☆ 4.5 Letter

Effect of percutaneous renal denervation on blood pressure level and sympathetic activity in a patient with polycystic kidney disease

CLINICAL RESEARCH IN CARDIOLOGY (2014)

Journal

CLINICAL RESEARCH IN CARDIOLOGY

Volume 103, Issue 3, Pages 251-253

Publisher

SPRINGER HEIDELBERG

DOI: 10.1007/s00392-013-0647-1

Keywords

-

Categories

Cardiac & Cardiovascular Systems

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Article Peripheral Vascular Disease

Increase in Bioavailability of Nitric Oxide After Renal Denervation Improves Kidney Function in Sheep With Hypertensive Kidney Disease

Reetu R. Singh, Zoe M. McArdle, Lindsea C. Booth, Clive N. May, Geoff A. Head, Karen M. Moritz, Markus P. Schlaich, Kate M. Denton

Summary: The study showed that renal denervation (RDN) in sheep with hypertensive chronic kidney disease normalized NO bioavailability and restored the contribution of NO to renal hemodynamics. This improvement in NO levels may promote enhancements in kidney function and sustained blood pressure lowering after RDN in hypertensive CKD.

HYPERTENSION (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Effect of Heart Rate on the Outcome of Renal Denervation in Patients With Uncontrolled Hypertension

Michael Boehm, Konstantinos Tsioufis, David E. Kandzari, Kazuomi Kario, Michael A. Weber, Roland E. Schmieder, Raymond R. Townsend, Saarraaken Kulenthiran, Christian Ukena, Stuart Pocock, Sebastian Ewen, Joachim Weil, Martin Fahy, Felix Mahfoud

Summary: This analysis evaluated the impact of baseline heart rate on blood pressure reduction after renal denervation. The results showed a greater reduction in blood pressure at 3 months post renal denervation for patients with baseline heart rate >= 70 beats/min.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

Add to Collection

Review Peripheral Vascular Disease

Obstructive Sleep Apnea-Induced Neurogenic Nocturnal Hypertension A Potential Role of Renal Denervation?

Kazuomi Kario, Douglas A. Hettrick, Aleksander Prejbisz, Andrzej Januszewicz

Summary: There is a bidirectional, causal relationship between obstructive sleep apnea (OSA) and hypertension, with hypoxia/hypercapnia-related sympathetic activation being the key mechanism. While continuous positive airway pressure is the gold standard therapy for OSA, its effects on blood pressure are modest. Antihypertensive agents targeting sympathetic pathways or the renin-angiotensin-aldosterone system may have potential in patients with comorbid hypertension and OSA.

HYPERTENSION (2021)

Add to Collection

Article Peripheral Vascular Disease

Catheter-Based Renal Denervation: 9-Year Follow-Up Data on Safety and Blood Pressure Reduction in Patients With Resistant Hypertension

Gianni Sesa-ashton, Janis M. Nolde, Ida Muente, Revathy Carnagarin, Rebecca Lee, Vaughan G. Macefield, Tye Dawood, Yusuke Sata, Elisabeth A. Lambert, Gavin W. Lambert, Antony Walton, Marcio G. Kiuchi, Murray D. Esler, Markus P. Schlaich

Summary: Long-term follow-up studies on catheter-based renal denervation in patients with resistant hypertension show that the method can still effectively reduce blood pressure and decrease medication usage after nearly 9 years of follow-up, without any adverse effects on renal function.

HYPERTENSION (2023)

Add to Collection

Article Peripheral Vascular Disease

Evidence of Reduced Efferent Renal Sympathetic Innervation After Chemical Renal Denervation in Humans

Christopher M. Hearon, Erin J. Howden, Qi Fu, Jeung-Ki Yoo, Katrin A. Dias, Monique A. Roberts-Reeves, Mitchel Samels, Satyam Sarma, Shawna Nesbitt, Wanpen Vongpatanasin, David S. Goldstein, Tayo Addo, Benjamin D. Levine

Summary: The study investigated the sympathetic innervation of the renal cortex following renal denervation (RDN) in humans, showing efferent sympathetic denervation of the kidneys. This finding may help explain the variability in blood pressure lowering effects observed in clinical trials.

AMERICAN JOURNAL OF HYPERTENSION (2021)

Add to Collection

Review Peripheral Vascular Disease

Effects of Renal Denervation on Sympathetic Nerve Traffic and Correlates in Drug-Resistant and Uncontrolled Hypertension: A Systematic Review and Meta-Analysis

Annalisa Biffi, Raffaella Dell'Oro, Fosca Quarti-Trevano, Cesare Cuspidi, Giovanni Corrao, Giuseppe Mancia, Guido Grassi

Summary: This meta-analysis demonstrates that renal denervation (RDN) is associated with a significant, although modest, central sympathoinhibition in a consistent number of drug-resistant or uncontrolled hypertension patients. However, this effect is unrelated to the blood pressure lowering effects of RDN. Factors other than central sympathetic outflow inhibition may contribute to the BP lowering effects of RDN.

HYPERTENSION (2023)

Add to Collection

Review Urology & Nephrology

Renal Denervation: A Review

Jimena Rey, Raymond R. Townsend

Summary: Uncontrolled hypertension remains a significant health problem despite the availability of various medications and therapies. Device-based methods that denervate the renal arteries are emerging as potential alternatives to standard antihypertensive treatments, which often require daily medication or physical activity. This review summarizes the mechanisms, efficacy, and safety of renal artery denervation, and discusses the challenges in this rapidly evolving field.

AMERICAN JOURNAL OF KIDNEY DISEASES (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Validation of a Novel Renal Denervation System With Cryoablation A Preclinical Study and Case Series

Meng Ji, Han Chen, Li Shen, Yi Zhang, Zhifeng Yao, Yizhe Wu, Yawei Xu, Junbo Ge

Summary: In this study, a renal denervation with cryoablation system was designed and proved to be effective and safe in short-term follow-up. It successfully reduced renal sympathetic nerve activity and showed preliminary safety in patients with resistant hypertension.

JACC-BASIC TO TRANSLATIONAL SCIENCE (2022)

Add to Collection

Article Peripheral Vascular Disease

Transurethral Renal Pelvic Denervation: A Feasibility Trial in Patients with Uncontrolled Hypertension

Dagmara Hering, David Nikoleishvili, Avtandil Imedadze, Gvantsa Dughashvili, Zurab Klimiashvili, Eter Bekaia, Tamar Shengelia, Mamuka Kobalava, Otar Goguadze, Tamar Emukhvari, Vitaly Druker, Jonathan Sackner-Bernstein, Michael A. Weber

Summary: Renal denervation using radiofrequency energy delivered across the renal pelvis through the natural orifice of the urethra and the ureters effectively reduces blood pressure and may be a potential treatment option for patients with uncontrolled hypertension despite drug therapy.

HYPERTENSION (2022)

Add to Collection

Article Peripheral Vascular Disease

A Japan nationwide web-based survey of patient preference for renal denervation for hypertension treatment

Kazuomi Kario, Hideaki Kagitani, Shoko Hayashi, Satsuki Hanamura, Keisuke Ozawa, Hiroshi Kanegae

Summary: The study found that a significant proportion of Japanese patients with hypertension expressed a preference for renal denervation. Patients who preferred this treatment were typically younger, male, had higher blood pressure, had poor adherence to antihypertensive drugs, had heart failure, and experienced side effects from antihypertensive medications.

HYPERTENSION RESEARCH (2022)

Add to Collection

Review Cardiac & Cardiovascular Systems

Effect of renal denervation for patients with isolated systolic hypertension: a systematic review and meta-analysis

Le Li, Yu-Long Xiong, Bin Tu, Shang-Yu Liu, Zhen-Hao Zhang, Zhao Hu, Yan Yao

Summary: This meta-analysis investigates the efficacy of renal denervation (RDN) in patients with isolated systolic hypertension (ISH) compared to patients with combined systolic and diastolic hypertension (CH). The results show that RDN is more effective in controlling blood pressure in patients with CH, suggesting that these patients may be the optimal population for RDN treatment. This finding has important implications for the application of RDN in clinical practice.

JOURNAL OF GERIATRIC CARDIOLOGY (2023)

Add to Collection

Review Cardiac & Cardiovascular Systems

Update on Renal Sympathetic Denervation for the Treatment of Hypertension

Arundati Rao, Namrata Krishnan

Summary: Renal sympathetic denervation (RDN) has been explored as a therapeutic strategy in the treatment of hypertension and has shown promising results in lowering blood pressure. However, its use as a primary treatment approach is currently limited due to its modest treatment effect and concerns about long-term sustainability.

CURRENT CARDIOLOGY REPORTS (2022)

Add to Collection

Article Multidisciplinary Sciences

Renal artery denervation prevents ventricular arrhythmias in long QT rabbit models

An Nu-Khanh Ton, Shin-Huei Liu, Li-Wei Lo, Thien Chuong-Nguyen Khac, Yu-Hui Chou, Wen-Han Cheng, Wei-Lun Lin, Tzu-Yen Peng, Pin-Yi Lin, Shih-Lin Chang, Shih-Ann Chen

Summary: Renal artery denervation (RDN) leads to electrical remodeling and reduces ventricular arrhythmia (VA) inducibility in LQTS models.

SCIENTIFIC REPORTS (2022)

Add to Collection

Article Peripheral Vascular Disease

Renal Denervation in Combination With Angiotensin Receptor Blockade Prolongs Blood Pressure Trough During Hemorrhage

Reetu R. Singh, Zoe McArdle, Lindsea C. Booth, Clive N. May, Geoff A. Head, Karen M. Moritz, Markus P. Schlaich, Kate M. Denton

Summary: Patients with hypertension and chronic kidney disease who undergo renal denervation may have impaired hemodynamic responses to blood loss if they continue taking antihypertensive medication. Therefore, closer monitoring is necessary during surgery or traumatic blood loss in these patients to minimize the risk of hypotension-mediated organ damage.

HYPERTENSION (2022)

Add to Collection

Article Medicine, Research & Experimental

Renal nerve stimulation identifies renal innervation and optimizes the strategy for renal denervation in canine

Hang Liu, Yidan Li, Hao Zhou, Weijie Chen, Yanping Xu, Huaan Du, Bo Zhang, Tianli Xia, Dan Li, Zhenhong Ou, Ruotian Tang, Qingsong Chen, Binyi Zhao, Yuehui Yin

Summary: This study explores the characteristics of renal autonomic innervation at different blood pressure response sites and finds that renal nerve stimulation is an effective method for identifying renal autonomic innervation. It can help determine the optimal treatment target during renal denervation by avoiding ablation of sympathetic-inhibitory areas.

JOURNAL OF TRANSLATIONAL MEDICINE (2023)

Add to Collection

Article Endocrinology & Metabolism

Fibrin clot properties and fibrinolysis in patients with endocrine hypertension due to aldosterone or catecholamines excess

Ewa Warchol-Celinska, Aleksander Prejbisz, Piotr Dobrowolski, Ewa Wypasek, Jacek Kadziela, Sylwia Kolodziejczyk-Kruk, Marek Kabat, Anetta Undas, Andrzej Januszewicz

Summary: The study found that patients with PA and PPGL are at a prothrombic state comparable to patients with EHT, with more compact clot structure, faster clot formation, and enhanced thrombin generation. The results suggest that the higher risk of cardiovascular events observed in hypertensive PA and PPGL compared to EHT is not mediated through investigated prothrombic mechanisms.

CLINICAL ENDOCRINOLOGY (2022)

Add to Collection

Article Oncology

Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine

Susan Richter, Bei Qiu, Mirthe Ghering, Carola Kunath, Georgiana Constantinescu, Charlotte Luths, Christina Pamporaki, Nicole Bechmann, Leah Meuter, Aleksandra Kwapiszewska, Timo Deutschbein, Svenja Noelting, Mirko Peitzsch, Mercedes Robledo, Aleksander Prejbisz, Karel Pacak, Volker Gudziol, Henri J. L. M. Timmers, Graeme Eisenhofer

Summary: Jugulotympanic HNPGLs have distinct features, primarily occurring in women and having a lower proportion of SDHx mutations. Compared to carotid body and vagal HNPGLs, jugulotympanic HNPGLs are less likely to be bilateral, smaller in size, and have a lower metastatic rate. Patients with HNPGLs have higher plasma concentrations of MTY, while plasma normetanephrine does not differ significantly.

ENDOCRINE-RELATED CANCER (2022)

Add to Collection

Article Peripheral Vascular Disease

Blood Pressure and Arterial Stiffness in Association With Aircraft Noise Exposure:Long-Term Observation and Potential Effect of COVID-19 Lockdown

Wiktoria Wojciechowska, Andrzej Januszewicz, Tomasz Drozdz, Marta Rojek, Justyna Baczalska, Michal Terlecki, Karol Kurasz, Agnieszka Olszanecka, Mikolaj Smolski, Aleksander Prejbisz, Piotr Dobrowolski, Tomasz Grodzicki, Tomasz Hryniewiecki, Reinhold Kreutz, Marek Rajzer

Summary: This study reveals the association between long-term exposure to aircraft noise and increased prevalence of hypertension and arterial stiffening. However, even short-term noise reduction during the COVID-19 lockdown can reverse these unfavorable effects.

HYPERTENSION (2022)

Add to Collection

Article Endocrinology & Metabolism

Plasma Steroid Profiling in Patients With Adrenal Incidentaloma

Kristina Berke, Georgiana Constantinescu, Jimmy Masjkur, Otilia Kimpel, Ulrich Dischinger, Mirko Peitzsch, Aleksandra Kwapiszewska, Piotr Dobrowolski, Svenja Nolting, Martin Reincke, Felix Beuschlein, Stefan R. Bornstein, Aleksander Prejbisz, Jacques W. M. Lenders, Martin Fassnacht, Graeme Eisenhofer

Summary: Plasma steroid profiling combined with metanephrines and adrenal tumor size can be used for the differential diagnosis of patients with adrenal incidentaloma. This approach shows high sensitivity and specificity for identifying different types of adrenal tumors.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Add to Collection

Article Endocrinology & Metabolism

The Saline Infusion Test for Primary Aldosteronism: Implications of Immunoassay Inaccuracy

Graeme Eisenhofer, Max Kurlbaum, Mirko Peitzsch, Georgiana Constantinescu, Hanna Remde, Manuel Schulze, Denise Kaden, Lisa Marie Mueller, Carmina T. Fuss, Sonja Kunz, Sylwia Kolodziejczyk-Kruk, Sven Gruber, Aleksander Prejbisz, Felix Beuschlein, Tracy Ann Williams, Martin Reincke, Jacques W. M. Lenders, Martin Bidlingmaier

Summary: This study found discrepancies between immunoassay and mass spectrometry measurements of plasma aldosterone may impact confirmatory testing for PA. Immunoassays could lead to misdiagnosis in over 60% of patients, but plasma purification eliminates this inaccuracy.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Add to Collection

Article Peripheral Vascular Disease

Improved Diagnostic Accuracy of Clonidine Suppression Testing Using an Age-Related Cutoff for Plasma Normetanephrine

Hanna Remde, Christina Pamporaki, Marcus Quinkler, Svenja Nolting, Aleksander Prejbisz, Henri J. L. M. Timmers, Jimmy Masjkur, Carmina T. Fuss, Martin Fassnacht, Graeme Eisenhofer, Timo Deutschbein

Summary: This study aimed to evaluate the diagnostic outcome of CST in patients with moderate NMN elevations, showing high sensitivity and specificity in diagnosing PPGL.

HYPERTENSION (2022)

Add to Collection

Article Peripheral Vascular Disease

2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action

Norm R. C. Campbell, Paul K. Whelton, Marcelo Orias, Richard D. Wainford, Francesco P. Cappuccio, Nicole Ide, Bruce Neal, Jennifer Cohn, Laura K. Cobb, Jacqui Webster, Kathy Trieu, Feng J. He, Rachael M. McLean, Adriana Blanco-Metzler, Mark Woodward, Nadia Khan, Yoshihiro Kokubo, Leo Nederveen, JoAnne Arcand, Graham A. MacGregor, Mayowa O. Owolabi, Liu Lisheng, Gianfranco Parati, Daniel T. Lackland, Fadi J. Charchar, Bryan Williams, Maciej Tomaszewski, Cesar A. Romero, Beatriz Champagne, Mary R. L'Abbe, Michael A. Weber, Markus P. Schlaich, Agnes Fogo, Valery L. Feigin, Rufus Akinyemi, Felipe Inserra, Bindu Menon, Marcia Simas, Mario Fritsch Neves, Krassimira Hristova, Carolyn Pullen, Sanjay Pandeya, Junbo Ge, Jorge E. Jalil, Ji-Guang Wang, Jiri Wideimsky, Reinhold Kreutz, Ulrich Wenzel, Michael Stowasser, Manuel Arango, Athanasios Protogerou, Eugenia Gkaliagkousi, Flavio Danni Fuchs, Mansi Patil, Andy Wai-Kwong Chan, Janos Nemcsik, Ross T. Tsuyuki, Sanjeevi Nathamuni Narasingan, Nizal Sarrafzadegan, Maria Eugenia Ramos, Natalie Yeo, Hiromi Rakugi, Agustin J. Ramirez, Guillermo Alvarez, Adel Berbari, Cho-il Kim, Sang-Hyun Ihm, Yook-Chin Chia, Tsolmon Unurjargal, Hye Kyung Park, Kolawole Wahab, Helen McGuire, Naranjargal J. Dashdorj, Mohammed Ishaq, Deborah Ignacia D. Ona, Leilani B. Mercado-Asis, Aleksander Prejbisz, Marianne Leenaerts, Carla Simao, Fernando Pinto, Bader Ali Almustafa, Jonas Spaak, Stefan Farsky, Dragan Lovic, Xin-Hua Zhang

JOURNAL OF HUMAN HYPERTENSION (2023)

Add to Collection

Editorial Material Cardiac & Cardiovascular Systems

Altered monocytic phenotypes are linked to a hypertension form: A clinical observational study

Anna M. Imiela, Mateusz Siedlinski, Piotr Dobrowolski, Barbara Pregowska-Chwala, Marek Kabat, Renee Nazare Oliveira Silva, Ankita Maria Koshy, Aleksandra Wrobel, Iwona Cendrowska-Demkow, Magdalena Januszewicz, Andrzej Januszewicz, Aleksander Prejbisz, Tomasz P. Mikolajczyk

KARDIOLOGIA POLSKA (2022)

Add to Collection

Correction Multidisciplinary Sciences

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases (vol 12, 6031, 2021)

Adrien Georges, Min-Lee Yang, Takiy-Eddine Berrandou, Mark K. Bakker, Ozan Dikilitas, Soto Romuald Kiando, Lijiang Ma, Benjamin A. Satterfield, Sebanti Sengupta, Mengyao Yu, Jean-Francois Deleuze, Delia Dupre, Kristina L. Hunker, Sergiy Kyryachenko, Lu Liu, Ines Sayoud-Sadeg, Laurence Amar, Chad M. Brummett, Dawn M. Coleman, Valentina d'Escamard, Peter de Leeuw, Natalia Fendrikova-Mahlay, Daniella Kadian-Dodov, Jun Z. Li, Aurelien Lorthioir, Marco Pappaccogli, Aleksander Prejbisz, Witold Smigielski, James C. Stanley, Matthew Zawistowski, Xiang Zhou, Sebastian Zollner, Philippe Amouyel, Marc L. De Buyzere, Stephanie Debette, Piotr Dobrowolski, Wojciech Drygas, Heather L. Gornik, Jeffrey W. Olin, Jerzy Piwonski, Ernst R. Rietzschel, Ynte M. Ruigrok, Miikka Vikkula, Ewa Warchol Celinska, Andrzej Januszewicz, Iftikhar J. Kullo, Michel Azizi, Xavier Jeunemaitre, Alexandre Persu, Jason C. Kovacic, Santhi K. Ganesh, Nabila Bouatia-Naji

NATURE COMMUNICATIONS (2022)

Add to Collection

Article Endocrinology & Metabolism

Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma

Georg Pommer, Christina Pamporaki, Mirko Peitzsch, Hanna Remde, Timo Deutschbein, Svenja Noelting, Lisa Marie Mueller, Leah Braun, Sven Gruber, Alessio Pecori, Stephanie Hampson, Eleanor Davies, Anthony Stell, Gian Paolo Rossi, Livia Lenzini, Filippo Ceccato, Henri J. L. M. Timmers, Jaap Deinum, Laurence Amar, Anne Blanchard, Stephanie Baron, Martin Fassnacht, Piotr Dobrowolski, Andrzej Januszewicz, Maria-Christina Zennaro, Aleksander Prejbisz, Graeme Eisenhofer

Summary: This study aimed to identify preanalytical precautions to minimize false-positive results for plasma metanephrines in patients with PPGL. The results showed that outpatient sampling, low temperature, semi-recumbent position, and direct venipuncture were associated with higher plasma concentrations and rates of false-positive results.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Cardiovascular profile of patients with unilateral four renal arteries. A systematic study

Pawel Tyczynski, Krzysztof Kukula, Jacek Kadziela, Ilona Kowalik, Pawel Kwiatek, Justyna Gruczek, Paulina Talarowska, Jaroslaw Skowronski, Adam Witkowski, Ilona Michalowska

KARDIOLOGIA POLSKA (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Preanalytical Pitfalls in Untargeted Plasma Nuclear Magnetic Resonance Metabolomics of Endocrine Hypertension

Nikolaos G. Bliziotis, Leo A. J. Kluijtmans, Gerjen H. Tinnevelt, Parminder Reel, Smarti Reel, Katharina Langton, Mercedes Robledo, Christina Pamporaki, Alessio Pecori, Josie Van Kralingen, Martina Tetti, Udo F. H. Engelke, Zoran Erlic, Jasper Engel, Timo Deutschbein, Svenja Noelting, Aleksander Prejbisz, Susan Richter, Jerzy Adamski, Andrzej Januszewicz, Filippo Ceccato, Carla Scaroni, Michael C. Dennedy, Tracy A. Williams, Livia Lenzini, Anne-Paule Gimenez-Roqueplo, Eleanor Davies, Martin Fassnacht, Hanna Remde, Graeme Eisenhofer, Felix Beuschlein, Matthias Kroiss, Emily Jefferson, Maria-Christina Zennaro, Ron A. Wevers, Jeroen J. Jansen, Jaap Deinum, Henri J. L. M. Timmers

Summary: This study aimed to establish signatures for different forms of endocrine hypertension (EHT) and investigate unbiased disease biomarkers. Plasma samples from 13 biobanks across seven countries were analyzed using untargeted NMR metabolomics. While signatures that could differentiate different forms of EHT were found, confounding effects related to sample center and age were also identified. Various approaches were applied to correct these confounding effects, but no biomarkers for differentiating primary hypertension from EHT could be identified.

METABOLITES (2022)

Add to Collection

Article Peripheral Vascular Disease

Impact of Arterial Hypertension and Use of Antihypertensive Pharmacotherapy on Mortality in Patients Hospitalized due to COVID-19: The CRACoV-HHS Study

Wiktoria Wojciechowska, Michal Terlecki, Marek Klocek, Agnieszka Pac, Agnieszka Olszanecka, Katarzyna Stolarz-Skrzypek, Marek Jastrzebski, Piotr Jankowski, Aleksandra Ostrowska, Tomasz Drozdz, Aleksander Prejbisz, Piotr Dobrowolski, Andrzej Januszewicz, Marcin Krzanowski, Maciej T. Malecki, Tomasz Grodzicki, Reinhold Kreutz, Marek Rajzer

Summary: This study analyzed data from 5191 patients hospitalized due to COVID-19 and found that while preexisting hypertension itself had no significant impact on in-hospital mortality among patients with COVID-19, treatment with any first-line blood pressure-lowering drug had a profound beneficial effect on survival in patients with hypertension.

HYPERTENSION (2022)

Add to Collection

Article Endocrinology & Metabolism

Recurrent Disease in Patients With Sporadic Pheochromocytoma and Paraganglioma

Minghao Li, Tamara Prodanov, Leah Meuter, Michiel N. Kerstens, Nicole Bechmann, Aleksander Prejbisz, Hanna Remde, Henri J. L. M. Timmers, Svenja Noelting, Sara Talvacchio, Annika M. A. Berends, Stephanie Fliedner, Mercedes Robledo, Jacques W. M. Lenders, Karel Pacak, Graeme Eisenhofer, Christina Pamporaki

Summary: This study found that the prevalence of recurrence in patients with sporadic PPGL is lower than in patients with pathogenic variants, but similar to those with variants that activate kinase pathways. Noradrenergic/dopaminergic phenotype, larger size, and extra-adrenal location of primary tumors were identified as independent predictors of recurrence in sporadic PPGL.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2023)

Add to Collection

Meeting Abstract Medical Laboratory Technology

UPLC-MS/MS method for simultaneous determination of 12 steroid hormones using modified commercially manufactured kit

J. Was, M. Niedolistek, A. Prejbisz, A. Januszewicz, A. Lutynska

CLINICA CHIMICA ACTA (2022)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.