Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats

Myocardial Morphological Characteristics and Proarrhythmic Substrate in the Rat Model of Heart Failure Due to Chronic Volume Overload

(2010) Jiri Benes et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway

(2010) Han Xiao et al.   CARDIOVASCULAR RESEARCH

Differential Cardiac Remodeling in Preload Versus Afterload

(2010) Karl Toischer et al.   CIRCULATION

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats

(2009) Yoshiaki Takewa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload

(2009) T. Doenst et al.   CARDIOVASCULAR RESEARCH

Metformin Prevents Progression of Heart Failure in Dogs

(2009) Hideyuki Sasaki et al.   CIRCULATION

Substrate–Enzyme Competition Attenuates Upregulated Anaplerotic Flux Through Malic Enzyme in Hypertrophied Rat Heart and Restores Triacylglyceride Content

(2009) Kayla M. Pound et al.   CIRCULATION RESEARCH

AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease

(2009) Aaron K. F. Wong et al.   CLINICAL SCIENCE

Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes

(2009) Hynek Strnad et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-γ dependent pathway

(2009) Ken Sugimoto et al.   JOURNAL OF HYPERTENSION

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

(2009) M L Becker et al.   PHARMACOGENOMICS JOURNAL

Toxicity and toxicokinetics of metformin in rats

(2009) Michael P. Quaile et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance

(2008) Vladimir Kus et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms

(2008) Ramesh Saeedi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

High efficiency of ROS production by glycerophosphate dehydrogenase in mammalian mitochondria

(2008) Tomáš Mráček et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Metabolic remodelling of the failing heart: beneficial or detrimental?

(2008) M. van Bilsen et al.   CARDIOVASCULAR RESEARCH

Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure

(2008) Susheel Gundewar et al.   CIRCULATION RESEARCH

Mechanisms of metformin inhibiting lipolytic response to isoproterenol in primary rat adipocytes

(2008) Tingting Zhang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY