Article
Psychology, Clinical
Rei Monden, Judith G. M. Rosmalen, Klaas J. Wardenaar, Francis Creed
Summary: This prospective population-based study assessed the predictors of new onsets of irritable bowel syndrome (IBS), chronic fatigue syndrome (CFS), and fibromyalgia (FM). The study found that syndrome-specific predictors were more common than shared ones. The study also revealed a close relationship between IBS and FM, which requires further research.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Article
Biochemistry & Molecular Biology
Zahid Ijaz Tarar, Umer Farooq, Ahmad Nawaz, Mustafa Gandhi, Yezaz A. Ghouri, Asmeen Bhatt, Brooks D. Cash
Summary: The study found a significant correlation between IBS and fibromyalgia and chronic fatigue syndrome (CFS), with higher prevalence rates in IBS patients compared to the general adult population without IBS. Different subtypes of IBS, age, gender, and race were identified as predictors for increased odds of fibromyalgia and CFS.
Review
Psychiatry
Zarmina Islam, Adrijana D'Silva, Maitreyi Raman, Yasmin Nasser
Summary: Irritable bowel syndrome and fibromyalgia have similar pathophysiologic mechanisms and co-diagnosed patients experience more severe symptoms and decreased quality of life. Mind-body interventions, especially cognitive behavioral therapy and yoga, can improve patient-reported outcomes in both conditions individually.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Gastroenterology & Hepatology
Lin Chang, Shahnaz Sultan, Anthony Lembo, G. Nicholas Verne, Walter Smalley, Joel J. Heidelbaugh
Summary: This study aims to provide recommendations to support practitioners in the pharmacological management of IBS-C. The results indicate a strong recommendation for linaclotide and conditional recommendations for other medications.
Article
Gastroenterology & Hepatology
Michael Camilleri, Guy Boeckxstaens
Summary: This article evaluates the evidence that targeted pathophysiological mechanisms and customized treatments can be an alternative approach to treating patients with irritable bowel syndrome (IBS). The authors conducted a literature review on the mechanisms and treatments of IBS, identifying various noninvasive clinical tests that can assess the underlying mechanisms responsible for symptom generation. These mechanisms include rectal evacuation disorders, abnormal transit, visceral hypersensitivity or hypervigilance, bile acid diarrhea, sugar intolerances, barrier dysfunction, the microbiome, immune activation, and chemicals released by these mechanisms. The authors also recognized the basic molecular mechanisms contributing to these pathophysiologies, offering opportunities for interventions with medications targeted at specific food components, receptors, and potentially the microbiome. Although the evidence supporting interventions for each mechanism varies, the current state-of-the-art allows for a shift from symptom-based treatment to individualized treatment guided by pathophysiology and clinically identified biomarkers.
Review
Medicine, General & Internal
Paula Ma Rodriguez-Castillejo, Cesar Fernandez-de-las-Penas, Francisco Alburquerque-Sendin, Daiana P. Rodrigues-de-Souza
Summary: The comorbidity between FM and IBS is not considered in the eligibility criteria of clinical trials evaluating physical therapy. Improvements in the selection criteria are necessary to avoid selection bias in clinical trials involving FM patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Katsiaryna Vashkevich, Kathryn Janiuk, Nasim Maleki
Summary: This study found that irritable bowel syndrome (IBS) is significantly associated with anxiety disorders, especially in chronic pain patients with comorbid alcohol use disorders. These findings suggest that GI problems resulting from chronic alcohol use may play a key role in the comorbidity of anxiety disorders, chronic pain, and alcohol use disorders. Addressing GI problems in IBS patients with alcohol use disorders may help manage alcohol use disorders and recovery more effectively.
FRONTIERS IN MEDICINE
(2023)
Article
Obstetrics & Gynecology
M. Peters, I Mikeltadze, H. Karro, M. Saare, Andres Metspalu, Andres Metspalu, Mari Nelis, Lili Milani, Georgi Hudjashov, Tonu Esko, A. Salumets, R. Magi, T. Laisk
Summary: Despite overlapping symptoms, endometriosis and IBS have different significantly associated comorbidities, related to the organ systems primarily involved in the index diagnosis.
HUMAN REPRODUCTION
(2022)
Review
Medicine, General & Internal
Mihaela Fadgyas Stanculete, Abdulrahman Ismaiel, Stefan-Lucian Popa, Octavia Oana Capatina
Summary: Irritable bowel syndrome (IBS) is a disorder characterized by altered gut-brain interaction and dysfunction of the brain-gut-microbiota axis. Prior studies have shown significant impairments in the health-related quality of life of patients with IBS. Resilience, as a psychosocial ability, plays a crucial role in promoting health and enhancing stress response.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Juan J. Sebastian Domingo
Summary: Irritable bowel syndrome is a common functional bowel disorder with significant impact on patients' daily lives and society's economy. It is characterized by abdominal pain, bloating, and altered bowel movements, and its etiology and pathophysiological mechanism are still unknown.
Article
Multidisciplinary Sciences
Elahe Mousavi, Ammar Hassanzadeh Keshteli, Mohammadreza Sehhati, Ahmad Vaez, Peyman Adibi
Summary: This research uses an unsupervised machine learning algorithm to redefine subgroups of irritable bowel syndrome (IBS) based on upper gastrointestinal symptoms and psychological factors in addition to lower gastrointestinal symptoms. It discovered new homogeneous clusters in addition to well-known Rome sub-types for IBS.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Sholpan Omarova, Karem Awad, Verena Moos, Christoph Puening, Greta Goelz, Jorg-Dieter Schulzke, Roland Buecker
Summary: This study observed patients with persistent PI-IBS symptoms after C. jejuni infection and found that the epithelial resistance of the colon epithelium was unaltered, but the permeability of HRP increased and some inflammation-related markers were elevated. Therefore, targeting these mechanisms caused by the infection may help reduce sequelae such as PI-IBS.
Article
Multidisciplinary Sciences
A. Das, E. O'Herlihy, F. Shanahan, P. W. O'Toole, I. B. Jeffery
Summary: Alterations in the gut mycobiome were found to be significantly different between patients with Irritable Bowel Syndrome (IBS) and control subjects, but not among clinical subtypes of IBS. The mycobiome changes were significantly associated with alterations in the bacteriome and metabolome, but did not show a link with dietary habits. Despite co-variation with bacterial components, the mycobiome presents limited therapeutic and diagnostic potential for IBS.
SCIENTIFIC REPORTS
(2021)
Article
Gastroenterology & Hepatology
Qi Su, Hein M. Tun, Qin Liu, Yun Kit Yeoh, Joyce Wing Yan Mak, Francis K. L. Chan, Siew C. Ng
Summary: This study examined the association between gut microbiota and Irritable bowel syndrome (IBS) subtypes, and found that there are distinct differences in microbiota composition among different IBS subtypes. The microbial diversity is significantly reduced in IBS-D and IBS-U, but not in IBS-C. The study also identified microbial signatures associated with depression in IBS patients. Factors such as gender, age, and dietary patterns have significant effects on gut microbiota in different IBS subtypes. These findings emphasize the importance of personalized gut microbiome modulation approaches for optimal therapeutic effects in different subtypes of IBS.
Review
Environmental Sciences
Rivi Friedenberg, Leonid Kalichman, David Ezra, Oren Wacht, Deborah Alperovitch-Najenson
Summary: This article reviews the current knowledge on work-related musculoskeletal disorders (WRMDs) and non-fatal injuries in emergency medical technicians and paramedics (EMTs-Ps). The study found that back pain and injuries were common, with risk factors including lifting, working in awkward postures, loading patients, and performing cardiopulmonary resuscitation procedures. Lack of job satisfaction and social support were associated with these issues.
ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
(2022)
Article
Multidisciplinary Sciences
Ifat Klein, Leonid Kalichman, Noy Chen, Sergio Susmallian
Summary: Physical activity after breast cancer surgery can improve function and range of motion, increase self-efficacy, and help return to previous job status. The higher the intensity and frequency of physical activity, the better the results. Vigorous activity may cause axillary web syndrome but decreases the incidence of chronic pain.
SCIENTIFIC REPORTS
(2021)
Article
Rehabilitation
Deborah Alperovitch-Najenson, Chava Weiner, Leonid Kalichman
Summary: The study assessed the reliability and validity of the Hebrew version of BADIX, finding high internal consistency, test-retest reliability, and concurrent validity with RMQ and MODQ.
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2021)
Article
Oncology
Ifat Klein, Leonid Kalichman, Noy Chen, Sergio Susmallian
Summary: The study identified that upper arm morbidity following breast cancer surgery may affect up to 70% of patients, leading to issues such as chronic pain, reduced function, and decreased range of motion. Early postoperative physical therapy can reduce the risk of prolonged pain, while regular physical activity may help reduce the occurrence of long-term functional disabilities.
Article
Oncology
Ifat Klein, Leonid Kalichman, Noy Chen, Sergio Susmallian
Summary: Early physical therapy and patient education can reduce postoperative pain levels and potentially improve functional disabilities in breast cancer patients, without causing complications. Larger studies are needed for definitive results.
Article
Anatomy & Morphology
Vladimir Stoychev, Azaria Simonovich, Deborah Alperovitch-Najenson, Michal Tzelnik, Leonid Kalichman
Summary: The study focused on developing a grading scale for assessing degenerative changes in uncovertebral joints on CT scans and evaluating the reliability of this scale. The results showed that the developed grading scale had good intra- and inter-rater reliability, with 77.6% of evaluated UVJs exhibiting degenerative changes.
Review
Clinical Neurology
Anat Kaplun, Deborah Alperovitch-Najenson, Leonid Kalichman
Summary: The review suggests that guided imagery (GI) is a safe, non-invasive technique that can help manage pain, depression, stress, fatigue, anxiety, reduce medication use, improve general well-being, wellness, and quality of life in patients with musculoskeletal disorders. Further investigations of GI mechanisms are recommended.
CURRENT PAIN AND HEADACHE REPORTS
(2021)
Article
Rehabilitation
Deborah Alperovitch-Najenson, Shani Milyoner, Dafna Horesh-Sztulman, Omer Weissberger, David Ezra, Leonid Kalichman
Summary: This study determines the importance of bed height adjustment for maintaining a neutral lumbar position according to anthropometric dimensions. Specific anatomical landmarks are recommended for bed height adjustment. Further studies are required to validate the results.
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2022)
Review
Rehabilitation
Kobi Weiss, Leonid Kalichman
Summary: The study found that deep fascial tissues are richly innervated and produce long-lasting pain responses to various stimuli, potentially serving as a source of pain in different pathologies and pain syndromes.
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2021)
Article
Environmental Sciences
Chen Lavi, Michal Elboim-Gabyzon, Yuval Naveh, Leonid Kalichman
Summary: The study investigated the effect of long-duration neuromuscular electric stimulation (NMES) on shoulder subluxation and upper-extremity function during the acute post-stroke stage. The results showed that shoulder subluxation was significantly reduced, while upper-extremity function was significantly improved in the experimental group compared to the control group. These findings suggest that supplementing NMES to standard rehabilitation and external shoulder support is beneficial in reducing shoulder subluxation and improving upper-extremity function.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Nehama Milson, Iuly Treger, Michal Vered, Asaf Acker, Leonid Kalichman
Summary: This study evaluated the efficacy of hospital-based rehabilitation for flail chest patients who had undergone open reduction and internal fixation surgery. Significant reduction in pain and improvement in functional independence and balance were observed. All patients were able to independently perform activities of daily living upon discharge.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Nursing
Anat Kaplun, Svetlana Trosman, Tatiana Reitblat, Alan Friedman, Leonid Kalichman
Summary: This study aimed to evaluate the impact of guided imagery (GI) on chronic back pain symptoms. The results showed that brief guided imagery intervention can help alleviate chronic back pain, reduce anxiety, and improve daily activity in patients.
PAIN MANAGEMENT NURSING
(2023)
Article
Anatomy & Morphology
Azaria Simonovich, Yulia Naveh, Leonid Kalichman
Summary: The study found that osteophytes in the thoracic spine are common in older adults, with the number and size increasing with age in both sexes. Osteophytes are significantly larger on the right side than the left, possibly due to proximity to the aorta.
Review
Rehabilitation
Ifat Klein, Dorit Tidhar, Leonid Kalichman
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2020)
Review
Rehabilitation
Dor Vadas, Leonid Kalichman
INTERNATIONAL JOURNAL OF THERAPY AND REHABILITATION
(2020)
