A Novel Double-Tracer Technique to Characterize Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]Tofogliflozin After Oral Administration and Concomitant Intravenous Microdose Administration of [13C]Tofogliflozin in Humans

Inhibition of Renal Glucose Reabsorption: A Novel Strategy for Achieving Glucose Control in Type 2 Diabetes Mellitus

(2013) Muhammad Abdul-Ghani et al.   Endocrine Practice

Calculation and Mitigation of Isotopic Interferences in Liquid Chromatography–Mass Spectrometry/Mass Spectrometry Assays and Its Application in Supporting Microdose Absolute Bioavailability Studies

(2012) Huidong Gu et al.   ANALYTICAL CHEMISTRY

Novel strategies for microdose studies using non-radiolabeled compounds

(2011) Kazuya Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Modeling and predicting drug pharmacokinetics in patients with renal impairment

(2011) Karen Rowland Yeo et al.   Expert Review of Clinical Pharmacology

Glucose transport by human renal Na+/d-glucose cotransporters SGLT1 and SGLT2

(2010) Charles S. Hummel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Microdose Study of 14C-Acetaminophen With Accelerator Mass Spectrometry to Examine Pharmacokinetics of Parent Drug and Metabolites in Healthy Subjects

(2010) Z Tozuka et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacokinetics of fexofenadine: Evaluation of a microdose and assessment of absolute oral bioavailability

(2010) Graham Lappin et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

SGLT2 inhibition — a novel strategy for diabetes treatment

(2010) Edward C. Chao et al.   NATURE REVIEWS DRUG DISCOVERY

Human radiolabeled mass balance studies: objectives, utilities and limitations

(2009) Natalia Penner et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Effective Use of Microdosing and Positron Emission Tomography (PET) Studies on New Drug Discovery and Development

(2009) Yuichi Sugiyama   Drug Metabolism and Pharmacokinetics

Renal sodium–glucose transport: role in diabetes mellitus and potential clinical implications

(2009) George L. Bakris et al.   KIDNEY INTERNATIONAL

Assessment of the Impact of Renal Impairment on Systemic Exposure of New Molecular Entities: Evaluation of Recent New Drug Applications

(2008) Y Zhang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The utility of microdosing over the past 5 years

(2008) Graham Lappin et al.   Expert Opinion on Drug Metabolism & Toxicology

Microdosing Assessment to Evaluate Pharmacokinetics and Drug Metabolism in Rats Using Liquid Chromatography-Tandem Mass Spectrometry

(2008) Jinsong Ni et al.   PHARMACEUTICAL RESEARCH