Article
Agriculture, Dairy & Animal Science
Joanna Bonecka, Michal Skibniewski, Pawel Zep, Malgorzata Domino
Summary: Osteoarthritis (OA) is a common condition in cats characterized by progressive degenerative joint disease. This study aimed to investigate the occurrence of clinical symptoms and radiological signs of knee joint OA in cats of different body condition scores (BCS) and found that severe OA appears with similar frequency in underweight, normal-weight, and overweight cats. Therefore, a detailed history should be taken by veterinarians to identify non-specific clinical symptoms of OA, regardless of the cat's body weight. The prevalence of clinical symptoms and radiographic signs is different in overweight cats.
Article
Virology
Julia Gsenger, Thomas Bruckner, Clara Marlene Ihling, Rebecca Marie Rehbein, Sarah Valerie Schnee, Johannes Hoos, Britta Manuel, Johannes Pfeil, Paul Schnitzler, Julia Tabatabai
Summary: RSV is the major cause of acute respiratory tract infection in infants and young children. A standardized and simple-to-use disease severity score called RSV-CLASS was created and validated based on data from over 700 RSV-infected children. The score includes four items (cough, tachypnea, rales, and wheezing) and can accurately assess the severity of RSV infection.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Review
Health Care Sciences & Services
Ryota Nakano, Hideyuki Shiomi, Aoi Fujiwara, Kohei Yoshihara, Ryota Yoshioka, Shoki Kawata, Shogo Ota, Yukihisa Yuri, Tomoyuki Takashima, Nobuhiro Aizawa, Naoto Ikeda, Takashi Nishimura, Hirayuki Enomoto, Hiroko Iijima
Summary: The use of immune checkpoint inhibitors has increased, but the management of immune-related adverse events has become a problem. ICI-related pancreatitis and cholangitis are relatively rare and require further clarification of their pathogenesis. Endoscopy plays an increasingly important role in the diagnosis and treatment of inflammatory pancreatic and biliary duct diseases.
Article
Medicine, General & Internal
Moritz M. Innmann, Andre Lunz, Larissa Froehlich, Thomas Bruckner, Christian Merle, Tobias Reiner, Marcus Schiltenwolf
Summary: This study aimed to determine the correlation between patient-reported clinical function, pain, knee range of motion, and radiographic features in patients with knee osteoarthritis. It found that pain levels and knee joint condition were weakly correlated with the severity of the disease, and clinical function was associated with pain and radiographic features.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Gabriela Alejandra Bou, Rocio Garcia-Santibanez, Alexander Jordan Castilho, Spencer Kristian Hutto
Summary: This study aimed to investigate the long-term clinical evolution of neurosarcoidosis affecting the cauda equina, its response to treatment, and clinical and radiographic outcomes. The study found that cauda equina involvement in neurosarcoidosis is characterized by chronic, delayed presentations, nodular enhancement on MRI, poor response to corticosteroids, and substantial neurologic disability. Second-line agents such as methotrexate/infliximab, methotrexate, and azathioprine showed improvement in some patients.
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION
(2022)
Article
Clinical Neurology
Pressley A. Chakales, Max C. Herman, Ling Chen Chien, Spencer K. Hutto
Summary: This study aimed to investigate the clinical and radiographic features of pachymeningeal involvement in neurosarcoidosis and its response to treatment over time. The results showed that pachymeningitis in neurosarcoidosis often presents with symptoms such as headaches, visual dysfunction, and seizures. It primarily affects the falx cerebri, anterior and middle cranial fossae, and tentorium cerebelli. Treatment with steroids initially improves symptoms, but most patients require steroid-sparing immunosuppressants. Relapses may occur, but the prognosis for recovery is good.
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION
(2022)
Article
Rheumatology
Pamela Diaz, Joy Feld, Iris Eshed, Lihi Eder
Summary: Prevalence of inflammatory and structural lesions in patients with psoriatic disease can be assessed using whole spine MRI, but their correlation with clinical features and axSpA classification criteria is poor.
Article
Infectious Diseases
Megan Bardsley, Roger A. Morbey, Helen E. Hughes, Charles R. Beck, Conall H. Watson, Hongxin Zhao, Joanna Ellis, Gillian E. Smith, Alex J. Elliot
Summary: This study describes the epidemiological changes of respiratory syncytial virus (RSV) among children under 5 years old in England since 2020. The study found that RSV activity was significantly reduced during the winter of 2020-21, but an unprecedented summer surge occurred in 2021. Rating: 9/10.
LANCET INFECTIOUS DISEASES
(2023)
Article
Immunology
Lisa Staadegaard, Saverio Caini, Sonam Wangchuk, Binay Thapa, Walquiria Aparecida Ferreira de Almeida, Felipe Cotrim de Carvalho, Richard Njouom, Rodrigo A. Fasce, Patricia Bustos, Jan Kyncl, Ludmila Novakova, Alfredo Bruno Caicedo, Domenica Joseth de Mora Coloma, Adam Meijer, Mariette Hooiveld, Sue Huang, Tim Wood, Raquel Guiomar, Ana Paula Rodrigues, Daria Danilenko, Kirill Stolyarov, Vernon Jian Ming Lee, Li Wei Ang, Cheryl Cohen, Jocelyn Moyes, Amparo Larrauri, Concepcion Delgado-Sanz, Mai Quynh Le, Phuong Vu Mai Hoang, Clarisse Demont, Mathieu Bangert, Jojanneke van Summeren, Michel Duckers, John Paget
Summary: The study initiated the Global Epidemiology of RSV in Hospitalized and Community care (GERi) to better understand the global epidemiology of RSV. Data from 44 countries showed a high number of RSV cases among <1-year-olds, indicating a need for prevention efforts in this group.
OPEN FORUM INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Markus Neubauer, Lukas Moser, Johannes Neugebauer, Marcus Raudner, Barbara Wondrasch, Magdalena Fuehrer, Robert Emprechtinger, Dietmar Dammerer, Richard Ljuhar, Christoph Salzlechner, Stefan Nehrer
Summary: Comparisons between AI-aided and AI-unaided diagnoses showed that AI-aided diagnoses had a stronger correlation with clinical severity. Specifically, AI-aided diagnoses had higher associations with overall KL score and KOOS. This suggests that AI-guided systems can improve the ratings of knee radiographs and show a stronger association with clinical severity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Robert W. Elrod, Christopher E. Pelt, J. Bohannan Mason, Alexander J. Volkmar, Gregory G. Polkowksi, Rogelio A. Coronado, J. Ryan Martin
Summary: This study compares the incidence of novel radiographic findings between patients with aseptic loosening and patients with well-fixed implants. It finds that patients with aseptic loosening are more likely to have anterior heterotopic bone formation and medial or lateral cyst formation.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Immunology
Marissa K. Hetrich, Jennifer Oliva, Kimberli Wanionek, Maria Deloria Knoll, Matthew Lamore, Ignacio Esteban, Vic Veguilla, Fatimah S. Dawood, Ruth A. Karron
Summary: During the COVID-19 pandemic, the circulation of human parainfluenza type 3 (HPIV-3) and respiratory syncytial virus (RSV) increased, especially in households with young children aged 0-4 years attending childcare or preschool. These findings highlight the importance of understanding the epidemiology and risk factors of other respiratory viruses during the pandemic.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Pediatrics
Kara G. Gill
Summary: Radiographs performed in neonates can provide important clues to underlying diagnoses, especially when closely examining osseous structures. Certain skeletal anomalies may hint at more complex entities, requiring further evaluation and diagnosis.
PEDIATRIC RADIOLOGY
(2022)
Article
Medicine, General & Internal
Jelena Jankovic, Branislava Milenkovic, Ognjan Skrobic, Nenad Ivanovic, Natasa Djurdjevic, Ivana Buha, Aleksandar Jandric, Nikola Colic, Jelena Milin-Lazovic
Summary: Three subtypes of achalasia have been defined using esophageal manometry, but symptoms are experienced differently among men and women regardless of subtype. All subtypes can have an impact on respiratory symptoms and lung complications, and the aim of this research was to analyze these differences. The study found that respiratory symptoms were reported in 48% of patients, and all of them had gastrointestinal symptoms. The most common subtype was subtype 2, and 57.5% of patients with achalasia had some pulmonary abnormalities.
Review
Medicine, General & Internal
Fatemeh Ezzati, Parham Pezeshk
Summary: Clinical presentation can be challenging in patients with arthralgia, and imaging plays a crucial role in making diagnosis or narrowing the differential diagnosis. Hand radiography is a commonly used imaging modality that provides crucial information about the pattern and pathology of affected joints. Familiarity with the imaging findings of different rheumatic diseases is important for radiologists and rheumatologists to make early diagnosis and initiate treatment.
Article
Immunology
Denver Niles, Juri Boguniewicz, Omar Shakeel, Judith Margolin, Daniel Chelius, Meenal Gupta, David Paul, Katherine Y. King, J. Chase McNeil
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2019)
Article
Microbiology
Denver T. Niles, Dona S. S. Wijetunge, Debra L. Palazzi, Ila R. Singh, Paula A. Revell
JOURNAL OF CLINICAL MICROBIOLOGY
(2020)
Article
Immunology
Denver T. Niles, Paula A. Revell, Daniel Ruderfer, Lucila Marquez, J. Chase McNeil, Debra L. Palazzi
Summary: Plasma metagenomic next-generation sequencing (mNGS) has the potential to detect multiple organisms with a single test. The study found that mNGS testing had the highest clinical impact in immunocompromised patients with well-defined deep-seated infections. Further research is needed to evaluate the full range of clinical scenarios for which mNGS testing is beneficial.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Review
Infectious Diseases
Denver T. Niles, Rose A. Lee, Gabriella S. Lamb, Fatima Al Dhaheri, Juri Boguniewicz
Summary: Plasma cell-free metagenomic next-generation sequencing (cf-mNGS) is a non-invasive method that can identify a wide range of pathogens. However, its accuracy compared to conventional microbiologic testing remains uncertain. A systematic review and meta-analysis of published studies on hospitalized patients showed that cf-mNGS had a pooled positive percent agreement (PPA) of 67% and a pooled negative percent agreement (NPA) of 70%. These results indicate that cf-mNGS provides limited evidence for ruling in or out the presence of infection.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2023)
Meeting Abstract
Clinical Neurology
Mohammad Mortazavi, Katelyn Paulsen, Tyler R. Marx, Monica Pita Other, Luke Muratalla Maes, Arvind Balaji, Leslie Streeter, Brett Dusenberry
Meeting Abstract
Clinical Neurology
Mohammad Mortazavi, Tyler R. Marx, Leslie Streeter, Arvind Balaji, Brett Dusenberry, Luke Muratalla Maes, Monica Pita
