Journal
CLINICAL RHEUMATOLOGY
Volume 30, Issue 3, Pages 399-401Publisher
SPRINGER LONDON LTD
DOI: 10.1007/s10067-010-1605-1
Keywords
Anti-TNF; Screening; TB
Categories
Ask authors/readers for more resources
Reactivation of latent tuberculosis (TB) is an established risk of anti-tumour necrosis factor alpha (anti-TNF) therapy. We report five cases of active TB occurring in 703 patients treated with anti-TNF therapy over a 10-year period in a central London hospital and review our screening practices for identifying latent TB prior to anti-TNF treatment. Four patients were receiving adalimumab and one patient etanercept at the time of TB diagnosis. Four of the five patients were born in countries with a high TB prevalence. Two of the five patients were healthcare workers. All patients had normal chest radiographs prior to anti-TNF treatment. Our data emphasise that country of origin is important in the determining risk of latent TB and that a normal chest radiograph does not exclude latent TB.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available