Type I Interferons: Beneficial in Th1 and Detrimental in Th17 Autoimmunity

Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

(2011) S. G. Nanjappa et al.   BLOOD

Interferon Beta Treatment in Neuromyelitis Optica

(2010) Jacqueline Palace et al.   ARCHIVES OF NEUROLOGY

Interleukin-7 Permits Th1/Tc1 Maturation and Promotes Ex vivo Expansion of Cord Blood T Cells: A Critical Step toward Adoptive Immunotherapy after Cord Blood Transplantation

(2010) C. C. Davis et al.   CANCER RESEARCH

IL-7Rα confers susceptibility to experimental autoimmune encephalomyelitis

(2010) C C Walline et al.   GENES AND IMMUNITY

Suppression of inflammation in ulcerative colitis by interferon- -1a is accompanied by inhibition of IL-13 production

(2010) P. J. Mannon et al.   GUT

Human Th17 Cells Comprise Heterogeneous Subsets Including IFN- -Producing Cells with Distinct Properties from the Th1 Lineage

(2010) K. Boniface et al.   JOURNAL OF IMMUNOLOGY

IL-17 Activates the Canonical NF-κB Signaling Pathway in Autoimmune B Cells of BXD2 Mice To Upregulate the Expression of Regulators of G-Protein Signaling 16

(2010) Shutao Xie et al.   JOURNAL OF IMMUNOLOGY

Humoral autoimmunity in multiple sclerosis

(2010) Edgar Meinl et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Adjuvant treatment suppresses IL-17 production by T cell-independent myeloid sources in nonobese diabetic mice

(2010) Xiaogang Gao et al.   MOLECULAR IMMUNOLOGY

Preferential increase of B-cell activating factor in the cerebrospinal fluid of neuromyelitis optica in a white population

(2010) Adi Vaknin-Dembinsky et al.   Multiple Sclerosis Journal

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease

(2010) Xuebin Liu et al.   NATURE MEDICINE

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

IFN -1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum

(2010) J. Shimizu et al.   NEUROLOGY

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

Heterogeneous, Longitudinally Stable Molecular Signatures in Response to Interferon-β

(2009) M. R. Sandhya Rani et al.   Annals of the New York Academy of Sciences

A type I interferon signature in monocytes is associated with poor response to interferon-β in multiple sclerosis

(2009) M. Comabella et al.   BRAIN

New-onset psoriasis in a patient treated with interferon beta-1a

(2009) I. López-Lerma et al.   BRITISH JOURNAL OF DERMATOLOGY

Interleukin-17 causes neutrophil mediated inflammation in ovalbumin-induced uveitis in DO11.10 mice

(2009) Zili Zhang et al.   CYTOKINE

Different responses to interferon beta-1b treatment in patients with neuromyelitis optica and multiple sclerosis

(2009) A. Uzawa et al.   EUROPEAN JOURNAL OF NEUROLOGY

IFN-  Inhibits Human Th17 Cell Differentiation

(2009) V. S. Ramgolam et al.   JOURNAL OF IMMUNOLOGY

Psoriasis during interferon beta treatment for multiple sclerosis

(2009) Loredana La Mantia et al.   NEUROLOGICAL SCIENCES

Clinical trial: a multicentre, randomized, double-blind, placebo-controlled, dose-finding, phase II study of subcutaneous interferon-β-1a in moderately active ulcerative colitis

(2008) C. PENA-ROSSI et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Recent Advances in the Genetics of Autoimmune Disease

(2008) Peter K. Gregersen et al.   Annual Review of Immunology

Interferon-β increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity

(2008) M. Krumbholz et al.   BRAIN

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

(2008) Marco Prinz et al.   IMMUNITY

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

(2008) Beichu Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis

(2008) Rajan P. Nair et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

(2008) Benjamin M Segal et al.   LANCET NEUROLOGY

Beta interferon restricts the inflammatory potential of CD4+ cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells

(2008) Francisco M. Martín-Saavedra et al.   MOLECULAR IMMUNOLOGY

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

(2008) Ingunn M Stromnes et al.   NATURE MEDICINE