Increasing trial efficiency by early reallocation of placebo nonresponders in sequential parallel comparison designs: Application to antidepressant trials

P01-588 - L-methylfolate augmentation of selective serotonin reuptake inhibitors (SSRIS) for major depressive disorder: Results of two randomized, double-blind trials

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Adaptive patient enrichment designs in therapeutic trials

(2009) Sue-Jane Wang et al.   BIOMETRICAL JOURNAL

Early Improvement in the First 2 Weeks as a Predictor of Treatment Outcome in Patients With Major Depressive Disorder

(2009) Armin Szegedi et al.   JOURNAL OF CLINICAL PSYCHIATRY

The State of Innovation in Drug Development

(2008) I Kola   CLINICAL PHARMACOLOGY & THERAPEUTICS

Does early improvement triggered by antidepressants predict response/remission? — Analysis of data from a naturalistic study on a large sample of inpatients with major depression

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Time course of response to antidepressants: Predictive value of early improvement and effect of additional psychotherapy

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