Population Pharmacokinetics and Pharmacogenetics of Everolimus in Renal Transplant Patients

A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients

(2011) L. Elens et al.   CLINICAL CHEMISTRY

Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial

(2011) Klemens Budde et al.   LANCET

CYP3A5 Genotype Does Not Influence Everolimus In Vitro Metabolism and Clinical Pharmacokinetics in Renal Transplant Recipients

(2011) Nicolas Picard et al.   TRANSPLANTATION

De novo Therapy with Everolimus, Low-Dose Ciclosporine A, Basiliximab and Steroid Elimination in Pediatric Kidney Transplantation

(2010) L. Pape et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding

(2010) Monica A. Istrate et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part II

(2010) Christine E. Staatz et al.   CLINICAL PHARMACOKINETICS

Explaining variability in ciclosporin exposure in adult kidney transplant recipients

(2010) Rogier R. Press et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Population Pharmacokinetics and Pharmacogenetics of Mycophenolic Acid Following Administration of Mycophenolate Mofetil in De Novo Pediatric Renal-Transplant Patients

(2010) Wei Zhao et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The unique complexity of the CYP3A4 upstream region suggests a nongenetic explanation of its expression variability

(2010) Huan Qiu et al.   Pharmacogenetics and Genomics

Liquid Chromatography-Tandem Mass Spectrometry Outperforms Fluorescence Polarization Immunoassay in Monitoring Everolimus Therapy in Renal Transplantation

(2010) Dirk Jan A R Moes et al.   THERAPEUTIC DRUG MONITORING

Optimal Everolimus Concentration Is Associated With Risk Reduction for Acute Rejection in De Novo Renal Transplant Recipients

(2010) Laurence Chan et al.   TRANSPLANTATION

Gene Expression of P-glycoprotein and Cytochrome P450 3A4 in Peripheral Blood Mononuclear Cells and Correlation With Expression in Liver

(2010) C.-Y. Lee et al.   TRANSPLANTATION PROCEEDINGS

Low-Dose Calcineurin Inhibitor Regimen Combined With Mammalian Target of Rapamycin Inhibitors Preserves Kidney Functions in Renal Transplant Recipients Without Allograft Nephropathy

(2010) S. Kacar et al.   TRANSPLANTATION PROCEEDINGS

Calcineurin Inhibitor-Free Immunosuppression in Pediatric Renal Transplantation

(2010) Britta Höcker et al.   PEDIATRIC DRUGS

Tacrolimus Population Pharmacokinetic-Pharmacogenetic Analysis and Bayesian Estimation in Renal Transplant Recipients

(2009) Khaled Benkali et al.   CLINICAL PHARMACOKINETICS

Population Pharmacokinetics and Pharmacogenetics of Tacrolimus in De Novo Pediatric Kidney Transplant Recipients

(2009) W Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The role of CYP3A5 genotypes in dose requirements of tacrolimus and everolimus after heart transplantation

(2009) Daniela Kniepeiss et al.   CLINICAL TRANSPLANTATION

Pharmacogenetics and population pharmacokinetics: impact of the design on three tests using the SAEM algorithm

(2009) Julie Bertrand et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression

(2009) V. Lamba et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms

(2009) Samuel Fanta et al.   Pharmacogenetics and Genomics

Explaining Variability in Tacrolimus Pharmacokinetics to Optimize Early Exposure in Adult Kidney Transplant Recipients

(2009) Rogier R Press et al.   THERAPEUTIC DRUG MONITORING

Robust, High-Throughput LC-MS/MS Method for Therapeutic Drug Monitoring of Cyclosporine, Tacrolimus, Everolimus, and Sirolimus in Whole Blood

(2009) Remco A Koster et al.   THERAPEUTIC DRUG MONITORING

Minimization of Maintenance Immunosuppression Early After Renal Transplantation: An Interim Analysis

(2009) Frederike J. Bemelman et al.   TRANSPLANTATION