Article
Psychology, Multidisciplinary
Jolana Wagner-Skacel, Nadja Fink, Judith Kahn, Nina Dalkner, Emanuel Jauk, Susanne Bengesser, Marco Mairinger, Gerhard Schuessler, Christoph Pieh, Vanessa Stadlbauer, Alexander H. Kirsch, Sabine Zitta, Alexander R. Rosenkranz, Peter Fickert, Peter Schemmer
Summary: This study aimed to evaluate the impact of a step guided multicomponent interprofessional intervention program on adherence to immunosuppressive medication in kidney or liver transplant recipients. The results showed that the intervention group could compensate higher CV% of Tacrolimus after transplantation in individuals with lower levels of personality functioning and non-adherence.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Cell Biology
Xiaodong Du, Mingqian Li, Chen Huan, Guoyue Lv
Summary: This review discusses the origin, maturation, migration, and pathological effects of dendritic cell subsets in liver transplantation, as well as their roles in transplant rejection and tolerance. The latest progress in dendritic cell-based treatment regimens is also outlined.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Review
Clinical Neurology
Duo-Zi Wang, Bing-Hu Li, Bin-Lu Deng, Fu-Qiang Guo, Shan-Shan Hu, Neng-Wei Yu, Jie Liu
Summary: A woman who underwent solid organ transplantation and received strict immunosuppressive treatment developed anti-CASPR2 encephalitis, which was diagnosed based on positive antibodies in her serum and cerebrospinal fluid. This is the first reported case of anti-CASPR2 encephalitis in post-organ transplantation patients, highlighting the risk of immune-oriented encephalitis in patients undergoing immunosuppression, especially when combined with other immunomodulatory treatments.
NEUROLOGICAL SCIENCES
(2023)
Article
Engineering, Chemical
Guoqing Shi, Jiamin Qi, Guangping Teng, Yanming Wang, Haoyang Shen
Summary: This study investigates the effect and influencing factors of a biological dust suppressant on secondary dust generated by coal dust. The experimental results show that the biological dust suppressant has the best effect on suppressing secondary dust from coal dust with particle size above 200 μm, particularly for lignite.
ADVANCED POWDER TECHNOLOGY
(2022)
Article
Engineering, Chemical
Chunyu Song, Yanyun Zhao, Weimin Cheng, Xiangming Hu, Shucang Zhu, Mingyue Wu, Yijin Fan, Wenhao Liu, Ming Zhang
Summary: This study screened two urease-producing bacteria for coal dust suppression, with results showing their potential in this application. Each bacteria performed best under slightly alkaline and neutral conditions respectively, with SZS1-5 treated coal dust exhibiting stronger resistance to wind and rain.
ADVANCED POWDER TECHNOLOGY
(2021)
Review
Oncology
Wenhui Zhang, Zhikun Liu, Xiao Xu
Summary: Liver transplantation is the most effective treatment for end-stage liver diseases, with significant changes in the immunometabolism microenvironment after transplantation. Immune cells play a crucial role in this environment and studying their complex pathobiology is critical to prevent post-transplant complications. The interplay between cellular metabolism and immune function is evident, with potential for shaping immune responses through targeting different metabolic pathways.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Article
Engineering, Chemical
Yansong Zhang, Guangan Wu, Li Cai, Jie Zhang, Xiangrui Wei, Xiang Wang
Summary: The superfine NaHCO3-shell powder (S-S) composite explosion suppressant prepared by one-step method with an airflow crusher showed excellent explosion suppression performance in optimizing the composition, reducing particle agglomeration, improving dispersion, lowering ignition sensitivity, delaying explosion occurrence time, etc. The suppression effect on coal dust explosion is far better than that of pure NaHCO3 or shell powder.
Article
Food Science & Technology
Lenycia de Cassya Lopes Neri, Monica Guglielmetti, Valentina De Giorgis, Ludovica Pasca, Martina Paola Zanaboni, Claudia Trentani, Elena Ballante, Serena Grumi, Cinzia Ferraris, Anna Tagliabue, KDTs Delphi Validation Study Grp
Summary: This study adapted and validated the Brazilian adherence questionnaire iKetoCheck into the Italian version for evaluating the adherence to ketogenic dietary therapies in Italian drug-resistant epilepsy or GLUT1 deficiency patients. The iKetoCheck is a valid tool consisting of 10 questions that assess various aspects of adherence. It can provide valuable information to improve patient management and optimize the effectiveness of ketogenic dietary therapies.
Article
Immunology
Yi Shan, Debin Qi, Lei Zhang, Lixue Wu, Wenfang Li, Hao Liu, Tao Li, Zhiren Fu, Haili Bao, Shaohua Song
Summary: In this study, the expression and distribution of immune cells in donor organs before and after liver transplantation were explored using single-cell RNA sequencing and T cell receptor (TCR) / B cell receptor (BCR) repertoire sequencing. Functional properties of monocytes/Kupffer cells, T cells, and B cells in grafts were investigated, and shifts in TCR/BCR repertoire after transplantation were observed. This study provides novel strategies for monitoring recipient immune function and treating rejection after liver transplantation.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Ludovico Abenavoli, Giuseppe Guido Maria Scarlata, Maria Rosaria Paravati, Luigi Boccuto, Francesco Luzza, Emidio Scarpellini
Summary: Liver transplantation is the preferred treatment for patients with certain liver conditions, but rejection after transplantation is a significant issue. The gut microbiota is involved in the gut-liver axis and can affect the immune response, potentially leading to graft rejection. Evaluating changes in the gut microbiota composition is essential for monitoring the success of liver transplantation and implementing appropriate preventive measures.
Review
Immunology
Mingjie Ding, Yuting He, Shuijun Zhang, Wenzhi Guo
Summary: Liver transplantation is an effective therapy for end-stage liver disease, but most postoperative patients require immunosuppressive drugs. Some transplant recipients achieve immune tolerance with normal liver function and no organ rejection after immunosuppressive drug withdrawal. Costimulatory molecules are crucial in T cell-mediated immune responses and tolerance maintenance, with potential for inducing immune tolerance in transplantation through costimulatory blockade.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Gastroenterology & Hepatology
Haihong Wang, Biying Zhang, Ruiqi Li, Jiayuan Chen, Guojie Xu, Ying Zhu, Jiao Li, Qing Liang, Qingling Hua, Lanqing Wang, Lu Wen, Min Jin, Jun Fan, Dejun Zhang, Lei Zhao, Dandan Yu, Zhenyu Lin, Jinghua Ren, Tao Zhang
Summary: The study found that KIAA1199 promotes CRC liver metastasis by activating the TGF beta signaling pathway and stimulating the production of CXCL1 and CXCL3, leading to increased infiltration of neutrophils. Genetic blockade or pharmacologic inhibition of KIAA1199 restored tumor immune infiltration, impeded tumor progression, and enhanced response to immune checkpoint blockade.
Article
Immunology
Soon Kyu Lee, Min-Jung Park, Jeong Won Choi, Jin-Ah Baek, Se-Young Kim, Ho Joong Choi, Young Kyoung You, Jeong Won Jang, Pil Soo Sung, Si Hyun Bae, Seung Kew Yoon, Jong Young Choi, Mi-La Cho
Summary: In this study, a patient-derived avatar model was developed to predict immune homeostasis in liver transplantation patients. The model showed promise in evaluating treatment responses and reducing risks to patients.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Rongxiao Xu, Haiming Yu, Hui Dong, Yuxi Ye, Sen Xie
Summary: This study aims to develop a cross-linked network structure material with high solidification and strong weather resistance for the curing layer after dust suppression foam treatment. Oxidized starch adhesive (OSTA) was prepared to reduce the effect of starch viscosity on foaming. OSTA, polyvinyl alcohol (PVA), glycerol (GLY), and sodium trimetaphosphate (STMP) were copolymerized, and a new material for dust suppression foam (OSPG/AA) was proposed, showing good wetting and bonding mechanism. The results demonstrate that OSPG/AA has a viscosity of 5.5 mPa.s, 30-day degradation of 43.564%, film-forming hardness of 86HA, and excellent weather resistance.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Gastroenterology & Hepatology
Masoud Khodaveisi, Mahnaz Khatiban, Mohssen Nassiri Toosi, Ali Reza Soltanian, Abbas Ebadi, Malihe Sadat Moayed
Summary: A scale for assessing adherence to care and treatment in liver transplant recipients was designed and validated through a two-phase mixed-methods study. The scale showed acceptable validity and reliability, consisting of 20 items to evaluate a four-factor structure.
Article
Surgery
Kevin Ferrari, Alice Aarnink, Carole Ayav, Luc Frimat, Cecile Couchoud, Benoit Audry, Corinne Antoine, Sophie Girerd
Summary: Continuation of immunosuppressive therapy after kidney allograft failure is associated with less change in HLA-sensitization and does not increase patient mortality.
CLINICAL TRANSPLANTATION
(2024)
Article
Surgery
Sandeep Sainathan, John Ryan, Leonardo Mullinari, Pablo Sanchez
Summary: Patients undergoing lung transplantation for pulmonary venous-occlusive disease (PVOD) had better initial survival compared to those with primary pulmonary hypertension (PPHTN), but this advantage disappeared after 1 year. The use of donation after circulatory death donors was associated with lower short-term survival rates.
CLINICAL TRANSPLANTATION
(2024)