Ocular melanoma: relatively rare but requiring respect

Primary ocular melanoma can involve the uveal tract, conjunctiva, eyelid, or orbit. Uveal melanoma is the most common ocular melanoma and carries a serious prognosis, especially if the tumor is medium or large in size. Conjunctival melanoma manifests on the surface of the eye and has been increasing in incidence. Eyelid and primary orbital melanoma are the least common variants. Early diagnosis from annual ocular examination by an experienced ophthalmologist and treatment strategies are reviewed. (C) 2009 Elsevier Inc. All rights reserved.