Involvement of the renin–angiotensin system in abdominal and thoracic aortic aneurysms

A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation

(2012) Giulia Fornasa et al.   CARDIOVASCULAR RESEARCH

Transient Exposure of Neonatal Female Mice to Testosterone Abrogates the Sexual Dimorphism of Abdominal Aortic Aneurysms

(2012) Xuan Zhang et al.   CIRCULATION RESEARCH

Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development

(2012) Lars Maegdefessel et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

(2012) L. Maegdefessel et al.   Science Translational Medicine

Prolonged Infusion of Angiotensin II in apoE−/− Mice Promotes Macrophage Recruitment with Continued Expansion of Abdominal Aortic Aneurysm

(2011) Debra L. Rateri et al.   AMERICAN JOURNAL OF PATHOLOGY

Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation

(2011) Kathryn Maiellaro-Rafferty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Group X secretory PLA2 in neutrophils plays a pathogenic role in abdominal aortic aneurysms in mice

(2011) Kazuhiro Watanabe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MyD88 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Independent of Signaling Through Toll-Like Receptors 2 and 4

(2011) A. Phillip Owens et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Urokinase-Type Plasminogen Activator Deficiency in Bone Marrow–Derived Cells Augments Rupture of Angiotensin II–Induced Abdominal Aortic Aneurysms

(2011) Haruhito A. Uchida et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Syndecan-1 Displays a Protective Role in Aortic Aneurysm Formation by Modulating T Cell–Mediated Responses

(2011) Jiantao Xiao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms

(2011) Shaoping Wang et al.   ATHEROSCLEROSIS

A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm

(2011) M Revermann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Parsing Aortic Aneurysms

(2011) Mark W. Majesky et al.   CIRCULATION RESEARCH

MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

(2011) Reinier A. Boon et al.   CIRCULATION RESEARCH

Endothelial Cell–Specific Deficiency of Ang II Type 1a Receptors Attenuates Ang II–Induced Ascending Aortic Aneurysms in LDL Receptor −/− Mice

(2011) Debra L. Rateri et al.   CIRCULATION RESEARCH

Development of Angiotensin II-induced Abdominal Aortic Aneurysms Is Independent of Catalase in Mice

(2011) Haruhito A. Uchida et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Calpain Inhibition Attenuates Angiotensin II–induced Abdominal Aortic Aneurysms and Atherosclerosis in Low-density Lipoprotein Receptor–deficient Mice

(2011) Venkateswaran Subramanian et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Regulator of calcineurin 1 mediates pathological vascular wall remodeling

(2011) Vanesa Esteban et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Complex pathologies of angiotensin II-induced abdominal aortic aneurysms

(2011) Alan Daugherty et al.   Journal of Zhejiang University-SCIENCE B

Lessons on the pathogenesis of aneurysm from heritable conditions

(2011) Mark E. Lindsay et al.   NATURE

The role of the renin–angiotensin system in thoracic aortic aneurysms: Clinical implications

(2011) Els Moltzer et al.   PHARMACOLOGY & THERAPEUTICS

Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm

(2011) Joshua M. Spin et al.   PHYSIOLOGICAL GENOMICS

Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT1) Receptor Blockade

(2011) Els Moltzer et al.   PLoS One

Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism

(2011) J. P. Habashi et al.   SCIENCE

Cystatin C Deficiency Promotes Inflammation in Angiotensin II–Induced Abdominal Aortic Aneurisms in Atherosclerotic Mice

(2010) Stephanie Schulte et al.   AMERICAN JOURNAL OF PATHOLOGY

Weight loss in obese C57BL/6 mice limits adventitial expansion of established angiotensin II-induced abdominal aortic aneurysms

(2010) Sara B. Police et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effects of Caspase Inhibitor on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice

(2010) Dai Yamanouchi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Deletion of EP4 on Bone Marrow–Derived Cells Enhances Inflammation and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation

(2010) Eva H.C. Tang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Telomerase Deficiency in Bone Marrow–Derived Cells Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm Formation

(2010) Hannes M. Findeisen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Influences of Aortic Motion and Curvature on Vessel Expansion in Murine Experimental Aneurysms

(2010) Craig J. Goergen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Total lymphocyte deficiency attenuates AngII-induced atherosclerosis in males but not abdominal aortic aneurysms in apoE deficient mice

(2010) Haruhito A. Uchida et al.   ATHEROSCLEROSIS

Group X secretory phospholipase A2 augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice

(2010) Melissa Zack et al.   ATHEROSCLEROSIS

Complement Regulator CD59 Protects Against Angiotensin II–Induced Abdominal Aortic Aneurysms in Mice

(2010) Gongxiong Wu et al.   CIRCULATION

Pioglitazone-Induced Reductions in Atherosclerosis Occur via Smooth Muscle Cell–Specific Interaction With PPARγ

(2010) Venkateswaran Subramanian et al.   CIRCULATION RESEARCH

Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE−/−mice

(2010) Alan Daugherty et al.   CLINICAL SCIENCE

Protective effects of angiotensin-converting enzyme I/I and matrix metalloproteinase-3 6A/6A polymorphisms on dilatative pathology within the ascending thoracic aorta

(2010) Vaiva Lesauskaite et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome

(2010) H. Nistala et al.   HUMAN MOLECULAR GENETICS

The CARMA3-Bcl10-MALT1 Signalosome Promotes Angiotensin II-dependent Vascular Inflammation and Atherogenesis

(2010) Linda M. McAllister-Lucas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II–infused mice

(2010) Yu Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

In vivo quantification of murine aortic cyclic strain, motion, and curvature: Implications for abdominal aortic aneurysm growth

(2010) Craig J. Goergen et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Cellular phenotype transformation occurs during thoracic aortic aneurysm development

(2010) Jeffrey A. Jones et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome

(2010) H.H. Clarice Yang et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Aortic Adventitial Fibroblasts Participate in Angiotensin-Induced Vascular Wall Inflammation and Remodeling

(2010) Brian C. Tieu et al.   JOURNAL OF VASCULAR RESEARCH

Use of angiotensin converting enzyme inhibitors is associated with increased growth rate of abdominal aortic aneurysms

(2010) Michael J. Sweeting et al.   JOURNAL OF VASCULAR SURGERY

Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice

(2010) Edward Choke et al.   JOURNAL OF VASCULAR SURGERY

Loss of STAT1 is associated with increased aortic rupture in an experimental model of aortic dissection and aneurysm formation

(2010) Matthew J. Eagleton et al.   JOURNAL OF VASCULAR SURGERY

An analysis of drug modulation of abdominal aortic aneurysm growth through 25 years of surveillance

(2010) Andrew Thompson et al.   JOURNAL OF VASCULAR SURGERY

Klf15 Deficiency Is a Molecular Link Between Heart Failure and Aortic Aneurysm Formation

(2010) S. M. Haldar et al.   Science Translational Medicine

Hemodynamic Influences on abdominal aortic aneurysm disease: Application of biomechanics to aneurysm pathophysiology

(2010) Monica M. Dua et al.   VASCULAR PHARMACOLOGY

Perforin-Independent Extracellular Granzyme B Activity Contributes to Abdominal Aortic Aneurysm

(2009) Ciara M. Chamberlain et al.   AMERICAN JOURNAL OF PATHOLOGY

ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice

(2009) Lisa A. Cassis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Obesity Promotes Inflammation in Periaortic Adipose Tissue and Angiotensin II-Induced Abdominal Aortic Aneurysm Formation

(2009) Sara B. Police et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of Soluble Epoxide Hydrolase Attenuated Atherosclerosis, Abdominal Aortic Aneurysm Formation, and Dyslipidemia

(2009) Le-Ning Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cathepsin K gene disruption does not affect murine aneurysm formation

(2009) Lili Bai et al.   ATHEROSCLEROSIS

Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation

(2009) Fjoralba Kristo et al.   ATHEROSCLEROSIS

Peroxisome proliferator-activated receptor ligands reduce aortic dilatation in a mouse model of aortic aneurysm

(2009) Jonathan Golledge et al.   ATHEROSCLEROSIS

Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm

(2009) Catherine Rush et al.   BMC GENOMICS

Interferon-γ and the Interferon-Inducible Chemokine CXCL10 Protect Against Aneurysm Formation and Rupture

(2009) Victoria L. King et al.   CIRCULATION

Rosiglitazone Reduces the Development and Rupture of Experimental Aortic Aneurysms

(2009) Alun Jones et al.   CIRCULATION

Circulating Transforming Growth Factor-β in Marfan Syndrome

(2009) Peter Matt et al.   CIRCULATION

Fibulin-4 Deficiency Results in Ascending Aortic Aneurysms

(2009) Jianbin Huang et al.   CIRCULATION RESEARCH

Varespladib (A-002), a Secretory Phospholipase A2 Inhibitor, Reduces Atherosclerosis and Aneurysm Formation in ApoE−/− Mice

(2009) Heather Fraser et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

(2009) Brian C. Tieu et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II

(2009) Jun-o Deguchi et al.   LABORATORY INVESTIGATION

Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II–induced aortic aneurysms

(2009) Kimio Satoh et al.   NATURE MEDICINE

Understanding Abdominal Aortic Aneurysm

(2009) Neal L. Weintraub   NEW ENGLAND JOURNAL OF MEDICINE

Absence of p55 TNF Receptor Reduces Atherosclerosis, but Has No Major Effect on Angiotensin II Induced Aneurysms in LDL Receptor Deficient Mice

(2009) Sofia Xanthoulea et al.   PLoS One

Angiotensin II Type 1 Receptor 1166C Polymorphism Is Associated With Abdominal Aortic Aneurysm in Three Independent Cohorts

(2008) Gregory T. Jones et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Androgen Increases AT1a Receptor Expression in Abdominal Aortas to Promote Angiotensin II–Induced AAAs in Apolipoprotein E–Deficient Mice

(2008) Tracy Henriques et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microsomal Prostaglandin E Synthase-1 Deletion Suppresses Oxidative Stress and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation

(2008) Miao Wang et al.   CIRCULATION

In Vivo Serial Assessment of Aortic Aneurysm Formation in Apolipoprotein E–Deficient Mice via MRI

(2008) Gregory H. Turner et al.   Circulation-Cardiovascular Imaging

The role of the renin-angiotensin system in aortic aneurysmal diseases

(2008) Hong Lu et al.   CURRENT HYPERTENSION REPORTS

Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation

(2008) Elena Kaschina et al.   JOURNAL OF HYPERTENSION

Angiotensin II Blockade and Aortic-Root Dilation in Marfan's Syndrome

(2008) Benjamin S. Brooke et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice

(2007) Le-Ning Zhang et al.   ATHEROSCLEROSIS