjoint Maternal Allograft Rejection and Maternal Anti-Fetal Graft-versus-Host Disease

(2009) M. J. Kim et al.   JOURNAL OF IMMUNOLOGY

A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia

(2009) Juan Pedro Kusanovic et al.   Journal of Maternal-Fetal & Neonatal Medicine

A subset of patients destined to develop spontaneous preterm labor has an abnormal angiogenic/anti-angiogenic profile in maternal plasma: Evidence in support of pathophysiologic heterogeneity of preterm labor derived from a longitudinal study

(2009) Tinnakorn Chaiworapongsa et al.   Journal of Maternal-Fetal & Neonatal Medicine

Pravastatin prevents miscarriages in antiphospholipid antibody-treated mice

(2009) Guillermina Girardi   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression

(2009) A. Mak et al.   RHEUMATOLOGY

Statin Treatment in Hypercholesterolemic Pregnant Mice Reduces Cardiovascular Risk Factors in Their Offspring

(2008) Maqsood M. Elahi et al.   HYPERTENSION

The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age

(2008) Offer Erez et al.   Journal of Maternal-Fetal & Neonatal Medicine

The maternal plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated in SGA and the magnitude of the increase relates to Doppler abnormalities in the maternal and fetal circulation

(2008) Tinnakorn Chaiworapongsa et al.   Journal of Maternal-Fetal & Neonatal Medicine

A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate

(2008) Roberto Romero et al.   Journal of Maternal-Fetal & Neonatal Medicine

Recurrent Placental Massive Perivillous Fibrin Deposition Associated with Polymyositis: A Case Report and Review of the Literature

(2008) Mudher Al-Adnani et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Placental Productions and Expressions of Soluble Endoglin, Soluble fms-Like Tyrosine Kinase Receptor-1, and Placental Growth Factor in Normal and Preeclamptic Pregnancies

(2007) Yang Gu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM