O-GlcNAcylation and oxidation of proteins: is signalling in the cardiovascular system becoming sweeter?

O-linked β-N-acetylglucosamine supports p38 MAPK activation by high glucose in glomerular mesangial cells

(2011) Howard Goldberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The therapeutic potential of hydrogen sulfide: separating hype from hope

(2011) Kenneth R. Olson   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

S-Nitrosylation signaling regulates cellular protein interactions

(2011) Nadzeya V. Marozkina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glucosamine increases vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aorta

(2011) Do-Hyung Kim et al.   BMB Reports

dbOGAP - An Integrated Bioinformatics Resource for Protein O-GlcNAcylation

(2011) Jinlian Wang et al.   BMC BIOINFORMATICS

Design and synthesis of O-GlcNAcase inhibitors via ‘click chemistry’ and biological evaluations

(2011) Tiehai Li et al.   CARBOHYDRATE RESEARCH

O-GlcNAc modification: why so intimately associated with phosphorylation?

(2011) Suresh Mishra et al.   Cell Communication and Signaling

Epigenetic Modifications

(2011) Diane E. Handy et al.   CIRCULATION

Protein O-linked β-N-acetylglucosamine: A novel effector of cardiomyocyte metabolism and function

(2011) Victor M. Darley-Usmar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enzyme Molecular Mechanism as a Starting Point to Design New Inhibitors: A Theoretical Study ofO-GlcNAcase

(2011) Jerônimo Lameira et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Novel Post-translational Modification in Nerve Terminals: O-LinkedN-Acetylglucosamine Phosphorylation

(2011) Mark E. Graham et al.   JOURNAL OF PROTEOME RESEARCH

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

(2011) Michael B. Lazarus et al.   NATURE

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

(2011) Tracey M Gloster et al.   Nature Chemical Biology

O-GlcNAc-Specific Antibody CTD110.6 Cross-Reacts with N-GlcNAc2-Modified Proteins Induced under Glucose Deprivation

(2011) Takahiro Isono   PLoS One

O-GlcNAcylation: a novel pathway contributing to the effects of endothelin in the vasculature

(2010) Victor V. Lima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice

(2010) Susan A. Marsh et al.   AMINO ACIDS

Augmented O-GlcNAc signaling attenuates oxidative stress and calcium overload in cardiomyocytes

(2010) Gladys A. Ngoh et al.   AMINO ACIDS

Mitochondrial respiratory dysfunction-elicited oxidative stress and posttranslational protein modification in mitochondrial diseases

(2010) Yu-Ting Wu et al.   Annals of the New York Academy of Sciences

Advanced Glycation End Products Accelerate Ischemia/Reperfusion Injury Through Receptor of Advanced End Product/Nitrative Thioredoxin Inactivation in Cardiac Microvascular Endothelial Cells

(2010) Yi Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Greasing Their Way: Lipid Modifications Determine Protein Association with Membrane Rafts

(2010) Ilya Levental et al.   BIOCHEMISTRY

Modulation of transcription factor function by O-GlcNAc modification

(2010) Sabire Özcan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway

(2010) Victor V. Lima et al.   CARDIOVASCULAR RESEARCH

The paradoxical world of protein O-GlcNAcylation: a novel effector of cardiovascular (dys)function

(2010) S. A. Marsh et al.   CARDIOVASCULAR RESEARCH

O -GlcNAc Signaling in the Cardiovascular System

(2010) Gladys A. Ngoh et al.   CIRCULATION RESEARCH

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Oxidative Stress and Hypertension: Current Concepts

(2010) Ana M. Briones et al.   CURRENT HYPERTENSION REPORTS

Role of Antioxidants in Redox Regulation of Diabetic Cardiovascular Complications

(2010) Belma Turan   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells

(2010) Yunzhuo Ren et al.   FEBS LETTERS

Site-specific interplay between O-GlcNAcylation and phosphorylation in cellular regulation

(2010) Ping Hu et al.   FEBS LETTERS

Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury

(2010) So-Young Hwang et al.   GLIA

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase

(2010) Liv Ingrid Flinder et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protein tyrosine nitration in cellular signal transduction pathways

(2010) Vasily A. Yakovlev et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

O-linked β-N-acetylglucosamine During Hyperglycemia Exerts Both Anti-Inflammatory and Pro-Oxidative Properties in the Endothelial System

(2010) Angana Gupta Rajapakse et al.   Oxidative Medicine and Cellular Longevity

O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart

(2010) Lewis J. Watson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted large-scale analysis of protein acetylation

(2010) Nikolai Mischerikow et al.   PROTEOMICS

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

(2010) C. Slawson et al.   TRENDS IN BIOCHEMICAL SCIENCES

The hexosamine biosynthesis inhibitor azaserine prevents endothelial inflammation and dysfunction under hyperglycemic condition through antioxidant effects

(2009) Angana Gupta Rajapakse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death

(2009) Gladys A. Ngoh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

O-GlcNAcylation regulates hyperglycemia-induced GPX1 activation

(2009) Won Ho Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

O-GlcNAc protein modification in plants: Evolution and function

(2009) Neil E. Olszewski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

(2009) John A. Hanover et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Involvement of NADPH oxidase and protein kinase C in endothelin-1-induced superoxide production in retinal microvessels

(2009) Junko Matsuo et al.   EXPERIMENTAL EYE RESEARCH

Impaired Vasodilator Activity in Deoxycorticosterone Acetate-Salt Hypertension Is Associated With Increased Protein O-GlcNAcylation

(2009) Victor V. Lima et al.   HYPERTENSION

O-GlcNAcylation Contributes to Augmented Vascular Reactivity Induced by Endothelin 1

(2009) Victor V. Lima et al.   HYPERTENSION

O-GlcNAc Protein Modification in Cancer Cells Increases in Response to Glucose Deprivation through Glycogen Degradation

(2009) Jeong Gu Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways

(2009) Q. Zeidan et al.   JOURNAL OF CELL SCIENCE

Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure

(2009) Maria D’Apolito et al.   JOURNAL OF CLINICAL INVESTIGATION

O-GlcNAcylation: a novel post-translational mechanism to alter vascular cellular signaling in health and disease: focus on hypertension

(2009) Victor V. Lima et al.   Journal of the American Society of Hypertension

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity

(2008) Ronald J. Copeland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury

(2008) Dongqi Xing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-κB signaling

(2008) Luyun Zou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system

(2008) Boglarka Laczy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

O-GlcNAc modification of FoxO1 increases its transcriptional activity: A role in the glucotoxicity phenomenon?

(2008) MeiShiue Kuo et al.   BIOCHIMIE

Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats

(2008) Norbert Fülöp et al.   BIOGERONTOLOGY

Cardioprotection by N -Acetylglucosamine Linkage to Cellular Proteins

(2008) Steven P. Jones et al.   CIRCULATION

Unique Hexosaminidase Reduces Metabolic Survival Signal and Sensitizes Cardiac Myocytes to Hypoxia/Reoxygenation Injury

(2008) Gladys A. Ngoh et al.   CIRCULATION RESEARCH

Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination

(2008) Pavla Bojarová et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Alexander Golks et al.   EMBO REPORTS

Up-regulation ofO-GlcNAc Transferase with Glucose Deprivation in HepG2 Cells Is Mediated by Decreased Hexosamine Pathway Flux

(2008) Rodrick P. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase and p38 MAPK ActivateO-GlcNAcylation of Neuronal Proteins during Glucose Deprivation

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased vascular O-GlcNAcylation augments reactivity to constrictor stimuli — Vasoactive Peptide Symposium

(2008) Victor V. Lima et al.   Journal of the American Society of Hypertension

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

NF B activation is associated with its O-GlcNAcylation state under hyperglycemic conditions

(2008) W. H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA