Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects
Authors
Keywords
Nitrite, Mean Arterial Pressure, Pulmonary Arterial Hypertension, Maximum Tolerate Dose, Sodium Nitrite
Journal
CLINICAL PHARMACOKINETICS
Volume 54, Issue 3, Pages 261-272
Publisher
Springer Nature
Online
2014-12-02
DOI
10.1007/s40262-014-0201-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite
- (2013) Abdul R Maher et al. BRITISH JOURNAL OF PHARMACOLOGY
- Safety and pharmacokinetics of sodium nitrite in patients with subarachnoid hemorrhage: a Phase IIA study
- (2013) Edward H. Oldfield et al. JOURNAL OF NEUROSURGERY
- Myoglobin’s novel role in nitrite-induced hypoxic vasodilation
- (2013) Ulrike B. Hendgen-Cotta et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Nitrite Signaling in Pulmonary Hypertension: Mechanisms of Bioactivation, Signaling, and Therapeutics
- (2012) Marta Bueno et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxygen Regulates Tissue Nitrite Metabolism
- (2011) Erin Curtis et al. ANTIOXIDANTS & REDOX SIGNALING
- Safety and Feasibility of Long-term Intravenous Sodium Nitrite Infusion in Healthy Volunteers
- (2011) Ryszard M. Pluta et al. PLoS One
- Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery
- (2010) David C. Pryde et al. JOURNAL OF MEDICINAL CHEMISTRY
- Low-dose sodium nitrite vasodilates hypoxic human pulmonary vasculature by a means that is not dependent on a simultaneous elevation in plasma nitrite
- (2009) Thomas E. Ingram et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways
- (2009) AG Pinder et al. BRITISH JOURNAL OF PHARMACOLOGY
- Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation
- (2009) Brian S. Zuckerbraun et al. CIRCULATION
- Characterization of the Magnitude and Mechanism of Aldehyde Oxidase-mediated Nitric Oxide Production from Nitrite
- (2009) Haitao Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bioavailability of sodium nitrite from an aqueous solution in healthy adults
- (2009) Claudine C. Hunault et al. TOXICOLOGY LETTERS
- Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study
- (2008) A. Kyle Mack et al. BRITISH JOURNAL OF HAEMATOLOGY
- Hypoxic Modulation of Exogenous Nitrite-Induced Vasodilation in Humans
- (2008) Abdul R. Maher et al. CIRCULATION
- Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury
- (2008) U. B. Hendgen-Cotta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now