Article
Surgery
Sara J. Kuik, Martin van der Heide, Janneke L. M. Bruggink, Arend F. Bos, A. A. Eduard Verhagen, Elisabeth M. W. Kooi, Jan B. F. Hulscher
Summary: Measuring r(int)SO(2), but not r(c)SO(2), seems to be helpful in estimating the survival rate of preterm infants after surgery for NEC. The levels of r(int)SO(2), C-reactive protein, lactate, and fraction of inspired oxygen differed significantly between survivors and non-survivors. Only r(int)SO(2) remained significant in the multiple regression model.
Article
Pediatrics
Willemien S. Kalteren, Arend F. Bos, Klasien A. Bergman, Willem van Oeveren, Jan B. F. Hulscher, Elisabeth M. W. Kooi
Summary: Transfusions of red blood cells (RBC) in preterm infants are associated with oxidative stress and intestinal injury, along with decreased variability in splanchnic oxygenation. This may represent the early pathogenesis of transfusion-associated necrotizing enterocolitis (NEC).
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Elena Palleri, Veronica Frimmel, Urban Flaring, Marco Bartocci, Tomas Wester
Summary: This study aimed to assess the association between hyponatremia and the need for bowel resection and/or NEC-related deaths at the onset of necrotizing enterocolitis (NEC). The findings indicate that hyponatremia and a sudden decrease in plasma sodium at the onset of NEC are associated with an increased risk of severe NEC requiring intestinal surgery or leading to death within 2 weeks.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Shan He, Gang Liu, Xueping Zhu
Summary: This study demonstrates the beneficial effects of human breast milk-derived exosomes in preventing necrotizing enterocolitis by reducing inflammation and injury, and restoring intestinal tight-junction proteins.
PEDIATRIC RESEARCH
(2021)
Article
Pediatrics
E. Palleri, M. van der Heide, J. B. F. Hulscher, M. Bartocci, T. Wester, E. M. W. Kooi
Summary: This study aimed to determine the clinical usefulness of a mean SrSO2 < 30% in predicting necrotizing enterocolitis (NEC) in extremely preterm infants. The study included 86 infants, and found that 70.5% of infants with NEC had a mean SrSO2 < 30%, compared to only 33.3% of those without NEC. The odds of developing NEC were 4.5 times higher in infants with SrSO2 < 30% compared to those with SrSO2 >= 30%.
Article
Pediatrics
Nicolas Vinit, Veronique Rousseau, Aline Broch, Naziha Khen-Dunlop, Taymme Hachem, Olivier Goulet, Sabine Sarnacki, Sylvie Beaudoin
Summary: The Santulli procedure (SP) improves bowel recovery in congenital intestinal malformations, necrotizing enterocolitis (NEC), and bowel perforation. Our study found that 95% of patients achieved anal-stool passing within 9 days after SP, and after a median follow-up of 2.9 years, 90% of patients achieved full oral intake and had normal bowel movement.
Review
Medicine, General & Internal
Siyuan Wu, Sijia Di, Tianjing Liu, Yongyan Shi
Summary: This article provides a detailed review on the early prediction and diagnosis methods of necrotizing enterocolitis (NEC), a life-threatening disease of the digestive system in neonates, including ultrasound, near-infrared spectroscopy, biomarkers, and intestinal microbiota. The aim of this review is to provide a reference for further research and clinical practice.
FRONTIERS IN MEDICINE
(2022)
Article
Pediatrics
Ming Yue, Heying Yang, Mingxia Cui, Yuhang Yuan, Ning Zhang, Xiangyu Zhang, Yan Li
Summary: Santulli enterostomy is a simple and safe surgical procedure that provides early restoration of intestinal continuity without formal laparotomy. Compared to traditional ostomy procedures, Santulli enterostomy has shorter operative time, shorter hospital stay, and lower incidence of postoperative complications.
FRONTIERS IN PEDIATRICS
(2023)
Article
Immunology
Xiao-Lin Yan, Xiao-Chen Liu, Yu-Ni Zhang, Ting-Ting Du, Qing Ai, Xiong Gao, Jing-Li Yang, Lei Bao, Lu-Quan Li
Summary: This study found that succinate plays an important role in the pathogenesis and severity of necrotizing enterocolitis, and the activation of the HIF-1α signaling pathway may lead to disease progression.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Surgery
Akiko Yano, Kazumasa Orihashi, Yukitaka Yoshida, Motone Kuriyama
Summary: Near-infrared spectroscopy can sensitively and accurately reflect the condition of jejunal graft after reconstruction surgery. Postoperative monitoring of rSO(2) value >55% seems to be an adequate criterion for ischemia.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2021)
Article
Obstetrics & Gynecology
Julia Le Bouhellec, Olivier Prodhomme, Thibault Mura, Aurelien Jacquot, Clementine Combes, Lucie Gamon, Sabine Durand, Anne Filleron, Gilles Cambonie
Summary: In premature neonates, near-infrared spectroscopy (NIRS) monitoring was not effective in distinguishing infants with necrotizing enterocolitis (NEC) from those with acute gastrointestinal symptoms.
AMERICAN JOURNAL OF PERINATOLOGY
(2021)
Review
Pediatrics
Ester Maria Gill, Kristine Jung, Niels Qvist, Mark Bremholm Elleb
Summary: There is currently insufficient evidence to support any specific recommendations regarding antibiotic treatment, route of administration, or duration for infants with necrotizing enterocolitis (NEC) at Bell's stage II and III.
Article
Pediatrics
Yasser Elsayed, Mary Seshia
Summary: Clinical management of gut injury remains challenging due to the lack of defined diagnostic criteria. This report introduces an integrated approach using intestinal ultrasound as the primary assessment tool along with other clinical and biochemical markers. This algorithm improves the quality of care, provides more accurate diagnosis of NEC, and differentiates other types of gut injury.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Sofia el Manouni el Hassani, Hendrik J. Niemarkt, Joep P. M. Derikx, Daniel J. C. Berkhout, Andrea E. Ballon, Margot de Graaf, Willem P. de Boode, Veerle Cossey, Christian V. Hulzebos, Anton H. van Kaam, Boris W. Kramer, Richard A. van Lingen, Daniel C. Vijlbrief, Mirjam M. van Weissenbruch, Marc A. Benninga, Nanne K. H. de Boer, Tim G. J. de Meij
Summary: Lower gestational age, early clinical onset, and no maternal corticosteroids administration are predictors for surgical NEC. Low serum bicarbonate in the 3 days prior clinical onset and patent ductus arteriosus for which ibuprofen was administered predict surgical NEC.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Chemistry, Analytical
Mika Ishigaki, Atsushi Ito, Risa Hara, Shun-ichi Miyazaki, Kodai Murayama, Keisuke Yoshikiyo, Tatsuyuki Yamamoto, Yukihiro Ozaki
Summary: This study successfully developed a method of monitoring the increasing number of amide bonds with the elongation of peptide chain length using NIR spectroscopy. By evaluating the dehydration occurring between amino acids and constructing a calibration model with a high determination coefficient, the study provided valuable insights for analyzing amide bonds in the NIR spectra of proteins, polyamino acids, polypeptides, and polyamides.
ANALYTICAL CHEMISTRY
(2021)
Article
Neurosciences
Hui Peng, Augusto Sola, James Moore, Tongchun Wen
JOURNAL OF NEUROSCIENCE RESEARCH
(2010)
Article
Pediatrics
Terri Marin, Cassandra D. Josephson, Niki Kosmetatos, Melinda Higgins, James E. Moore
JOURNAL OF PEDIATRICS
(2014)
Article
Hematology
Terri Marin, James Moore, Niki Kosmetatos, John D. Roback, Paul Weiss, Melinda Higgins, Linda McCauley, Ora L. Strickland, Cassandra D. Josephson
Article
Nursing
Kerry A. Wilder, Susan C. Kuehn, James E. Moore
ADVANCES IN NEONATAL CARE
(2014)
Article
Neurosciences
TC Wen, MR Rogido, JE Moore, T Genetta, H Peng, A Sola
NEUROSCIENCE LETTERS
(2005)
Article
Neurosciences
T. C. Wen, M. Rogido, H. Peng, T. Genetta, J. Moore, A. Sola
