Animal Models in Autoimmune Diseases: Lessons Learned from Mouse Models for Sjögren’s Syndrome

Identification of IL-18 and Th17 Cells in Salivary Glands of Patients with Sjogren's Syndrome, and Amplification of IL-17-Mediated Secretion of Inflammatory Cytokines from Salivary Gland Cells by IL-18

(2014) A. Sakai et al.   JOURNAL OF IMMUNOLOGY

Effect of Soluble ICAM-1 on a Sjögren's Syndrome-like Phenotype in NOD Mice Is Disease Stage Dependent

(2011) Nienke Roescher et al.   PLoS One

Pathogenic effect of interleukin-17A in induction of Sjögren's syndrome-like disease using adenovirus-mediated gene transfer

(2011) Cuong Q Nguyen et al.   ARTHRITIS RESEARCH & THERAPY

Modeling Sjögren's syndrome with Id3 conditional knockout mice

(2010) Zengli Guo et al.   IMMUNOLOGY LETTERS

Immunotherapeutic targets in estrogen deficiency-dependent Sjögren’s syndrome-related manifestations

(2010) Rieko Arakaki et al.   Immunotherapy

Pathogenic role of immune response to M3 muscarinic acetylcholine receptor in Sjögren’s syndrome-like sialoadenitis

(2010) Mana Iizuka et al.   JOURNAL OF AUTOIMMUNITY

A Role for Lymphotoxin in Primary Sjogren's Disease

(2010) L. Shen et al.   JOURNAL OF IMMUNOLOGY

Phosphatidylinositol 3-Kinase Signaling in Thymocytes: The Need for Stringent Control

(2010) E. Fayard et al.   Science Signaling

Systemic and Local Interleukin-17 and Linked Cytokines Associated with Sjögren’s Syndrome Immunopathogenesis

(2009) Gikas E. Katsifis et al.   AMERICAN JOURNAL OF PATHOLOGY

Sjögren’s syndrome: An old tale with a new twist

(2009) Byung Ha Lee et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Fine tuning the immune response with PI3K

(2009) David A. Fruman et al.   IMMUNOLOGICAL REVIEWS

Gene expression and chromosomal location for susceptibility to Sjögren's syndrome

(2009) Paola Pérez et al.   JOURNAL OF AUTOIMMUNITY

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

(2009) Alexander Espinosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential gene expression in the salivary gland during development and onset of xerostomia in Sjögren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse

(2009) Cuong Q Nguyen et al.   ARTHRITIS RESEARCH & THERAPY

Salivary gland tissue expression of interleukin-23 and interleukin-17 in Sjögren's syndrome: Findings in humans and mice

(2008) Cuong Q. Nguyen et al.   ARTHRITIS AND RHEUMATISM

IL-14 alpha, the nexus for primary Sjögren's disease in mice and humans

(2008) Long Shen et al.   CLINICAL IMMUNOLOGY

Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome

(2008) Youcun Qian et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory caspases are critical for enhanced cell death in the target tissue of Sjögren's syndrome before disease onset

(2008) Marievic Bulosan et al.   IMMUNOLOGY AND CELL BIOLOGY

Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy

(2008) Naozumi Ishimaru et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Is Inhibitor of differentiation 3 involved in human primary Sjögren's syndrome?

(2008) J. Sellam et al.   RHEUMATOLOGY

Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations

(2008) Nicolas Delaleu et al.   ARTHRITIS RESEARCH & THERAPY

Stress as a trigger of autoimmune disease

(2007) Ljudmila Stojanovich et al.   AUTOIMMUNITY REVIEWS