Article
Clinical Neurology
Gen Li, Pei Huang, Shishuang Cui, Yachao He, Yuyan Tan, Shengdi Chen
Summary: Long-term Tai Chi training in patients with Parkinson's disease showed maintenance of improvement in motor and non-motor symptoms, reducing the need for increasing antiparkinsonian therapies. The annual increase in levodopa equivalent daily dosage was significantly lower in the Tai Chi group, indicating the benefits of Tai Chi training on PD symptoms and complications.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Giuseppe Dattilo, Giulia Laterra, Roberto Licordari, Francesca Parisi, Lorenzo Pistelli, Luigi Colarusso, Luca Zappia, Vittoria Vaccaro, Elisabetta Demurtas, Marta Allegra, Pasquale Crea, Gianluca Di Bella, Salvatore Santo Signorelli, Nadia Aspromonte, Egidio Imbalzano, Michele Correale
Summary: This study evaluated the effects of Sacubitril/Valsartan treatment in patients with HFrEF for a period of 5 years. The results showed that the treatment not only improved patient outcomes after 1 year, but continued to show significant improvements at 5 years, with profound clinical implications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Charles Hebert, Jay M. Behel, Gian Pal, Ravi Kasi, Katie Kompoliti
Summary: Multidisciplinary inpatient rehabilitation can improve the function, depression, anxiety, and somatic symptoms of FMD patients, but the sustained improvement after one year is minimal.
PARKINSONISM & RELATED DISORDERS
(2021)
Article
Medicine, General & Internal
Thibaut Waeckel, Khelifa Ait Said, Benjamin Menahem, Anais Briant, Arnaud Doerfler, Arnaud Alves, Xavier Tillou
Summary: A 6-year follow-up study of 83 women who underwent bariatric surgery showed that the procedure had long-term effects in improving stress urinary incontinence (SUI) and overactive bladder disorders (OAB), leading to a positive impact on quality of life.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Environmental Sciences
Jun Yang, Mohammad Javad Zare Sakhvidi, Kees de Hoogh, Danielle Vienneau, Jack Siemiatyck, Marie Zins, Marcel Goldberg, Jie Chen, Emeline Lequy, Benedicte Jacquemin
Summary: The study on a large population-based French cohort found a significant association between long-term exposure to black carbon (BC) and mortality, with higher risk of all-cause and cardiovascular mortality. The impact of BC was more significant among never-smokers and individuals with lower fruit/vegetable intake.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Oncology
Geert Spierenburg, Peter Grimison, Christine Chevreau, Silvia Stacchiotti, Sophie Piperno-Neumann, Axel Le Cesne, Virginia Ferraresi, Antoine Italiano, Florence Duffaud, Nicolas Penel, Severine Metzger, Sylvie Chabaud, Lizz van der Heijden, David Perol, Michiel A. J. van de Sande, Jean-Yves Blay, Hans Gelderblom
Summary: Long-term analysis of nilotinib for advanced D-TGCT showed approximately half of patients experienced progression and required additional treatment after 8.5 years, while some patients maintained disease control after limited treatment duration.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Critical Care Medicine
Abebaw M. Yohannes, Sheila Dryden, Richard Casaburi, Nicola A. Hanania
Summary: An effective 8-week PR program provides sustained improvement in anxiety and quality of life for COPD patients over a 2-year period, but short-term improvements in dyspnea, depression, and stress symptoms at 8 weeks were not maintained at 2 years.
Article
Medicine, General & Internal
Maria Addolorata Bonifacio, Daniele Roselli, Claudia Pia Schifone, Alessandra Ricco, Angelantonio Vitucci, Lara Aprile, Maria Addolorata Mariggio, Prudenza Ranieri
Summary: Damage to the endothelium leads to the release of von Willebrand factor (VWF) and its binding to platelets, which are recruited to sites of vascular injury. Autoantibodies targeting ADAMTS13 cause an increase in VWF, particularly in its ultra-large multimers, leading to platelet aggregation, thrombus formation, and microangiopathic hemolytic anemia. This immune-mediated condition, known as immune-mediated thrombotic thrombocytopenic purpura (iTTP), has a high morbidity and relapse rate.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Carter J. Boyd, Ara A. Salibian, Jonathan M. Bekisz, Deborah M. Axelrod, Amber A. Guth, Richard L. Shapiro, Freya R. Schnabel, Nolan S. Karp, Mihye Choi
Summary: This study analyzed the breast cancer recurrence in patients who underwent therapeutic nipple-sparing mastectomy with a median follow-up of 10 years. The results showed low overall recurrence rates, but close surveillance is still necessary to promptly identify potential recurrence.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Clinical Neurology
M. Nassif, M. E. Annink, H. Yang, T. C. D. Rettig, Y. B. W. E. M. Roos, R. B. A. van den Brink, J. G. P. Tijssen, B. J. M. Mulder, R. J. de Winter, B. J. Bouma
Summary: The study found a relatively high incidence of recurrent stroke/TIA during long-term follow-up of young ESUS patients, while the incidence of new-onset clinical AF was relatively low and may not play a significant role in the pathophysiology of first-ever and recurrent stroke/TIA in these patients.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Article
Endocrinology & Metabolism
Tibor V. Varga, Tianwei Xu, Mika Kivimaki, Amar J. Mehta, Reiner Rugulies, Naja H. Rod
Summary: The study found that individuals with high organizational justice had more favorable long-term cardiometabolic biomarker patterns compared to those with low organizational justice. This suggests that organizational justice may contribute to the lower risk of chronic diseases by influencing metabolic trajectories over time.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Medicine, General & Internal
Nardia-Rose Klem, Anne Smith, Peter O'Sullivan, Michelle M. Dowsey, Robert Schutze, Peter Kent, Peter F. M. Choong, Samantha Bunzli
Summary: The study found that patient satisfaction is a multifactorial construct that is potentially modifiable over time. Most patients had stable satisfaction levels 3-4 years post-TKR, with some exceptions. The findings confirmed the meaning of satisfaction and factors influencing satisfaction, while also highlighting the importance of beliefs related to age and persistent knee symptoms in satisfaction.
Article
Radiology, Nuclear Medicine & Medical Imaging
Peng Dong, Deng-Ke Teng, Guo-Qing Sui, Yuan-Qiang Lin, Qiang Luo, Qi-Meihui Wang, He-Qun Li, Hui Wang
Summary: This study evaluated the long-term efficacy of microwave ablation (MWA) for low-risk multifocal papillary thyroid microcarcinoma (MPTMC) and provided evidence-based medicine for the revision of clinical guidelines. The results showed that MWA is safe and effective for treating MPTMC, and it can serve as an alternative option for patients who refuse surgery or active surveillance.
EUROPEAN RADIOLOGY
(2023)
Article
Oncology
Agnes Dumas, Karen Milcent, Nicolas Bougas, Daniel Bejarano-Quisoboni, Chiraz El Fayech, Helene Charreire, Odile Oberlin, Catherine Patte, Julie Allard, Eric Thebault, Amel Boumaraf, Amel Belhout, Vu-Bezin Giao, Vincent Souchard, Angela Jackson, Rodrigue Allodji, Dominique Valteau-Couanet, Christelle Dufour, Gilles Vassal, Nadia Haddy, Florent De Vathaire, Brice Fresneau
Summary: The study found that patients who received combined chemotherapy and radiotherapy, had bone sarcoma, central nervous system primitive tumor, or underwent autologous hematopoietic cell transplant were more likely to attend long-term follow-up visits. Additionally, factors such as health status, medical expenses, social status, and distance from the follow-up center also influenced attendance.
Article
Obstetrics & Gynecology
Ninna Hinchely Ebdrup, Lena Hohwu, Bjorn Bay, Carsten Obel, Ulla Breth Knudsen, Ulrik Schioler Kesmodel
Summary: This study aimed to investigate the long-term growth of children born following fertility treatment up to adulthood and found that children born to parents who received fertility treatment or to subfertile parents had comparable growth in weight and height to children conceived spontaneously by fertile parents.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Rehabilitation
Nilla Andersson, Jan Lexell, Christina Brogardh
Article
Clinical Neurology
Sophie Jorgensen, Linn Hedgren, Anna Sundelin, Jan Lexell
Summary: This study assessed life satisfaction among older adults with long-term SCI and found that having a partner and being vocationally active were associated with greater overall life satisfaction. Participants with AIS D injuries were less satisfied with their somatic health.
JOURNAL OF SPINAL CORD MEDICINE
(2021)
Article
Rehabilitation
Maria Nolvi, Christina Brogardh, Lars Jacobsson, Jan Lexell
Article
Rehabilitation
Catharina Sjodahl Hammarlund, Jan Lexell, Christina Brogardh
Summary: This study describes the experiences of individuals with late effects of paralytic polio, including the strategies developed to adapt to the new situation. Strategies such as optimistic thinking, blending in, trusting one's abilities, and managing others' preconceptions were identified. While some strategies continued to be effective in dealing with late effects of polio, behaviors like overachieving, disregarding pain, and weariness were no longer helpful.
DISABILITY AND REHABILITATION
(2021)
Article
Clinical Neurology
Lars Jacobsson, Jan Lexell
ACTA NEUROLOGICA SCANDINAVICA
(2020)
Article
Rehabilitation
Elisabeth Ekstrand, Jan Lexell, Christina Brogardh
Article
Sport Sciences
Kristina Fagher, Orjan Dahlstrom, Jenny Jacobsson, Toomas Timpka, Jan Lexell
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2020)
Article
Rehabilitation
Christina Brogardh, Jan Lexell, Albert Westergren
Summary: The study found that the Walk-12 scale in persons with late effects of polio has some psychometric issues, including multidimensionality, local dependency, and compromised targeting. While reliability was high, further development and improvement of the scale are needed to enhance its targeting.
Article
Sport Sciences
Richard Weiler, Cheri Blauwet, David Clarke, Kristine Dalton, Wayne Derman, Kristina Fagher, Vincent Gouttebarge, James Kissick, Kenneth Lee, Jan Lexell, Peter Van de Vliet, Evert Verhagen, Nick Webborn, Osman Hassan Ahmed
Summary: Concussion is common in para athletes, but research in this area is lacking. The CIPS expert group was established to address this issue and improve concussion care for para athletes. Specific issues for para athletes were discussed within the framework of the 2017 International Concussion in Sport consensus statement.
BRITISH JOURNAL OF SPORTS MEDICINE
(2021)
Article
Neurosciences
Jan Lexell, Gustav Loven, Kristina Fagher
Summary: The study found that the incidence proportion of sports-related concussion (SRC) among elite Para athletes was 9.3%, with an incidence rate of 0.5 SRC/1000 hours. Athletes with vision impairment and female athletes reported a significantly higher proportion of SRC, and the majority of injuries occurred during sport-specific training.
Editorial Material
Sport Sciences
Richard Weiler, Cheri Blauwet, David Clarke, Kristine Dalton, Wayne Derman, Kristina Fagher, Vincent Gouttebarge, James Kissick, Kenneth Lee, Jan Lexell, Peter Van de Vliet, Evert Verhagen, Nick Webborn, Adam Virgile, Osman Hassan Ahmed
BRITISH JOURNAL OF SPORTS MEDICINE
(2022)
Article
Clinical Neurology
Mattias Hill, Sophie Jorgensen, Gunnar Engstrom, Margaretha Persson, Per Wollmer, Jan Lexell
Summary: This study describes the functional and structural impairments of the pulmonary system in middle-aged individuals with cervical and upper thoracic spinal cord injuries (SCI), and compares the findings to the general population. The research found that middle-aged individuals with long-term SCI can have significant pulmonary functional impairments, while the structural impairments do not differ considerably from the general population. The neurological level of injury (NLI) was found to be related to some of the functional and structural impairments.
JOURNAL OF SPINAL CORD MEDICINE
(2023)
Article
Environmental Sciences
Maria Nolvi, Anna Forsberg, Christina Brogardh, Lars Jacobsson, Jan Lexell
Summary: This study explored the meaning of Sense of Coherence (SOC) among persons living with Late Effects of Polio (LEoP), finding that SOC in these individuals exists in a state of motion and a state of being. Understanding SOC as both a state of motion and state being is crucial for rehabilitation professionals providing self-management support to persons living with LEoP.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Christina Brogardh, Jan Lexell, Catharina Sjodahl Hammarlund
Summary: Reduced walking ability is common in persons with late effects of polio (LEoP). This study used a mixed-methods design to explore the perceived walking limitations and their influence on daily life in individuals with LEoP. The results showed that standing or walking, walking speed and distance were moderately to extremely limited in the majority of participants, which affected concentration, effort, and gait quality. These walking limitations intruded on many everyday activities and had a negative impact on social participation. Various strategies, such as using aids, walking carefully, and avoiding risky activities, were adopted to increase safety when walking and reduce the risk of falls.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Editorial Material
Sport Sciences
Phoebe Runciman, Cheri Blauwet, James Kissick, Jan Lexell, Martin Schwellnus, Nick Webborn, Wayne Derman
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Rehabilitation
Rose Goonan, Edward Mohandoss, Celia Marston, Jaqueline Kay, Anurika Priyanjali De Silva, Andrea B. Maier, Esmee Reijnierse, Marlena Klaic
Summary: This study evaluated the physical and functional outcomes of the 'Ending Pyjama Paralysis' intervention in geriatric rehabilitation patients. The results showed that this intervention did not lead to additional functional and physical benefits in this setting.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Sinikka Kilpikoski, Arja H. Hakkinen, Jussi P. Repo, Kati Kyrola, Juhani Multanen, Markku Kankaanpaa, Aki Vainionpaa, Esa-Pekka Takala, Hannu Kautiainen, Jari Ylinen
Summary: This study aimed to compare the effectiveness of a McKenzie Method intervention with guideline-based patient education in patients with sciatica. The results showed that multiple sessions of McKenzie-based back exercises combined with a patient's educational book had similar long-term effects to guideline-based advice. However, the small sample size and confounding factors limited the power of these results.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Margot W. M. de Waal, Michael Jansen, Loes M. Bakker, Arno J. Doornebosch, Elizabeth M. Wattel, Dennis Visser, Ewout B. Smit
Summary: The Utrecht Scale for Evaluation of Rehabilitation has been shown to be effective in evaluating physical and cognitive functioning in geriatric rehabilitation. A minimal important change of 14.5 points has been established for physical functioning.
CLINICAL REHABILITATION
(2024)