Article
Immunology
Isabelle Desombere, Freya Van Houtte, Ali Farhoudi, Lieven Verhoye, Caroline Buysschaert, Yvonne Gijbels, Sibyl Couvent, Wilfried Swinnen, Hans Van Vlierberghe, Andre Elewaut, Andrea Magri, Zania Stamataki, Philip Meuleman, Jane A. McKeating, Geert Leroux-Roels
Summary: Hepatitis C virus can be transmitted by B cells, but B cells from recently infected patients failed to transmit the virus to mice, while all serum samples were infectious. The study also observed an association between circulating antibodies and B cell transmission of HCV.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Gastroenterology & Hepatology
Norah A. Terrault, Miriam T. Levy, Ka Wang Cheung, Gonzague Jourdain
Summary: The management of viral hepatitis in pregnancy requires special consideration due to the unique characteristics of each hepatitis virus and their impact on maternal and infant outcomes. Preventing mother-to-child transmission is crucial in reducing the global burden of chronic viral hepatitis.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2021)
Article
Health Care Sciences & Services
Rohullah Roien, Sayed Hamid Mousavi, Akihiko Ozaki, Sayed Abulqasem Baqeri, Sayed Mohammad Reza Hosseini, Shoaib Ahmad, Sunil Shrestha
Summary: The study conducted in Kabul, Afghanistan found that healthcare workers have a certain level of knowledge about hepatitis B infection, but the vaccination coverage is low and the awareness of infection control needs to be improved.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2021)
Article
Biophysics
Ru Cheng, Fu Zhu, Min Huang, Qiang Zhang, Hui Hong Yan, Xiao Hui Zhao, Fu Kang Luo, Chun Mei Li, Hui Liu, Gao Lin Liang, Cheng Zhi Huang, Jian Wang
Summary: In this study, a new biosensor named hepatitis virus indicator was developed for the simultaneous detection of HBV and HCV. The biosensor utilized Exo III assisted signal amplification strategy and particle counting technology with a dark-field microscopy, enabling sensitive and selective detection.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Virology
Maisuri T. Chalid, Turyadi, Susan I. Ie, Rizalinda Sjahril, Ridha Wahyuni, M. Nasrum Massi, David H. Muljono
Summary: This study examines the HBV characteristics and potential risk of mother-to-child transmission among HBeAg-negative/HBsAg-positive expectant mothers in an area with a high prevalence of e-CHB. It highlights the importance of considering antiviral prophylaxis eligibility in situations with limited resources and in regions where e-CHB is prevalent, as some HBeAg-negative mothers may still pose a high transmission risk.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Public, Environmental & Occupational Health
Bernada Ndunguru, Diana Wilfred, Anthony Kapesa, Semvua D. Kilonzo, Mariam Mirambo, Fred Hyera, Fabian Massaga
Summary: Despite the availability of hepatitis B vaccines, the uptake among healthcare workers in primary health facilities in Tanzania has not been extensively studied. This lack of information hinders the scaling up of hepatitis B vaccination programs. Therefore, advocacy campaigns and resource mobilization towards promoting vaccination in primary health facilities are crucial.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Ammal M. Metwally, Dalia M. Elmosalami, Hazem Elhariri, Lobna A. El Etreby, Ahmed Aboulghate, Marwa M. El-Sonbaty, Amira Mohsen, Rehan M. Saleh, Ghada A. Abdel-Latif, Sahar Samy, Sherif E. El Deeb, Asmaa M. Fathy, Mohab M. Salah, Mohamed A. Abdel Mawla, Hanaa M. Imam, Nihad A. Ibrahim, Fatma A. Shaaban, Reham Y. Elamir, Mohamed Abdelrahman, Manal H. El-Sayed
Summary: This study aimed to assess the dominance of risk practices associated with HCV endemicity in Egypt and detect the behavioral development level concerning different aspects of HCV risk behaviors with respect to age and gender. The survey revealed that cost-effective strategies could accelerate HCV elimination in Egypt by focusing on motivating the adoption of risk-reduction behaviors, tackling misconceptions, and reinforcing social support.
Article
Gastroenterology & Hepatology
Po-Yao Hsu, Yu-Ju Wei, Po-Cheng Liang, Jia-Jung Lee, Sheng-Wen Niu, Jiun-Chi Huang, Cheng-Ting Hsu, Tyng-Yuan Jang, Ching- Huang, Yi-Hung Lin, Ming-Yen Hsieh, Meng-Hsuan Hsieh, Szu-Chia Chen, Chia-Yen Dai, Zu-Yau Lin, Shinn-Cherng Chen, Jee-Fu Huang, Jer-Ming Chang, Ming-Lun Yeh, Chung-Feng Huang, Yi-Wen Chiu, Shang-Jyh Hwang, Wan-Long Chuang, Ming-Lung Yu
Summary: Hemodialysis patients are at increased risk of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. This study found that hemodialysis patients with HCV exhibited a higher burden of comorbidities, especially in ischemic heart diseases, respiratory disorders, and mental/behavioral disorders, compared to patients with HBV and those without viral hepatitis.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Biology
Emily Martyn, Sarah Eisen, Nicky Longley, Philippa Harris, Julian Surey, James Norman, Michael Brown, Binta Sultan, Tongai G. Maponga, Collins Iwuji, Stuart Flanagan, Indrajit Ghosh, Alistair Story, Philippa C. Matthews
Summary: Hepatitis B virus (HBV) infection is a significant global health threat, causing millions of chronic infections and deaths each year. The impact of HBV disproportionately affects marginalized populations and exacerbates healthcare inequities. The 'inclusion health' agenda seeks to address these disparities and improve HBV diagnosis, treatment, and prevention for excluded populations, contributing to the global goal of eliminating viral hepatitis as a public health threat.
Review
Public, Environmental & Occupational Health
Daniel Atlaw, Biniyam Sahiledengle, Zerihun Tariku
Summary: This study found that the prevalence of HBV and HCV infections among healthcare workers in Africa are 6.81% and 5.58% respectively, indicating a high risk of infection among healthcare workers. Therefore, measures should be taken to reduce the risk of HBV and HCV infections among healthcare workers.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2021)
Article
Biophysics
Suchanat Boonkaew, Abdulhadee Yakoh, Nattaya Chuaypen, Pisit Tangkijvanich, Sirirat Rengpipat, Weena Siangproh, Orawon Chailapakul
Summary: Electrochemical paper-based analytical devices (ePADs) are simple, portable, and low-cost analytical devices for point-of-care testing of clinical biomarkers. A sequential ePAD has been developed for simultaneous detection of hepatitis B surface antigen and hepatitis C core antigen by integrating dual flow behaviors, avoiding the need for complex multi-step reagent manipulation by the user. The proposed ePAD shows high promise as an easy-to-use, portable, and extendable sensor for other multiplex biological assays.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Public, Environmental & Occupational Health
S. Mehmandoost, M. Khezri, G. Mousavian, F. Tavakoli, F. Mehrabi, H. Sharifi, K. Dolan, M. Shokoohi
Summary: This study systematically summarized the prevalence of HIV, HBV, and HCV infections among incarcerated people in Iran. The results showed that the prevalences of these infections are relatively high in this population. Meta-analysis and regression analysis found a decrease in HIV and HCV infections over time.
Editorial Material
Virology
Syeda Kanza Kazmi, Fatima Muhammad Asad Khan, Valentino Natoli, Reem Hunain, Zarmina Islam, Ana Carla dos Santos Costa, Shoaib Ahmad, Mohammad Yasir Essar
Summary: Hepatitis is a significant cause of mortality worldwide, with around 1.34 million deaths annually. Africa is not immune to this issue, with an estimated 100 million individuals infected with Hepatitis B or C. The continent, already fragile, is further burdened by the onset of the COVID-19 pandemic, which could potentially worsen the threat from viral diseases like Hepatitis. Strengthening prevention policies is essential for Africa to build resilience against such threats.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Oncology
Yung-Rung Lai, Ya-Lan Chang, Chiu-Hsiang Lee, Tung-Han Tsai, Kuang-Hua Huang, Chien-Ying Lee
Summary: The study found that patients with HBV and HCV have a higher incidence of NHL, indicating a significant correlation.
Review
Immunology
Wen Hou, Xiaoli Wu
Summary: This study investigates the roles of gamma delta T cells in HBV and HCV infections, discussing the different roles they play in the progression of liver diseases at various stages.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Gastroenterology & Hepatology
Zhou Yuming, Tang Ruqi, Merrill Eric Gershwin, Ma Xiong
CLINICS IN LIVER DISEASE
(2024)
Article
Gastroenterology & Hepatology
Inbal Houri, Gideon M. Hirschfield
CLINICS IN LIVER DISEASE
(2024)
Article
Gastroenterology & Hepatology
Yasameen Muzahim, Ali Wakil, Mehak Bassi, Nikolaos Pyrsopoulos
CLINICS IN LIVER DISEASE
(2024)
Article
Gastroenterology & Hepatology
Brian H. Horwich, Douglas T. Dieterich
CLINICS IN LIVER DISEASE
(2024)
Article
Gastroenterology & Hepatology
Aparna Goel, Paul Kwo
Summary: The goal of autoimmune hepatitis treatment is achieving clinical and biochemical remission. Standard care involves induction treatment with corticosteroids and gradual tapering of steroids. Alternatives to standard therapy can be considered for patients with intolerance or inadequate response. Treatment withdrawal is achievable in less than 20% of patients after 2 years of sustained remission, and liver transplantation should be considered for patients with progressive disease or complications.
CLINICS IN LIVER DISEASE
(2024)
Article
Gastroenterology & Hepatology
Mariana Zapata, Hendrick Pagan-Torres, Marlyn J. Mayo
CLINICS IN LIVER DISEASE
(2024)
Article
Gastroenterology & Hepatology
Aalam Sohal, Sanya Kayani, Kris Kowdley
Summary: Primary sclerosing cholangitis (PSC) is an immune-mediated liver disease characterized by inflammation and fibrosis of bile ducts. It is commonly associated with inflammatory bowel disease, especially ulcerative colitis. The natural history of the disease varies among patients, but most will develop cirrhosis.
CLINICS IN LIVER DISEASE
(2024)