Article
Cardiac & Cardiovascular Systems
Gregory D. Lewis, Kieran F. Docherty, Adriaan A. Voors, Alain Cohen-Solal, Marco Metra, David J. Whellan, Justin A. Ezekowitz, Piotr Ponikowski, Michael Bohm, John R. Teerlink, Stephen B. Heitner, Stuart Kupfer, Fady Malik, Lisa Meng, G. Michael Felker
Summary: Heart failure with reduced ejection fraction (HFrEF) is a serious condition characterized by exercise intolerance. The assessment methods for exercise capacity in HFrEF vary widely. Omecamtiv mecarbil, a novel cardiac myosin activator, has shown promising results in improving cardiac contractility and reducing heart failure events in HFrEF patients. The METEORIC-HF trial aims to evaluate the impact of omecamtiv mecarbil on various measures of functional capacity in HFrEF patients.
CIRCULATION-HEART FAILURE
(2022)
Review
Multidisciplinary Sciences
Alexis. K. K. Jones, Crystal Lihong Yan, Beatriz. P. Rivera P. Rodriquez, Sukhpreet Kaur, Sharon Andrade-Bucknor
Summary: Cardiac rehabilitation is a comprehensive program for managing cardiovascular risk factors, and wearable devices have emerged as potential tools for cardiovascular risk assessment. This scoping review analyzes the role of wearable devices in home-based cardiac rehabilitation (HBCR) and their impact on cardiovascular outcomes. The study found that HBCR using wearable devices can be a comparable alternative or adjunct to center-based cardiac rehabilitation.
Review
Cardiac & Cardiovascular Systems
Rod S. Taylor, Hasnain M. Dalal, Ann-Dorthe Zwisler
Summary: Cardiac rehabilitation is often overlooked in the treatment of heart failure. This review provides an update on the evidence, guidelines, and status of cardiac rehabilitation for heart failure patients. It argues that exercise-based rehabilitation is a crucial aspect of heart failure management, alongside medication and medical devices, as it improves patient outcomes, including their quality of life. To improve access and participation, healthcare services should offer heart failure patients a range of evidence-based rehabilitation options, including home-based programs with digital technology and traditional center-based programs, based on disease stage and patient preference.
EUROPEAN HEART JOURNAL
(2023)
Article
Multidisciplinary Sciences
Corinne Jola, Moa Sundstrom, Julia McLeod
Summary: Dance classes designed for people with Parkinson's have benefits in improving motor control abilities and mood. However, the quantitative evidence of these benefits is inconsistent. A mixed method approach was used to explore the effects of music in dance classes. The study found that music had a significant effect on improving gait before class, but not after class. The importance of music was further emphasized in qualitative data. Understanding how music and dance affect Parkinson's symptoms will help in the design of future interventions.
Article
Cardiac & Cardiovascular Systems
Mario Matta, Chiara Devecchi, Federica De Vecchi, Lorella Barbonaglia, Miriam Gravellone, Eraldo Occhetta, Francesco Rametta
Summary: The study showed that cardiac contractility modulation (CCM) can improve quality of life, symptoms, exercise tolerance, and left ventricular function in patients with symptomatic CHF and moderate-to-severe left ventricular systolic dysfunction. Additionally, CCM treatment also reduced hospitalizations in these patients.
MINERVA CARDIOLOGY AND ANGIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Stephan von Haehling, Michael Arzt, Wolfram Doehner, Frank Edelmann, Ruben Evertz, Nicole Ebner, Christoph Herrmann-Lingen, Tania Garfias Macedo, Michael Koziolek, Michel Noutsias, P. Christian Schulze, Rolf Wachter, Gerd Hasenfuss, Ulrich Laufs
Summary: The focus of large-scale trials in chronic heart failure has been on evaluating treatments in terms of hospitalizations and mortality, but improving exercise capacity and quality of life for patients with heart failure is also important. Current evidence shows limited effects of treatments on exercise capacity and quality of life, with further studies needed to better understand the effectiveness of these interventions.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Article
Respiratory System
Felipe V. C. Machado, Martijn A. Spruit, Miriam T. J. Groenen, Sarah Houben-Wilke, Paula P. van Melick, Nidia A. Hernandes, Annemie M. W. J. Schols, Fabio Pitta, Emiel F. M. Wouters, Frits M. E. Franssen
Summary: This study analyzed data from 469 COPD patients and found that over half of overweight and obese patients have low muscle mass when using age-gender-BMI-specific cut-offs. Low muscle mass is associated with worse functional outcomes in overweight and obese COPD patients.
RESPIRATORY RESEARCH
(2021)
Review
Cardiac & Cardiovascular Systems
Cal D. Molloy, Linda Long, Ify R. Mordi, Charlene Bridges, Viral A. Sagar, Edward J. Davies, Andrew J. S. Coats, Hasnain Dalal, Karen Rees, Sally J. Singh, Rod S. Taylor
Summary: Exercise-based cardiac rehabilitation (ExCR) has significant benefits for heart failure (HF) patients in reducing hospitalization rates and improving quality of life. Global healthcare systems should routinely recommend ExCR and offer different delivery modes for patients to choose.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Serlie Fatrin, Nduka C. Okwose, Kristian Bailey, Lazar Velicki, Dejana Popovic, Arsen Ristic, Petar M. Seferovic, Guy A. MacGowan, Djordje G. Jakovljevic
Summary: This study aimed to assess the relationship between functional capacity, hemodynamic response to exercise, and quality of life in chronic heart failure patients. It was found that peak O2 consumption is a significant determinant of quality of life in these patients, while exercise hemodynamic response is not significantly associated.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Critical Care Medicine
Nathalie Van Aerde, Philippe Meersseman, Yves Debaveye, Alexander Wilmer, Michael P. Casaer, Jan Gunst, Joost Wauters, Pieter J. Wouters, Kaatje Goetschalckx, Rik Gosselink, Greet Van den Berghe, Greet Hermans
Summary: The study evaluated aerobic exercise capacity in 5-year ICU survivors and found that they generally had lower exercise capacity, often with muscular limitation. Severity of organ failure during ICU stay was independently associated with impairments in exercise capacity.
INTENSIVE CARE MEDICINE
(2021)
Article
Integrative & Complementary Medicine
Bowei Mei, Lulu Yuan, Yankai Shu
Summary: This study aimed to assess the effects of Baduanjin exercise on the quality of life, cardiac function, and maximal oxygen consumption in patients with chronic heart failure. The results showed that Baduanjin exercise contributed to significant improvements in the quality of life, cardiac function, and maximal oxygen consumption for patients with chronic heart failure. Engaging in Baduanjin exercise 5-7 times per week was found to be more effective in improving quality of life compared to 3-4 times per week.
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2023)
Article
Cardiac & Cardiovascular Systems
Biykem Bozkurt, Gregg C. Fonarow, Lee R. Goldberg, Maya Guglin, Richard A. Josephson, Daniel E. Forman, Grace Lin, JoAnn Lindenfeld, Chris O'Connor, Gurusher Panjrath, Ileana L. Pina, Tina Shah, Shashank S. Sinha, Eugene Wolfel
Summary: Cardiac rehabilitation, which includes exercise training, risk factor modification, and outcomes assessment, is safe and beneficial for patients with HF. Despite its effectiveness and cost-efficiency, it is currently underused and should be prioritized as part of standard care for HF patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yuta Nagatomi, Tomomi Ide, Tae Higuchi, Tomoyuki Nezu, Takeo Fujino, Takeshi Tohyama, Takuya Nagata, Taiki Higo, Toru Hashimoto, Shouji Matsushima, Keisuke Shinohara, Tomiko Yokoyama, Aika Eguchi, Ayumi Ogusu, Masataka Ikeda, Yusuke Ishikawa, Fumika Yamashita, Shintaro Kinugawa, Hiroyuki Tsutsui
Summary: This study investigated the efficacy and safety of a comprehensive home-based cardiac rehabilitation programme that combines patient education, exercise guidance, and nutritional guidance using information and communication technology (ICT). The results showed that the programme improved exercise tolerance and lower extremity muscle strength in patients with heart failure and physical frailty.
Article
Oncology
Paul Saultier, Clothilde Vallet, Frederic Sotteau, Zeinab Hamidou, Jean-Claude Gentet, Vincent Barlogis, Catherine Curtillet, Arnauld Verschuur, Gabriel Revon-Riviere, Claire Galambrun, Herve Chambost, Pascal Auquier, Gerard Michel, Nicolas Andre
Summary: A study involving 80 children and adolescents with cancer showed that a physical activity program is safe and effective, improving exercise capacity and providing benefits for physical and psychological aspects, including flexibility, balance, strength, endurance, self-esteem, and quality of life.
Review
Pharmacology & Pharmacy
Jeanne Shan Yin Ong, Weiqin Lin, Tee Joo Yeo
Summary: Exercise-based cardiac rehabilitation (EBCR) is a well-established treatment modality for heart failure patients, offering numerous benefits and improving their quality of life. Despite historical barriers, alternative delivery methods such as telerehabilitation and focus on behavioral change are emerging. This review provides an overview of exercise training modalities, benefits, barriers, and future progress in EBCR.
CURRENT PHARMACEUTICAL DESIGN
(2023)
Review
Rehabilitation
Iura Gonzalez Nogueira Alves, Cassio Magalhaes da Silva e Silva, Bruno Prata Martinez, Rodrigo Santos de Queiroz, Mansueto Gomes-Neto
Summary: Neuromuscular electrical stimulation can improve exercise capacity and muscle strength in patients with chronic obstructive pulmonary disease (COPD), and combining it with conventional rehabilitation can further enhance exercise capacity. However, the improvement in disabilities and activity limitation in COPD with neuromuscular electrical stimulation is small, and the cost should be considered.
CLINICAL REHABILITATION
(2022)
Review
Critical Care Medicine
Alanna Ribeiro da Silva, Michelli Christina Magalhaes Novais, Mansueto Gomes Neto, Helena Franca Correia
Summary: The objective of this study was to identify predictors of extubation failure in neurocritical patients. A systematic review was performed, and cohort studies investigating predictors of extubation failure in adults were included. Fifteen predictors for extubation failure in neurocritical patients were identified, including low Glasgow Coma Scale score, female gender, mechanical ventilation time, and moderate or large secretion volume. Consideration of these factors is necessary to prevent extubation failure in clinical practice for neurocritical patients.
AUSTRALIAN CRITICAL CARE
(2023)
Review
Integrative & Complementary Medicine
Fabio Luciano Arcanjo, Jose Vicente Pereira Martins, Paulo Mote, Gustavo Leporace, Daniella Araujo de Oliveira, Camila Santana de Sousa, Micheli Bernadone Saquetto, Mansueto Gomes-Neto
Summary: This systematic review found that PNF training has positive effects on pain and disability in patients with low back pain. However, the quality of evidence for pain and disability outcomes is low to moderate.
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2022)
Review
Health Care Sciences & Services
Katna de Oliveira Almeida, Iura Gonzalez Nogueira Alves, Rodrigo Santos de Queiroz, Marcela Rodrigues de Castro, Vinicius Afonso Gomes, Fabiane Costa Santos Fontoura, Carlos Brites, Mansueto Gomes Neto
Summary: This study conducted a systematic review on the physical function, activities of daily living, and health-related quality of life in COVID-19 survivors. The findings indicate that COVID-19 survivors experience reduced levels of physical function, activities of daily living, and health-related quality of life. Furthermore, incomplete recovery in physical function and daily activities was observed within 1 to 6 months post-infection.
Article
Clinical Neurology
Jorge Motta Anjos, Mansueto Gomes Neto, Yuri de Araujo Tapparelli, Gayr Tse, Giuseppe Biondi-Zoccai, Yasmin de Souza Lima Bitar, Leonardo Roever, Andre Rodrigues Duraes
Summary: This study assessed the efficacy and safety of early mobilization after thrombolysis in patients with acute ischemic stroke. The results showed that early mobilization did not significantly reduce the risk of functional independence and other secondary outcomes within the study period.
JOURNAL OF NEUROLOGY
(2023)
Article
Rehabilitation
Janice de S. Guimaraes, Fabio L. Arcanjo, Gustavo Leporace, Leonardo F. Metsavaht, Cristiano Sena Conceicao, Marcus V. M. G. Moreno, Tulio E. Marcal Vieira, Carolina Cunha Moraes, Mansueto Gomes Neto
Summary: This study used systematic review and meta-analysis to identify various therapeutic interventions that seem to be effective in improving pain in patients with plantar fasciitis. Only extracorporeal shock wave therapy was found to be effective in improving pain in the medium and long term compared to the control group.
CLINICAL REHABILITATION
(2023)
Review
Pediatrics
Thalita Raysa de Lima Crispim, Mansueto Gomes Neto, Tafnes Rayane Lima Crispim, Renivaldo Batista Dias, Maria Deborah Monteiro de Albuquerque, Micheli Bernardone Saquetto, Paulo Andre Freire Magalhaes
Summary: Respiratory exercises in addition to conventional rehabilitation can significantly improve pulmonary function and inspiratory muscle strength in cerebral palsy patients. However, there is no consensus on the frequency, type, and intensity of respiratory exercises for children and adolescents with cerebral palsy.
WORLD JOURNAL OF PEDIATRICS
(2023)
Review
Sport Sciences
Fabricio Olinda de Souza Mesquita, Bruno Bavaresco Gambassi, Marcio de Oliveira Silva, Sergio Rodrigues Moreira, Victor Ribeiro Neves, Mansueto Gomes-Neto, Paulo Adriano Schwingel
Summary: This systematic review and meta-analysis examined the effects of high-intensity interval training (HIIT) on peak oxygen consumption (VO2 peak), blood pressure, cardiac autonomic modulation, and resting heart rate in hypertensive patients. The results demonstrated that despite the low quality of the evidence, HIIT was found to be superior to moderate-intensity continuous training (MICT) in improving VO2 peak in hypertensive patients. In addition, HIIT effectively improved VO2 peak, blood pressure, and resting heart rate compared to controls.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2023)
Review
Sport Sciences
Ingara Fernanda S. R. Schindler, Sarah S. Pontes, Mariana B. M. Bertoni, Grimaldo F. Junior, Balbino R. N. Junior, Fabio L. A. de Jesus, Mansueto G. Neto
Summary: This systematic review analyzed studies on reference values and protocols for measuring lower and upper limb isokinetic muscle strength in an untrained and noninjured healthy population. The results showed that muscle strength levels are influenced by age and sex, with agonist muscle groups being stronger than antagonist muscles and men generally having higher strength values than women. The identified reference values can be useful for professionals in evaluating diagnostic parameters of muscle deficiency.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2023)
Letter
Sport Sciences
Mansueto Gomes-Neto, Lino Sergio Rocha Conceicao, Caroline Oliveira Gois, Vitor Oliveira Carvalho
Review
Emergency Medicine
Mansueto Gomes Neto, Leonardo Fossati Metsavaht, Fabio Luciano Arcanjo, Janice de Souza Guimaraes, Cristiano Sena Conceicao, Eliane Celina Guadagnin, Vitor Oliveira Carvalho, Gustavo Leporace de Oliveira Lomelino Soares
Summary: This article provides an overview of systematic reviews on the prevalence, incidence, types, and locations of lower-extremity running-related musculoskeletal injuries. Recent studies have addressed these factors in different populations and countries. However, there is a lack of overview on the epidemiology of lower-extremity injuries in runners.
CURRENT EMERGENCY AND HOSPITAL MEDICINE REPORTS
(2023)
Review
Cardiac & Cardiovascular Systems
Alana Lalucha Andrade Guimaraes, Mansueto Gomes-Neto, Lino Sergio Rocha Conceicao, Micheli Bernardone Saquetto, Caroline Oliveira Gois, Vitor Oliveira Carvalho
Summary: Water-based exercise can improve the exercise capacity of patients with coronary artery disease, including peak oxygen consumption, exercise time, and muscle strength.
CARDIOVASCULAR THERAPEUTICS
(2023)
Review
Biophysics
Gustavo Leporace, Leonardo Metsavaht, Felipe F. Gonzalez, Fabio Arcanjo de Jesus, Mariana Machado, Eliane Celina Guadagnin, Mansueto Gomes-Neto
Summary: The aim of this systematic review was to synthesize the literature on the criterion validity and reliability of two-dimensional video analysis systems (2DVAS) for measuring angles during running, compared to three-dimensional motion analysis systems (3DMAS). The review found that the validity of 2DVAS compared to 3DMAS ranged from poor to excellent, with most parameters showing poor or moderate validity. However, the reliability of 2DVAS was generally good, especially for intra-rater reliability and inter-session reliability.
JOURNAL OF BIOMECHANICS
(2023)
Review
Rehabilitation
Andre Luiz Lisboa Cordeiro, Lucas Oliveira Soares, Mansueto Gomes-Neto, Jefferson Petto
Summary: This systematic review evaluated the evidence on inspiratory muscle training (IMT) in patients post cardiac surgery. IMT was found to have positive effects on maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), peak expiratory flow (PEF), tidal volume (TV), and length of hospital stay, but no impact on functional capacity.
ANNALS OF REHABILITATION MEDICINE-ARM
(2023)
Article
Medicine, General & Internal
Weris Lany Carapia do Nascimento, Diana Magnavita Moura, Katna De Oliveira Almeida, Mansueto Gomes-Neto, Sergio Fernandes de Oliveira Jezler, Iura Gonzalez Nogueira Alves
Summary: The study aimed to evaluate exercise capacity, lung and physical function among COVID-19 survivors, and explore the associations between lesion-level characteristics assessed by chest CT, probable sarcopenia, and percentage of diffusing capacity of the lung for carbon monoxide with clinical and functional variables. After COVID-19 infection, probable sarcopenia, reduced diffusing capacity of the lung for carbon monoxide, and decreased 6-minute walk distance were observed. Chest CT>50% was associated with longer hospital stay and lower diffusing capacity of the lung for carbon monoxide. Probable sarcopenia diagnosis was related to worse predicted 6-minute walk distance, absolute 6-minute walk distance (m), diffusing capacity of the lung for carbon monoxide, and total lung capacity percentage. The findings suggest that COVID-19 survivors commonly experience muscle disability and lung dysfunction, and prolonged hospitalization may lead to worsened muscle force and diffusing capacity of the lung for carbon monoxide. Additionally, the probable diagnosis of sarcopenia may impact walking distance. Long-term follow-up and rehabilitation programs are necessary for these patients.
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
(2023)
Article
Rehabilitation
Rose Goonan, Edward Mohandoss, Celia Marston, Jaqueline Kay, Anurika Priyanjali De Silva, Andrea B. Maier, Esmee Reijnierse, Marlena Klaic
Summary: This study evaluated the physical and functional outcomes of the 'Ending Pyjama Paralysis' intervention in geriatric rehabilitation patients. The results showed that this intervention did not lead to additional functional and physical benefits in this setting.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Sinikka Kilpikoski, Arja H. Hakkinen, Jussi P. Repo, Kati Kyrola, Juhani Multanen, Markku Kankaanpaa, Aki Vainionpaa, Esa-Pekka Takala, Hannu Kautiainen, Jari Ylinen
Summary: This study aimed to compare the effectiveness of a McKenzie Method intervention with guideline-based patient education in patients with sciatica. The results showed that multiple sessions of McKenzie-based back exercises combined with a patient's educational book had similar long-term effects to guideline-based advice. However, the small sample size and confounding factors limited the power of these results.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Margot W. M. de Waal, Michael Jansen, Loes M. Bakker, Arno J. Doornebosch, Elizabeth M. Wattel, Dennis Visser, Ewout B. Smit
Summary: The Utrecht Scale for Evaluation of Rehabilitation has been shown to be effective in evaluating physical and cognitive functioning in geriatric rehabilitation. A minimal important change of 14.5 points has been established for physical functioning.
CLINICAL REHABILITATION
(2024)
